0001193125-26-134720 | 10-K | XBRL Viewer

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Stock Option Plan - Additional information (Detail) - USD ($) $ in Millions	12 Months Ended
	Dec. 31, 2025	Jun. 30, 2020
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Options available for future grant	953,496
Non-Vested Stock [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Unrecognized compensation costs related to unvested restricted stock outstanding	$ 0.4
Expected recognition period	1 year 9 months
the "2012 Plan" [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Options available for future grant	7,109
the "2020 Plan" [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Common stock reserved for future issuance	222,485
Share-based payment award, number of shares authorized	1,147,109	1,140,000
Options available for future grant	953,496

- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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+ Details

Insider Trading Arrangements	3 Months Ended
Insider Trading Arrangements	Dec. 31, 2025
Trading Arrangements, by Individual
Rule 10b5-1 Arrangement Adopted	false
Non-Rule 10b5-1 Arrangement Adopted	false
Rule 10b5-1 Arrangement Terminated	false
Non-Rule 10b5-1 Arrangement Terminated	false

Pay vs Performance Disclosure - USD ($) $ in Thousands	12 Months Ended
Pay vs Performance Disclosure - USD ($) $ in Thousands	Dec. 31, 2025	Dec. 31, 2024	Dec. 31, 2023
Pay vs Performance Disclosure
Net Income (Loss)	$ (4,176)	$ (4,679)	$ (4,679)

- Definition

The portion of profit or loss for the period, net of income taxes, which is attributable to the parent.

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-URI https://asc.fasb.org/1943274/2147482740/230-10-45-28

Reference 46: http://www.xbrl.org/2003/role/disclosureRef
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-SubTopic 10
-Name Accounting Standards Codification
-Section 45
-Paragraph 1A
-Subparagraph (a)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482790/220-10-45-1A

Reference 47: http://www.xbrl.org/2003/role/disclosureRef
-Topic 220
-SubTopic 10
-Name Accounting Standards Codification
-Section 45
-Paragraph 1B
-Subparagraph (a)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482790/220-10-45-1B

Reference 48: http://www.xbrl.org/2003/role/disclosureRef
-Topic 470
-SubTopic 20
-Name Accounting Standards Codification
-Section 65
-Paragraph 4
-Subparagraph (f)(4)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147481538/470-20-65-4

Reference 49: http://fasb.org/us-gaap/role/ref/legacyRef
-Topic 942
-SubTopic 220
-Name Accounting Standards Codification
-Section S99
-Paragraph 1
-Subparagraph (SX 210.9-04(22))
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147478524/942-220-S99-1

+ Details

Stock Option Plan - Share-Based Compensation Expense on All Employee and Non-Employee Awards (Detail) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2025	Dec. 31, 2024
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Stock based compensation expenses	$ 796	$ 435
Research and Development [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Stock based compensation expenses	210	17
General and Administrative [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Stock based compensation expenses	$ 586	$ 418

- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

+ References

+ Details

Accrued Expenses

12 Months Ended

Dec. 31, 2025

Payables and Accruals [Abstract]

Accrued Expenses

Accrued expenses consist of the following:


($ in thousands)	2025		2024
Preclinical services	$	123	$	97
Sales and use taxes		54		-
Professional services		23		79
	$	200	$	176

Property and Equipment, net (Tables)

12 Months Ended

Dec. 31, 2025

Property, Plant and Equipment [Abstract]

Component of Property and Equipment, Net

Property and equipment, net, consists of the following:


	December 31,			December 31,
($ in thousands)	2025			2024
Office and computer equipment	$	-		$	15
Laboratory equipment		98			-
		98			15
Less: accumulated depreciation		(7	)		(15	)
Property and equipment, net	$	91		$	-

Segment Information (Tables)

12 Months Ended

Dec. 31, 2025

Segment Reporting [Abstract]

Summary of Segment Reporting Information

The table below provides information about the Company’s revenue, significant segment expenses and other segment expenses.


	For the years ended December 31,
($ in thousands)	2025			2024
Revenues	$	5		$	10
Less segment expenses:
Research and development		1,363				362
General and administrative		2,867				4,460
Total operating and segment expense		4,230				4,822
Plus:
Change in fair value of warrant liability		(31	)			-
Other income, net		80				133
Segment Net loss	$	(4,176	)	$		(4,679	)

Income Taxes - Significant Component of Deferred Tax Assets (Detail) - USD ($) $ in Thousands	Dec. 31, 2025	Dec. 31, 2024
Net operating loss carryforwards	$ 163,254	$ 154,634
Deferred tax assets:
Start-up and pre-clinical studies	8,683	11,011
Research and development credit carryforwards	40,345	40,486
Stock-based compensation	766	699
Capitalized acquisition costs	556	1,050
Lease liability	0	0
Depreciation	0	1
Capitalized research expenses	0	5,400
Other	(20)	0
Deferred Tax Assets Gross	213,584	213,281
Less valuation allowance	(213,584)	(213,281)
Total deferred tax assets	0	0
Deferred tax liabilities:
Right-of-use asset	0	0
Total deferred tax liabilities	0	0
Net deferred taxes	$ 0	$ 0

Summary of Significant Accounting Policies - Schedule of Net loss Attributable to Common Shareholders (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2025	Dec. 31, 2024	Dec. 31, 2023
Accounting Policies [Abstract]
Net loss	$ (4,176)	$ (4,679)	$ (4,679)
Cumulative preferred dividends	(106)
Net loss attributable to common stockholders	$ (4,282)	$ (4,679)

- Definition

The portion of profit or loss for the period, net of income taxes, which is attributable to the parent.

+ References

+ Details

- Definition

Amount, after deduction of tax, noncontrolling interests, dividends on preferred stock and participating securities; of income (loss) available to common shareholders.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Topic 260
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Reference 14: http://www.xbrl.org/2003/role/disclosureRef
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-Section 45
-Paragraph 60B
-Subparagraph (c)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482689/260-10-45-60B

+ Details

Equity - Additional Information (Details) - USD ($)						1 Months Ended		12 Months Ended
Equity - Additional Information (Details) - USD ($)	Oct. 10, 2025	Aug. 18, 2025	Jul. 03, 2025	Jun. 01, 2025	Apr. 13, 2025	Jun. 30, 2025	Apr. 30, 2025	Dec. 31, 2025	Nov. 21, 2025	May 31, 2025	Dec. 31, 2024
Class of Stock [Line Items]
Common stock, shares authorized								50,000,000			50,000,000
Common stock, shares issued								2,349,480			1,601,252
Common stock aggregate fair value								$ 2,000			$ 2,000
Warrant exercise per share								$ 9.63		$ 4	$ 28.5
Grant date fair value								$ 195,000
Securities Purchase Agreement [Member]
Class of Stock [Line Items]
Common stock, shares issued				338,725				271,656
Shares price, per share				$ 3.36
Net proceeds				$ 1,910,000
Board of Directors [Member]
Class of Stock [Line Items]
Deferred board service fee			$ 37,000		$ 139,000
Common stock, shares issued			7,450		38,269				14,665
Common stock aggregate fair value					$ 112,000				$ 49,000
Number of stock options granted and fully vested		13,676			10,904
Fully vested stock options at exercise price		$ 2.32			$ 2.92
Fully vested stock options with aggregate fair value		$ 27,000			$ 27,000
Common Stock [Member]
Class of Stock [Line Items]
Shares issued as consideration for board service fees ( in shares)								60,384
Additional common stock issuance								338,725
Pre Funded Warrants [Member] \| Securities Purchase Agreement [Member]
Class of Stock [Line Items]
Shares price, per share				$ 3.359
Warrants to purchase common stock				271,674
Consulting Services [Member] \| Common Stock [Member]
Class of Stock [Line Items]
Shares issued as consideration for board service fees ( in shares)	53,832	10,775
Grant date fair value	$ 199,000	$ 25,000						$ 38,000
Additional common stock issuance								12,856
Consulting Services [Member] \| Stock Option [Member]
Class of Stock [Line Items]
Shares issued as consideration for board service fees ( in shares)		4,000
Grant date fair value		$ 8,000
Minimum
Class of Stock [Line Items]
Common stock, shares authorized			5,000,000
Minimum \| 2020 Equity Incentive Plan [Member]
Class of Stock [Line Items]
Common stock, shares authorized			130,745
Maximum
Class of Stock [Line Items]
Common stock, shares authorized			50,000,000
Maximum \| 2020 Equity Incentive Plan [Member]
Class of Stock [Line Items]
Common stock, shares authorized			1,130,745
Series A-1 Preferred Stock [Member] \| Subscription Arrangement [Member]
Class of Stock [Line Items]
Shares sold							500
Preferred stock par value or stated value							$ 0.001
Preferred stock price per share							$ 1,000
Convertible preferred stock aggregate purchase price							$ 500,000
Series A One Preferred Stock [Member]
Class of Stock [Line Items]
Shares sold								500			0
Preferred stock par value or stated value								$ 0.001			$ 0.001
Convertible preferred stock designated shares							1,000
Preferred stock conversion price							$ 2.76
Percentage of preferred stock dividends payablein shares							10.00%
Undeclared cumulative dividends								$ 60,000
Series A Two Preferred Stock [Member]
Class of Stock [Line Items]
Shares sold								850			0
Preferred stock par value or stated value								$ 0.001			$ 0.001
Convertible preferred stock designated shares						1,000
Preferred stock conversion price						$ 4.49
Percentage of preferred stock dividends payablein shares						10.00%
Undeclared cumulative dividends								$ 45,000
Series A Two Preferred Stock [Member] \| Subscription Arrangement [Member]
Class of Stock [Line Items]
Shares sold						850
Preferred stock par value or stated value						$ 0.001
Preferred stock price per share						$ 1,000
Convertible preferred stock aggregate purchase price						$ 850
Series A One and Series A Two Convertible Preferred Stock [Member]
Class of Stock [Line Items]
Percentage of preferred stock dividends payablein shares								10.00%

Property and Equipment, net - Additional Information (Detail) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2025	Dec. 31, 2024
Depreciation	$ 7	$ 2

Property and Equipment, net - Component of Property and Equipment, Net (Detail) - USD ($) $ in Thousands	Dec. 31, 2025	Dec. 31, 2024
Property, Plant and Equipment [Line Items]
Property and equipment, Gross	$ 98	$ 15
Less: accumulated depreciation	(7)	(15)
Property and equipment, net	91	0
Office and computer equipment [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, Gross	0	15
Laboratory equipment [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, Gross	$ 98	$ 0

Insider Trading Policies and Procedures	12 Months Ended
Insider Trading Policies and Procedures	Dec. 31, 2025
Insider Trading Policies and Procedures [Line Items]
Insider Trading Policies and Procedures Adopted	true

Summary of Significant Accounting Policies - Additional Information (Detail) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2025	Dec. 31, 2024
Summary Of Significant Accounting Policies [Line Items]
Stock based compensation expenses	$ 796	$ 435
Collaboration revenue	$ 5	10
Office and computer equipment [Member]
Summary Of Significant Accounting Policies [Line Items]
Property and equipment useful life	3 years
Software [Member]
Summary Of Significant Accounting Policies [Line Items]
Property and equipment useful life	3 years
Laboratory equipment [Member]
Summary Of Significant Accounting Policies [Line Items]
Property and equipment useful life	5 years
Employee Stock Option
Summary Of Significant Accounting Policies [Line Items]
Stock based compensation expenses	$ 400	400
Stock Options and Restricted Stock [Member]
Summary Of Significant Accounting Policies [Line Items]
Stock based compensation expenses	$ 800	$ 400

- Definition

Amount, excluding tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value added and excise.

+ References

Reference 1: http://www.xbrl.org/2003/role/exampleRef
-Topic 220
-SubTopic 40
-Name Accounting Standards Codification
-Section 55
-Paragraph 4
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Reference 3: http://www.xbrl.org/2003/role/disclosureRef
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Reference 4: http://www.xbrl.org/2003/role/disclosureRef
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Reference 5: http://www.xbrl.org/2003/role/disclosureRef
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Reference 6: http://www.xbrl.org/2003/role/disclosureRef
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-URI https://asc.fasb.org/1943274/2147479806/606-10-50-4

+ Details

Warrants - Summary of Warrant Activity (Details) - $ / shares	12 Months Ended
	Dec. 31, 2025	Dec. 31, 2024
Warrants Disclosure [Abstract]
Number of Shares, Beginning Balance	26,552
Weighted- Average Exercise Price Outstanding	$ 28.5
Weighted- Average Contractual Term (Years)	3 years 8 months 23 days	2 years 9 months
Number of Share Granted	351,574
Number Of share Exercised	(271,674)
Weighted- Average Exercise Price, Granted	$ 0.76
Weighted- Average Exercise Price, Exercised	0.001
Weighted- Average Exercise Price Outstanding	$ 9.63
Number of Shares, Ending Balance	106,452

Preferred Stock and Stockholders' Equity (Deficit) - Additional Information (Detail) - USD ($) $ / shares in Units, $ in Thousands	12 Months Ended
	Dec. 31, 2025	Jul. 03, 2025	May 31, 2025	Dec. 31, 2024
Equity [Line Items]
Common stock, shares authorized	50,000,000			50,000,000
Initial Public Offering of Common Stock	$ 0.001			$ 0.001
Aggregate offering price	$ 998
Warrant exercise per share	$ 9.63		$ 4	$ 28.5
Common stock, shares outstanding	2,349,480			1,601,252
Common Stock
Equity [Line Items]
Shares issued as consideration for board service fees ( in shares)	60,384
Shares issued as consideration for services (in shares)	77,463
Common stock, shares outstanding	2,349,480
Common Stock, shares reserved for future issuance	328,937
Maximum [Member]
Equity [Line Items]
Common stock, shares authorized		50,000,000

Stock Option Plan (Tables)

12 Months Ended

Dec. 31, 2025

Share-Based Payment Arrangement [Abstract]

Share-Based Compensation Expense on All Employee and Non-Employee Awards

The following table presents share-based compensation expense on all employee and non-employee awards included in the accompanying statements of operations as follows:


	For the years ended December 31,
(in thousands)	2025		2024
Research and development	$	210	$	17
General and administrative		586		418
Stock-based compensation expense	$	796	$	435

Stock Option Activity Under Stock Option Plan

Stock option activity under the Company's stock options plans for the years ending December 31, 2025 and 2024 were as follows:


(in thousands, except share and per share data)	Number of Shares			Weighted- Average Exercise Price		Weighted- Average Contractual Term (Years)		Aggregate Intrinsic Value
Outstanding, December 31, 2024		33,237		$	153.79		7.15	$	—
Granted		196,580			4.33
Exercised		-			-
Cancelled		(7,332	)		176.07
Outstanding, December 31, 2025		222,485		$	23.98		9.04	$	31
Options exercisable, December 31, 2025		96,435		$	49.11		8.54	$	31
Options available for future grant, December 31, 2025		953,496

Assumptions for Volatility, Expected Life, Dividend Yield and Risk-Free Interest Rate

The assumptions for volatility, expected life, dividend yield and risk-free interest rate are presented in the table below:


	For the years ended December 31,
	2025	2024
Risk-free interest rate	4.05-4.15%	3.70 - 4.09%
Expected life in years	5.04-6.06	5.04-6.06
Expected volatility	113.26-127.03%	112.17 -170.50%
Expected dividend yield	—%	—%

Summary of Significant Accounting Policies (Tables)

12 Months Ended

Dec. 31, 2025

Accounting Policies [Abstract]

Assets and Liabilities Measured at Fair Value on Recurring Basis

Assets and liabilities measured at fair value on a recurring and nonrecurring basis as of December 31, 2025 and 2024 are as follows:


($ in thousands)			Fair Value Measurements at Reporting Date Using
Description	Balance as of December 31, 2025		Quoted Prices in Active Markets for Identical Assets/Liabilities (Level 1)		Significant Other Observable Inputs (Level 2)		Significant Unobservable Inputs (Level 3)
Cash equivalents	$	1,135	$	1,135	$	—	$	—


($ in thousands)			Fair Value Measurements at Reporting Date Using
Description	Balance as of December 31, 2024		Quoted Prices in Active Markets for Identical Assets/Liabilities (Level 1)		Significant Other Observable Inputs (Level 2)		Significant Unobservable Inputs (Level 3)
Cash equivalents	$	779	$	779	$	—	$	—

Potentially Dilutive Shares Excluded from Computation of Diluted Net Loss Per Share

Such potential common shares on December 31, 2025 and 2024 consist of the following:


	December 31,
	2025		2024
Common stock options		222,485		33,237
Warrants		106,452		26,552
Series A-1 Preferred Stock		181,159		-
Series A-2 Preferred Stock		189,309		-
		699,405		59,789

Schedule of Net Loss Attributable to Common Shareholders

The following table show the net loss attributable to common shareholders after including undeclared cumulative preferred dividend used to calculate the basic and diluted earnings per share, as shown on the statement of operations (See Note 6. Equity - Series A-1 and A-2 Preferred Stock Cumulative Dividends):


	For the years ended December 31,
	2025			2024
Net loss	$	(4,176	)	$	(4,679	)
Cumulative preferred dividends		(106	)		-
Net loss attributable to common stockholders	$	(4,282	)	$	(4,679	)

Commitments and Contingencies - Additional Information (Details) - USD ($)		12 Months Ended
	Jul. 01, 2025	Dec. 31, 2025	Dec. 31, 2024	Jul. 02, 2025	May 31, 2025	Aug. 31, 2004
Accrued Payments
Collaboration revenue		$ 5,000	$ 10,000
Prepaid expenses and other current assets		600,000	1,659,000
Other long-term assets		887,000	0
Accounts payable		613,000	516,000
Periodic payment for agreement settlement		285,000
Strategic and advisory services fee	$ 250,000
Tax liability		54,000
Research and development expense		1,363,000	362,000
Revenue		$ 5,000	$ 10,000
Warrant exercise per share		$ 9.63	$ 28.5		$ 4
Chief Executive Officer [Member]
Accrued Payments
Annual base salary	$ 275,000
Chief Executive Officer [Member] \| Stock Option [Member] \| Common Stock [Member]
Accrued Payments
Stock option purchase of common stock exercise price				$ 5.06
Stock option to purchase shares				130,000
The University of Texas MD Anderson Cancer Center and The Texas A & M University System [Member]
Accrued Payments
Milestone maximum payment						$ 4,500,000
Prepaid expenses and other current assets		$ 222,000
The University of Texas MD Anderson Cancer Center and The Texas A & M University System [Member] \| Royalty [Member]
Accrued Payments
Payment under license agreement		0	$ 0
he University of Texas MD Anderson Cancer Center [Member]
Accrued Payments
Accounts payable		143,000	257,000
Collaboration Agreement with Solasia Pharma KK [Member] \| Royalty [Member]
Accrued Payments
Collaboration revenue		5,000	10,000
Revenue		$ 5,000	$ 10,000

Stock Option Plan - Assumptions for Volatility, Expected Life, Dividend Yield and Risk-Free Interest Rate (Detail)	12 Months Ended
	Dec. 31, 2025	Dec. 31, 2024
Risk-free interest rate, Minimum	4.05%	3.70%
Risk-free interest rate, Maximum	4.15%	4.09%
Expected volatility, Minimum	113.26%	112.17%
Expected volatility, Maximum	127.03%	170.50%
Expected dividend yield	0.00%	0.00%
Maximum [Member]
Expected life in years	6 years 21 days	6 years 21 days
Minimum [Member]
Expected life in years	5 years 14 days	5 years 14 days

Warrants

12 Months Ended

Dec. 31, 2025

Warrants Disclosure [Abstract]

Warrants

The following is a summary of the Company's warrant activity for the years ended December 31, 2025:


(in thousands, except share and per share data)	Number of Shares			Weighted- Average Exercise Price		Weighted- Average Contractual Term (Years)
Outstanding, December 31, 2024		26,552		$	28.50	2.75
Granted		351,574			0.76
Exercised		(271,674	)		0.001
Outstanding, December 31, 2025		106,452		$	9.63		3.73

In May 2025, the Company entered into an equity purchase agreement with an investor under which the Company has the option to sell up to $25.0 million of common stock over a period of 24 months at 97% of the prior trading day’s volume-weighted average price, subject to volume and ownership limitations. In connection with the agreement, the Company issued a warrant to purchase 79,900 shares of common stock at $4.00 per share, with a five-year term.

Due to anti-dilution and variable pricing features, the warrant was initially classified as a derivative liability measured at fair value using the Black-Scholes model, which was determined to be approximately equivalent to a lattice or monte carlo model. On the issuance date, the fair value of the derivative liability totaled $177, with a corresponding increase in deferred issuance costs for the same amount, which is included in other assets in the balance sheet and will be amortized as a reduction to the proceeds received equity instruments sold pursuant to the agreement or upon its termination in the event the entirety of the shares are not sold. On June 9, 2025, the Company and the investor agreed to amend the warrant to introduce a $0.57 floor price, eliminate certain share-count adjustments, and remove certain fundamental transaction rights. As a result, the warrant, as amended, qualified for equity classification, was remeasured at fair value, and was reclassified from liabilities to equity, which resulted in a charge of $31 recognized as a change in fair value of derivative liability and is included in other expense in the statement of operations.

The fair value of the warrant issued to the investor was initially measured using the Black-Scholes option pricing model as of May 19, 2025, based on the following assumptions: expected volatility of 118.36%, risk-free interest rate of 4.19%, dividend yield of 0%, expected term of 5.0 years, stock price of $3.12, and exercise price of $3.48. On June 9, 2025, in connection with the amendment of the warrant terms, the fair value was remeasured using updated inputs, which included an expected volatility of 125.81%, risk-free interest rate of 4.09%, dividend yield of 0%, expected term of 5.0 years, stock price of $3.12, and a revised exercise price of $3.36. Both valuations reflect management’s best estimates at the respective measurement dates. Assumptions regarding volatility, expected term, dividend yield and risk-free interest rate are required for the Black-Scholes model. The volatility assumption is based on the historical experience

Income Taxes - Additional Information (Detail) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2025	Dec. 31, 2024
Income Taxes [Line Items]
Net operating loss carryforwards	$ 163,254	$ 154,634
Deferred tax assets operating loss carryforwards without expire date	436,000
Research and development credit carryforwards	40,345	40,486
Reduced credits carryforward		0
Uncertain tax positions adjustment	0	$ 0
Increase (decrease) in deferred tax assets	303
Interest and penalties	0
Domestic Tax Authority [Member]
Income Taxes [Line Items]
Net operating loss carryforwards	$ 775,000
Net operating loss carryforwards, expiration date	2037
Federal and State [Member]
Income Taxes [Line Items]
Deferred tax assets operating loss carryforwards with expire date	$ 339,000
Net operating loss carryforwards, expiration date	2045
Federal and State [Member] \| Research Tax Credit Carryforward
Income Taxes [Line Items]
Research and development credit carryforwards	$ 40,300
State and Local Jurisdiction [Member]
Income Taxes [Line Items]
Net operating loss carryforwards	498,000
Increase (decrease) in deferred tax assets	0
Florida [Member]
Income Taxes [Line Items]
Gross net operating loss	$ 10,900

Subsequent Events - Additional Information (Details) - USD ($) $ in Thousands		12 Months Ended
	Jan. 12, 2026	Dec. 31, 2025
Subsequent Event [Line Items]
Grant date fair value		$ 195
Common Stock [Member]
Subsequent Event [Line Items]
Shares issued as consideration for board service fees ( in shares)		60,384
Subsequent Event [Member] \| Common Stock [Member]
Subsequent Event [Line Items]
Shares issued as consideration for board service fees ( in shares)	16,867
Grant date fair value	$ 49

Segment Information - Additional Information (Details)	12 Months Ended
Segment Information - Additional Information (Details)	Dec. 31, 2025
Segment Reporting [Abstract]
Segment Reporting, CODM, Individual Title and Position or Group Name [Extensible Enumeration]	Chief Executive Officer [Member]
Segment Reporting, CODM, Profit (Loss) Measure, How Used, Description	The Company’s CODM assesses financial performance and allocates resources based on operating results which are also reported on the statements of operations.

Equity

12 Months Ended

Dec. 31, 2025

Equity [Abstract]

Equity

Increase in Authorized Shares

On July 3, 2025, the Company stockholders approved an amendment to the Company’s Certificate of Incorporation to increase the number of authorized shares of common stock from 5,000,000 to 50,000,000. The amendment was filed with the Secretary of State of the State of Delaware and became effective upon filing.

Equity Incentive Plan Amendment

On July 3, 2025, the Company's stockholders approved an amendment to the Company’s 2020 Equity Incentive Plan to increase the number of shares of common stock authorized for issuance under the plan from 130,745 to 1,130,745 shares.

Series A-1 Preferred Stock

In April 2025, the Company entered into a Subscription Agreement (the “A-1 Agreement”), with an accredited investor, pursuant to which the Company sold 500 shares of Series A-1 Convertible Preferred Stock, par value of $0.001 per share (the “Series A-1 Preferred Stock”), at a price per share of $1,000 (the “Preferred Offering”) for an aggregate purchase price of $0.5 million. The Preferred Offering also relates to the offering of the shares of the Company's common stock (the "Common Stock") issuable upon the conversion of or otherwise pursuant to the terms of the Series A-1 Preferred Stock.

In connection therewith, the Company filed with the Secretary of State of the State of Delaware the Certificate of Designation of Series A-1 Convertible Preferred Stock of the Company, designating 1,000 shares of preferred stock as Series A-1 Preferred Stock.

Series A-1 Preferred Stock together with the aggregate accrued or accumulated and unpaid dividends thereon, is convertible, at any time at option of the holder, into shares of Common Stock at initial fixed “Conversion Price” of $2.76 per share, subject to customary anti-dilution provisions. Prior thereto, the holders of Series A-1 Preferred Stock are entitled to receive dividends at a rate of 10% per annum, payable in shares of Series A-1 Preferred Stock, if and when declared by the Board of Directors. In addition, to the extent any other dividends or distributions are declared for holders of the common stock, the holders of Series A-1 Preferred Stock have participation rights on an as-converted basis. The holders of Series A-1 Preferred Stock are entitled to vote, together as a single class, on any and all matters presented to the stockholders of the Company for their action on an as-converted basis, a number of votes equal to the number of shares of common stock into which the shares of Series A-1 Preferred Stock are convertible under the terms of the Certificate of Designation.

Director Compensation

On April 13, 2025, the Board of Directors of the Company elected to receive compensation in the form of shares of common stock and stock

options in lieu of cash for the then outstanding cumulative deferred board service fees for the first quarter of 2025, totaling $139. Accordingly, the Company issued 38,269 shares of common stock with an aggregate fair value of $112 and granted 10,904 fully vested stock options, with an exercise price of $2.92 per share and an aggregate grant date fair value of $27.

On July 3, 2025, the Board of Directors of the Company elected to receive compensation in the form of shares of common stock and stock options in lieu of cash for the second quarter board service fees. The total deferred board service fees amounted to $37. In exchange for these deferred fees, the Company issued 7,450 shares of common stock and on August 18, 2025 granted 13,676 fully vested stock options, with an exercise price of $2.32 per share and an aggregate grant date fair value of $27.

On November 21, 2025, members of the Board of Directors of the Company elected to receive compensation in equity rather than in cash for their third quarter board service fees. Accordingly, the Company issued 14,665 shares of common stock with an aggregate fair value of $49.

Securities Purchase Agreement for Registered Direct Offering

In June 2025, the Company entered into a Securities Purchase Agreement with certain institutional investors, pursuant to which the Company agreed to sell (i) 338,725 shares of common stock at a purchase price of $3.36 per share and (ii) 271,674 pre-funded warrants to purchase common stock at a purchase price of $3.359 per warrant share, in a registered direct offering. In connection therewith, Company received net proceeds totaling $1.91 million after deduction of transaction related expenses. As of December 31, 2025, all pre-funded warrants had been exercised, including certain warrants exercised on a cashless basis, resulting in the issuance of an aggregate of 271,656 shares of common stock.

Series A-2 Preferred Stock

In June 2025, the Company entered into a subscription agreement with certain accredited investors, pursuant to which the Company sold, in a private placement, 850 shares of Series A-2 Convertible Preferred Stock, par value $0.001 per share, at a price of $1,000 per share, for aggregate gross proceeds of $0.85 million.

In connection therewith, the Company filed with the Secretary of State of the State of Delaware the Certificate of Designation of Series A-2 Convertible Preferred Stock of the Company, designating 1,000 shares of preferred stock as Series A-2 Preferred Stock.

Series A-2 Preferred Stock, together with the aggregate accrued or accumulated and unpaid dividends thereon, is convertible, at any time at the option of the holder, into shares of Common Stock at an initial fixed “Conversion Price” of $4.49 per share, subject to customary anti-dilution provisions. Prior thereto, the holders of Series A-2 Preferred Stock are entitled to receive dividends at a rate of 10% per annum, payable in shares of Series A-2 Preferred Stock, if and when declared by the Board of Directors. In addition, to the extent any other dividends or distributions are declared for holders of the Common Stock, the holders of Series A-2 Preferred Stock have participation rights on an as-converted basis. The holders of Series A-2 Preferred Stock are entitled to vote, together as a single class, on any and all matters presented to the stockholders of the Company for their action on an as-converted basis, a number of votes equal to the number of shares of Common Stock into which the shares of Series A-2 Preferred Stock are convertible under the terms of the Certificate of Designation.

Series A-1 and A-2 Preferred Stock Cumulative Dividends

Cumulative dividends on the Company’s Series A-1 and Series A-2 Convertible Preferred Stock accrue at 10% per annum and compound quarterly by increasing the liquidation preference. Undeclared cumulative dividends are not recorded as a liability. Because the Company reported a net loss for the periods presented, cumulative preferred dividends increased the net loss attributable to common stockholders in the earnings-per-share calculation. As of December 31, 2025, undeclared cumulative dividends totaled $60 for Series A-1 and $45 for Series A-2.

Consulting Services

On August 18, 2025, the Company issued 10,775 shares of common stock for services, with an aggregate grant-date fair value of $25 to the Company's Vice President of Finance. In addition, the Company issued 4,000 stock options to the consultant with a grant date fair value of $8. One-sixteenth of the shares underlying the option vest in equal quarterly installments measured from August 18, 2025, with the first vesting occurring on November 18, 2025.

On October 10, 2025, the Company issued 53,832 shares of common stock for services, with an aggregate grant-date fair value of $199. The issuance partially settled accounts payable outstanding at September 30, 2025 pursuant to a revised consulting agreement. For services render through out the remainder of the year ended December 31, 2025 the Company issued an aggregate of 12,856 shares of common stock for services, with an aggregate grant-date fair value of $38 pursuant to the consulting agreement.

- Definition

The entire disclosure for equity.

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+ Details

Cover Page - USD ($)	12 Months Ended
Cover Page - USD ($)	Dec. 31, 2025	Mar. 31, 2026	Jun. 30, 2025
Cover [Abstract]
Document Type	10-K
Amendment Flag	false
Document Period End Date	Dec. 31, 2025
Document Fiscal Year Focus	2025
Document Fiscal Period Focus	FY
Entity Registrant Name	Alaunos Therapeutics, Inc.
Entity Central Index Key	0001107421
Current Fiscal Year End Date	--12-31
Entity Filer Category	Non-accelerated Filer
Trading Symbol	TCRT
Document Transition Report	false
Document Annual Report	true
Security Exchange Name	NASDAQ
Title of 12(b) Security	Common Stock
Entity File Number	001-33038
Entity Incorporation, State or Country Code	DE
Entity Address, Address Line One	501 E. Las Olas Blvd.,
Entity Address, Address Line Two	Suite 300
Entity Address, City or Town	Fort Lauderdale,
Entity Address, State or Province	FL
Entity Address, Postal Zip Code	33301
Entity Tax Identification Number	84-1475642
City Area Code	346
Local Phone Number	355-4099
Entity Well-known Seasoned Issuer	No
Entity Current Reporting Status	Yes
Entity Voluntary Filers	No
Entity Interactive Data Current	Yes
Entity Shell Company	false
Entity Small Business	true
Entity Emerging Growth Company	false
Document Financial Statement Error Correction [Flag]	false
ICFR Auditor Attestation Flag	false
Entity Common Stock, Shares Outstanding		2,378,253
Entity Public Float			$ 9,608,631
Auditor Name	Cherry Bekaert LLP
Auditor Location	Tampa, Florida
Auditor Firm ID	677
Auditor Opinion [Text Block]	Opinion on the Financial Statements We have audited the accompanying balance sheet of Alaunos Therapeutics, Inc. (the “Company”) as of December 31, 2025, and the related statements of operations, stockholders’ equity, and cash flows the year ended December 31, 2025, and the related notes (collectively referred to as the “financial statements”). In our opinion, the financial statements present fairly, in all material respects, the financial position of the Company as of December 31, 2024, and the results of its operations and its cash flows for the year ended December 31, 2025, in conformity with accounting principles generally accepted in the United States of America. The financial statements of the Company as of and for the year ended December 31, 2023, before the retroactive adjustments described in Note 3 with respect to the July 2024 one-for-ten reverse stock split were audited by other auditors whose report, dated April 1, 2024, expressed an unqualified opinion, with an explanatory paragraph expressing substantial doubt regarding the Company’s ability to continue as a going concern, on those statements. We also audited the adjustments described in Note 3 that were applied retroactively to the 2023 financial statements to reflect the July 2024 one-for-ten reverse stock split and the related disclosures included therein. In our opinion, such adjustments and related disclosures are appropriate and have been properly applied. We were not engaged to audit, review, or apply any procedures to the 2023 financial statements of the Company other than with respect to the adjustments and disclosures referred to herein and, accordingly, we do not express an opinion or any other form of assurance on the 2023 financial statements taken as a whole.
Documents Incorporated by Reference	DOCUMENTS INCORPORATED BY REFERENCE Portions of the Proxy Statement for the Registrant's 2026 Annual Meeting of Stockholders are incorporated by reference into Part III of this Annual Report on Form 10-K.

Stock Option Plan - Stock Option Activity Under Stock Option Plan (Detail) - USD ($) $ / shares in Units, $ in Thousands	12 Months Ended
	Dec. 31, 2025	Dec. 31, 2024
Number of Shares
Beginning Balance	33,237
Granted	196,580
Exercised	0
Cancelled	(7,332)
Ending Balance	222,485	33,237
Options exercisable, at end of period	96,435
Options available for future grant	953,496
Weighted Average Exercise Price
Beginning Balance	$ 153.79
Granted	4.33
Exercised	0
Cancelled	176.07
Ending Balance	23.98	$ 153.79
Options exercisable, at end of period	$ 49.11
Weighted Average Contractual Term (Years)
Outstanding, period	9 years 14 days	7 years 1 month 24 days
Options exercisable, at end of period	8 years 6 months 14 days
Aggregate Intrinsic Value
Outstanding, at beginning of period	$ 0
Outstanding, at end of period	31	$ 0
Options exercisable, at end of period	$ 31

Stock Option Plan

12 Months Ended

Dec. 31, 2025

Share-Based Payment Arrangement [Abstract]

Stock Option Plan

The Company adopted the 2020 Equity Incentive Plan, or the 2020 Plan, in June 2020. As of December 31, 2025, there were 222,485 shares reserved for issuance and 953,496 shares available for future grant. The Company reserved 1,140,000 shares for issuance plus a carryover of 7,109 shares from the 2012 Plan for a total of 1,147,109 shares. In addition, returning shares from the 2012 Plan are available for issuance under the 2020 Plan.

Stock options generally vest ratably in either quarterly or annual installments over three or four years, commencing on the first anniversary of the grant date and have contractual terms of ten years. Stock options to directors generally vest ratably over one or two years and have contractual terms of ten years. Stock options are valued using the Black-Scholes option pricing model and compensation is recognized based on such fair value over the period of vesting on a straight-line basis.

The following table presents share-based compensation expense on all employee and non-employee awards included in the accompanying statements of operations as follows:


	For the years ended December 31,
(in thousands)	2025		2024
Research and development	$	210	$	17
General and administrative		586		418
Stock-based compensation expense	$	796	$	435

Stock option activity under the Company's stock options plans for the years ending December 31, 2025 and 2024 were as follows:


(in thousands, except share and per share data)	Number of Shares			Weighted- Average Exercise Price		Weighted- Average Contractual Term (Years)		Aggregate Intrinsic Value
Outstanding, December 31, 2024		33,237		$	153.79		7.15	$	—
Granted		196,580			4.33
Exercised		-			-
Cancelled		(7,332	)		176.07
Outstanding, December 31, 2025		222,485		$	23.98		9.04	$	31
Options exercisable, December 31, 2025		96,435		$	49.11		8.54	$	31
Options available for future grant, December 31, 2025		953,496

On December 31, 2025, total unrecognized compensation costs related to non-vested stock options outstanding amounted to $0.4 million, which is expected to be recognized over a weighted-average period of 1.75 years.

The assumptions for volatility, expected life, dividend yield and risk-free interest rate are presented in the table below:


	For the years ended December 31,
	2025	2024
Risk-free interest rate	4.05-4.15%	3.70 - 4.09%
Expected life in years	5.04-6.06	5.04-6.06
Expected volatility	113.26-127.03%	112.17 -170.50%
Expected dividend yield	—%	—%

Employee Benefit Plan - Additional Information (Detail) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2025	Dec. 31, 2024
Retirement Benefits [Abstract]
Defined benefit plan contributions by employer	$ 13	$ 0

- Definition

Amount of contribution received by defined benefit plan from employer which increases plan assets.

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Reference 9: http://www.xbrl.org/2003/role/disclosureRef
-Topic 715
-SubTopic 20
-Name Accounting Standards Codification
-Section 50
-Paragraph 1
-Subparagraph (b)(3)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147480506/715-20-50-1

Reference 10: http://www.xbrl.org/2003/role/exampleRef
-Topic 715
-SubTopic 20
-Name Accounting Standards Codification
-Section 50
-Paragraph 1
-Subparagraph (d)(ii)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147480506/715-20-50-1

Reference 11: http://www.xbrl.org/2003/role/exampleRef
-Topic 715
-SubTopic 20
-Name Accounting Standards Codification
-Section 50
-Paragraph 1
-Subparagraph (d)(iv)(01)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147480506/715-20-50-1

+ Details

Summary of Significant Accounting Policies (Policies)

12 Months Ended

Dec. 31, 2025

Accounting Policies [Abstract]

Basis of Presentation

The accompanying financial statements have been prepared in accordance with accounting principles generally accepted in the United States of America (“U.S. GAAP”).

Use of Estimates

The preparation of financial statements in conformity with U.S. GAAP requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities and the disclosure of contingent assets and liabilities at the date of the financial statements and the reported amounts of revenue and expenses during the reporting period. Although the Company regularly assesses these estimates, actual results could differ from those estimates. Changes in estimates are recorded in the period in which they become known.

The Company’s most significant estimates and judgments used in the preparation of the financial statements are:

•

Clinical trial expenses and other research and development expenses;

•

Collaboration agreements;

•

Fair value measurements of stock-based compensation; and

•

Income taxes.

Cash and Cash Equivalents

Cash equivalents consist primarily of demand deposit accounts, certificates of deposit and deposits in short-term U.S. treasury money market mutual funds. Cash equivalents are stated at cost, which approximates fair market value.

Concentrations of Credit Risk

Financial instruments which potentially subject the Company to concentrations of credit risk consist principally of cash and cash equivalents. The Company maintains cash accounts in commercial banks, which may, at times, exceed federally insured limits. The Company has not experienced any losses in such accounts. The Company believes it is not exposed to any significant credit risk on cash and cash equivalents.

Property and Equipment

Property and equipment are stated at cost, less accumulated depreciation and amortization. Depreciation and amortization is calculated on a straight-line basis using the following periods, which represent the estimated useful lives of the assets:


Office and computer equipment		3 years
Software		3 years
Laboratory equipment		5 years

Operating Segments

Operating segments are identified as components of an enterprise for which separate discrete financial information is available for evaluation by the Company’s chief operating decision maker (“CODM”) and relied upon when making decisions regarding resource allocation and assessing performance. When evaluating the Company’s financial performance, the CODM reviews total revenues, total expenses, and expenses by functional classification; using this information to make decisions on a company-wide basis. The Company views its operations and manages its business in one operating segment.

Warrants

The Company assesses whether warrants issued require accounting as derivatives. The Company determined that the warrants were (1) indexed to the Company’s own stock and (2) classified in stockholders’ equity in accordance with Financial Accounting Standards Board, or FASB, ASC Topic 815, Derivatives and Hedging. As such, the Company has concluded the warrants meet the scope exception for determining whether the instruments require accounting as derivatives and should be classified in stockholders’ equity.

Derivative Liabilities

In accordance with applicable accounting standards, upon issuance of financial instruments, whether stand alone or embedded, the Company performs an analysis to determine the appropriate classification of the financial instrument as either a derivative liability, or if certain conditions are met, as equity. Derivative liabilities are initially recorded at fair value and subsequently remeasures the derivative liability at each reporting period with changes in fair value recognized in earnings. The Company continually evaluates the classification and if the terms of the agreement are modified, the Company performs an assessment of the impact. Upon modification, if the instrument qualifies for equity classification, at that time it is remeasured at fair value, with changes in fair value since last measurement recognized in earnings and thereafter the balance is reclassified at its then fair value to equity. During the year ended December 31, 2025, the Company determined that certain warrants initially qualified as derivative liabilities. Such warrants were subsequently modified at which point the warrants qualified for equity classification. See further discussion in Note 9 - Warrants.

Fair Value Measurements

The Company has certain financial assets and liabilities recorded at fair value which have been classified as Level 1, 2 or 3 within the fair value hierarchy as described in the accounting standards for fair value measurements.

•

Level 1—Quoted prices in active markets for identical assets or liabilities.

•

Level 2—Inputs other than Level 1 that are observable, either directly or indirectly, such as quoted prices for similar assets or liabilities; quoted prices in markets that are not active; or other inputs that are observable or can be corroborated by observable market data for substantially the full term of the assets or liabilities.

•

Level 3—Unobservable inputs that are supported by little or no market activity and that are significant to the fair value of the assets or liabilities.

Assets and liabilities measured at fair value on a recurring and nonrecurring basis as of December 31, 2025 and 2024 are as follows:


($ in thousands)			Fair Value Measurements at Reporting Date Using
Description	Balance as of December 31, 2025		Quoted Prices in Active Markets for Identical Assets/Liabilities (Level 1)		Significant Other Observable Inputs (Level 2)		Significant Unobservable Inputs (Level 3)
Cash equivalents	$	1,135	$	1,135	$	—	$	—


($ in thousands)			Fair Value Measurements at Reporting Date Using
Description	Balance as of December 31, 2024		Quoted Prices in Active Markets for Identical Assets/Liabilities (Level 1)		Significant Other Observable Inputs (Level 2)		Significant Unobservable Inputs (Level 3)
Cash equivalents	$	779	$	779	$	—	$	—

The cash equivalents represent demand deposit accounts and deposits in a short-term United States treasury money market mutual fund quoted in an active market and classified as a Level 1 asset. There have been no changes to the valuation methods during the years ended December 31, 2025 and 2024.

Revenue Recognition from Collaboration Agreements

Revenue for the year ended December 31, 2025 consisted of $5 and for the year ended December 31, 2024 consisted of $10. For the years ended December 31, 2025 and 2024, the Company recognized revenue through its Collaboration Agreement with Solasia Pharma K.K. primarily due to the achievement of milestones, as further described in Note 5, Commitments and Contingencies.

Research and Development Costs

Research and development expenses are recognized as incurred. The Company is required to estimate accrued research and development expenses as of each balance sheet date based on the facts and circumstances known at that time. This process includes reviewing open contracts and purchase orders, communicating with internal personnel and third-party service providers, and estimating the amount of services performed and the related costs incurred for which invoices have not yet been received.

The Company’s research and development activities are primarily related to its preclinical obesity and metabolic disorders program, including the development of oral small molecules for obesity and other metabolic disorders. The Company also incurs limited costs related to its historical oncology focused cell therapy programs.

Estimated accrued research and development expenses primarily include amounts due to third-party vendors supporting preclinical development, manufacturing, regulatory, and other research and development activities. The Company records accruals based on its estimates of the services received and efforts expended under contractual arrangements. Certain agreements may involve milestone-based or uneven payment terms, and payments to vendors may, at times, exceed the level of services provided as of the reporting date, resulting in prepaid research and development assets.

Significant judgment is required in estimating accrued research and development expenses. Differences between the Company’s estimates and actual amounts incurred are recorded in the period in which such differences become known. Although the Company does not expect these estimates to be materially different from actual results, changes in the status or timing of services performed may result in reported amounts being higher or lower in any particular period.

Income Taxes

Income taxes are accounted for under the liability method. Deferred tax assets and liabilities are recognized for the estimated future tax consequences of temporary differences between the financial statement carrying amounts and their respective tax bases. Deferred tax assets and liabilities are measured using enacted tax rates expected to apply to taxable income in the year in which the temporary differences are expected to be recovered or settled. The Company evaluates the realizability of its deferred tax assets and establishes a valuation allowance when it is more likely than not that all or a portion of deferred tax assets will not be realized.

The Company accounts for uncertain tax positions using a “more-likely-than-not” threshold for recognizing and resolving uncertain tax positions. The evaluation of uncertain tax positions is based on factors including, but not limited to, changes in tax law, the measurement of tax positions taken or expected to be taken in tax returns, the effective settlement of matters subject to audit, new audit activity and changes in facts or circumstances related to a tax position. The Company evaluates this tax position on an annual basis. The Company also accrues for potential interest and penalties related to unrecognized tax benefits in income tax expense (Refer to Note 11, Income Taxes).

Accounting for Stock-Based Compensation

Stock-based compensation cost is measured at the grant date based on the estimated fair value of the award and is recognized as expense over the employee’s requisite service period. Stock-based compensation expense is based on the number of awards ultimately expected to vest and is reduced for forfeitures as they occur. Consistent with prior years, the Company uses the Black-Scholes option pricing model, which requires estimates of the expected term option holders will retain their options before exercising them and the estimated volatility of the Company’s common stock price over the expected term.

The Company recognized the full impact of its share-based employee payment plans in the statements of operations for each of the years ended December 31, 2025 and 2024 and did not capitalize any such costs on the balance sheets. The Company recognized $0.4 million of compensation expense related to stock options for the year ended December 31, 2025 and $0.4 million of compensation expense related to stock options for the

year ended December 31, 2024. The total compensation expense relating to vesting of stock options and stock issued for board service fees and other services for the year ended December 31, 2025 was $0.8 million and $0.4 million for the year ended December 31, 2024.

The fair value of each stock option is estimated at the date of grant using the Black-Scholes option pricing model. Assumptions regarding volatility, expected term, dividend yield and risk-free interest rate are required for the Black-Scholes model. The volatility assumption is based on the historical experience. The Company calculated expected term using the simplified method described in SEC Staff Accounting Bulletin, or SAB, No. 107 and No. 110.

Prepaid Expenses and Other Current Assets

Prepaid expenses and other current assets consist of amounts paid in advance for goods and services to be received in future periods. Such amounts are recorded at cost and amortized to expense over the period in which the related goods or services are received. The Company classifies prepaid amounts expected to be realized within twelve months as current assets and the remaining portion as non-current assets. The Company reviews prepaid balances for recoverability and records expense when it is determined that the future economic benefit is no longer probable. As of December 31, 2025, the Company’s prepaid balances included a multi-year insurance contract, of which $222 was classified in prepaid expenses and other current assets and $887 was classified in prepaid expenses and other non-current assets.

Net Loss per Share

Basic net loss per common share is computed by dividing net loss applicable to common stockholders by the weighted average number of shares of common stock outstanding for the period. Diluted net loss per share is computed using the weighted-average number of shares of common stock outstanding during the period, plus the dilutive effect of outstanding options and warrants, using the treasury stock method and the average market price of the Company’s common stock during the applicable period, unless their effect on net loss per share is antidilutive. The effect of computing diluted net loss per common share was antidilutive for any potentially issuable shares of common stock from the conversion of stock options, unvested restricted stock and warrants and, as such, have been excluded from the calculation.

Certain shares related to some of the Company’s outstanding common stock options and warrants have not been included in the computation of diluted net loss per share for the years ended December 31, 2025 and 2024 as the result would be antidilutive. Such potential common shares on December 31, 2025 and 2024 consist of the following:


	December 31,
	2025		2024
Common stock options		222,485		33,237
Warrants		106,452		26,552
Series A-1 Preferred Stock		181,159		-
Series A-2 Preferred Stock		189,309		-
		699,405		59,789


	For the years ended December 31,
	2025			2024
Net loss	$	(4,176	)	$	(4,679	)
Cumulative preferred dividends		(106	)		-
Net loss attributable to common stockholders	$	(4,282	)	$	(4,679	)

New Accounting Pronouncements

In December 2023, the Financial Accounting Standards Board (“FASB”) issued Accounting Standards Update (“ASU”) No. 2023-09, Income Taxes (Topic 740): Improvements to Income Tax Disclosures. ASU 2023-09 enhances income tax disclosures, including disclosures related to the rate reconciliation and income taxes paid. The amendments in ASU 2023-09 are effective for public business entities for annual periods beginning after December 15, 2024. The Company adopted ASU 2023-09 effective January 1, 2025 on a Prospective basis. The adoption of this guidance impacted the Company’s disclosures only and did not have a material effect on its consolidated financial position, results of operations, or cash flows.

In March 2024, the FASB issued ASU No. 2024-02, Codification Improvements—Amendments to Remove References to the Concept Statements. The amendments in ASU 2024-02 are effective for public business entities for fiscal years beginning after December 15, 2024. The Company adopted ASU 2024-02 effective January 1, 2025. The adoption of this standard did not have a material impact on the Company’s financial statements or related disclosures.

In December 2025, the FASB issued ASU No. 2025-11, Interim Reporting (Topic 270): Narrow-Scope Improvements. For public business entities, the amendments are effective for interim reporting periods within annual reporting periods beginning after December 15, 2027. The Company is evaluating the impact of this guidance. Because the amendments relate principally to interim reporting, the Company does not expect the standard to materially affect its annual financial statements, but adoption may affect the format and content of future interim disclosures.

In December 2025, the FASB issued ASU No. 2025-12, Codification Improvements. The amendments are effective for annual reporting periods beginning after December 15, 2026, and interim reporting periods within those annual reporting periods. The Company is evaluating the impact of this guidance and does not currently expect adoption to have a material impact on its financial statements.

Warrants - Additional Information (Details) $ / shares in Units, $ in Thousands	1 Months Ended	12 Months Ended
	May 31, 2025 USD ($) $ / shares shares	Dec. 31, 2025 $ / shares	Jun. 09, 2025 USD ($) yr	May 19, 2025	Dec. 31, 2024 $ / shares
Class of Warrant or Right [Line Items]
Warrant exercise per share \| $ / shares	$ 4	$ 9.63			$ 28.5
Fair value of the derivative liability \| $	$ 177		$ 31
Warrant Floor Price \| $ / shares		$ 0.57
Expected Volatility
Class of Warrant or Right [Line Items]
Warrant, measurement input			1.2581	1.1836
Risk-free Interest Rate
Class of Warrant or Right [Line Items]
Warrant, measurement input			0.0409	419
Dividend Rate
Class of Warrant or Right [Line Items]
Warrant, measurement input			0	0
Expected Term
Class of Warrant or Right [Line Items]
Warrant, measurement input			5	0.05
Share Price
Class of Warrant or Right [Line Items]
Warrant, measurement input			0.0312	0.0312
Excercise Price
Class of Warrant or Right [Line Items]
Warrant, measurement input			0.0336	0.0348
Equity Purchase Agreement
Class of Warrant or Right [Line Items]
Sale of Stock Description		In May 2025, the Company entered into an equity purchase agreement with an investor under which the Company has the option to sell up to $25.0 million of common stock over a period of 24 months at 97% of the prior trading day’s volume-weighted average price, subject to volume and ownership limitations. In connection with the agreement, the Company issued a warrant to purchase 79,900 shares of common stock at $4.00 per share, with a five-year term.
Sale Common Stock Period	24 months
Volume weighted average price percentage	97.00%
Equity Purchase Agreement \| Common Stock
Class of Warrant or Right [Line Items]
Warrants to purchase common stock \| shares	79,900
Equity Purchase Agreement \| Maximum [Member] \| Common Stock
Class of Warrant or Right [Line Items]
Sale of common stock \| $	$ 25,000

Income Taxes - Reconciliation of Income Tax Expense (Benefit) (Detail) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2025	Dec. 31, 2024
Income Tax Disclosure [Abstract]
Federal income tax at statutory rates, Amount	$ (859)
State income tax, net of federal tax benefit, Amount	196
Research and development credits, Amount	0
Research and development true-up, Amount	1,254
Stock-based compensation, Amount	18
Federal/state rate change, Amount	(914)
Change in valuation allowance, Amount	305
Effective tax rate, Amount	$ 0
Federal income tax at statutory rates	21.00%	21.00%
State income tax, net of federal tax benefit	(5.00%)	(2.00%)
Research and development credits	0.00%	0.00%
Research and development true-up	(31.00%)	29.00%
Stock-based compensation	0.00%	0.00%
Federal/state rate change	22.00%	0.00%
Change in valuation allowance	(7.00%)	(48.00%)
Effective tax rate	0.00%	0.00%

Employee Benefit Plan

12 Months Ended

Dec. 31, 2025

Postemployment Benefits [Abstract]

Employee Benefit Plan

10. Employee Benefit Plan

The Company sponsors a qualified 401(k) retirement plan under which employees are allowed to contribute certain percentages of their pay, up to the maximum allowed under Section 401(k) of the IRC, or the 401(k) Plan. The Company may make contributions to the 401(k) Plan at its discretion. The Company contributed approximately $13 and $0 to the 401(k) Plan during the year ended December 31, 2025 and 2024, respectively.

Organization - Additional Information (Details) - USD ($) $ in Thousands	Dec. 31, 2025	Dec. 31, 2024	Dec. 31, 2023
Cash, cash equivalents and restricted cash	$ 1,385	$ 1,091	$ 6,062
Accumulated deficit	$ 924,622	$ 920,446
Common stock, shares outstanding	2,349,480	1,601,252
Common Stock [Member]
Common stock, shares outstanding	2,349,480
Common stock reserved for future issuance	328,937

- Definition

Amount of accumulated undistributed earnings (deficit).

+ References + Details

Summary of Significant Accounting Policies

12 Months Ended

Dec. 31, 2025

Accounting Policies [Abstract]

Summary of Significant Accounting Policies

2. Summary of Significant Accounting Policies

Basis of Presentation

The accompanying financial statements have been prepared in accordance with accounting principles generally accepted in the United States of America (“U.S. GAAP”).

Use of Estimates

The Company’s most significant estimates and judgments used in the preparation of the financial statements are:

•

Clinical trial expenses and other research and development expenses;

•

Collaboration agreements;

•

Fair value measurements of stock-based compensation; and

•

Income taxes.

Cash and Cash Equivalents

Concentrations of Credit Risk

Property and Equipment


Office and computer equipment		3 years
Software		3 years
Laboratory equipment		5 years

Operating Segments

Warrants

Derivative Liabilities

Fair Value Measurements

•

Level 1—Quoted prices in active markets for identical assets or liabilities.

•

Level 3—Unobservable inputs that are supported by little or no market activity and that are significant to the fair value of the assets or liabilities.

Assets and liabilities measured at fair value on a recurring and nonrecurring basis as of December 31, 2025 and 2024 are as follows:


($ in thousands)			Fair Value Measurements at Reporting Date Using
Description	Balance as of December 31, 2025		Quoted Prices in Active Markets for Identical Assets/Liabilities (Level 1)		Significant Other Observable Inputs (Level 2)		Significant Unobservable Inputs (Level 3)
Cash equivalents	$	1,135	$	1,135	$	—	$	—


($ in thousands)			Fair Value Measurements at Reporting Date Using
Description	Balance as of December 31, 2024		Quoted Prices in Active Markets for Identical Assets/Liabilities (Level 1)		Significant Other Observable Inputs (Level 2)		Significant Unobservable Inputs (Level 3)
Cash equivalents	$	779	$	779	$	—	$	—

Revenue Recognition from Collaboration Agreements

Research and Development Costs

Income Taxes

Accounting for Stock-Based Compensation

Prepaid Expenses and Other Current Assets

Net Loss per Share


	December 31,
	2025		2024
Common stock options		222,485		33,237
Warrants		106,452		26,552
Series A-1 Preferred Stock		181,159		-
Series A-2 Preferred Stock		189,309		-
		699,405		59,789


	For the years ended December 31,
	2025			2024
Net loss	$	(4,176	)	$	(4,679	)
Cumulative preferred dividends		(106	)		-
Net loss attributable to common stockholders	$	(4,282	)	$	(4,679	)

New Accounting Pronouncements

Segment Information - Summary of Segment Reporting Information (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2025	Dec. 31, 2024	Dec. 31, 2023
Segment Reporting Information [Line Items]
Revenues	$ 5	$ 10
Less segment expenses:
Research and development	1,363	362
General and administrative	2,867	4,460
Change in fair value of warrant liability	(31)	0
Total operating expenses	4,230	4,822
Other income , net	80	133
Net loss	(4,176)	(4,679)	$ (4,679)
Operating Segments [Member]
Segment Reporting Information [Line Items]
Revenues	5	10
Less segment expenses:
Research and development	1,363	362
General and administrative	2,867	4,460
Change in fair value of warrant liability	(31)	0
Total operating expenses	4,230	4,822
Other income , net	80	133
Net loss	$ (4,176)	$ (4,679)

BALANCE SHEETS - USD ($) $ in Thousands	Dec. 31, 2025	Dec. 31, 2024
Current assets:
Cash and cash equivalents	$ 1,385	$ 1,091
Receivables	3	5
Prepaid expenses and other current assets, current	600	1,659
Total current assets	1,988	2,755
Property and equipment, net	91	0
Prepaid expenses and other assets, non current	887	0
Total assets	2,966	2,755
Current liabilities:
Accounts payable	613	516
Accrued expenses	200	176
Total current liabilities	813	692
Total liabilities	813	692
Commitments and contingencies (Note 5)
Stockholders' equity
Common stock $0.001 par value; 50,000,000 shares authorized, 2,349,480 and 1,601,252 shares issued and outstanding at December 31, 2025 and at December 31, 2024, respectively	2	2
Additional paid-in capital	926,773	922,507
Accumulated deficit	(924,622)	(920,446)
Total stockholders' equity	2,153	2,063
Total liabilities and stockholders' equity	2,966	2,755
Series A-1 Preferred Stock
Stockholders' equity
Preferred stock value	0	0
Series A-2 Preferred Stock
Stockholders' equity
Preferred stock value	$ 0	$ 0

STATEMENTS OF OPERATIONS - USD ($) $ in Thousands	12 Months Ended
STATEMENTS OF OPERATIONS - USD ($) $ in Thousands	Dec. 31, 2025	Dec. 31, 2024
Income Statement [Abstract]
Revenue	$ 5	$ 10
Operating expenses:
Research and development	1,363	362
General and administrative	2,867	4,460
Total operating expenses	4,230	4,822
Loss from operations	(4,225)	(4,812)
Other income (expense):
Change in fair value of warrant liability	(31)	0
Other income , net	80	133
Other income (expense), net	49	133
Net loss	$ (4,176)	$ (4,679)
Earnings per share, Basic	$ (2.2)	$ (2.92)
Earnings per share, Diluted	$ (2.2)	$ (2.92)
Weighted average common shares outstanding, basic	1,948,357	1,601,252
Weighted average common shares outstanding, diluted	1,948,357	1,601,252

Commitments and Contingencies

12 Months Ended

Dec. 31, 2025

Commitments and Contingencies Disclosure [Abstract]

Commitments and Contingencies

Exclusive License Agreement with Precigen

On April 3, 2023, the Company entered into the Amended and Restated Exclusive License Agreement with Precigen, or the A&R License Agreement, which restated and amended the parties' previous license agreement in full. Under the A&R License Agreement, the Company still had exclusive, worldwide rights to research, develop and commercialize TCR products designed for neoantigens or driver mutations for the treatment of cancer and non-exclusive rights to use non-driver mutation TCRs. On October 4, 2024, pursuant to Section 10.2 of the License Agreement, the Company duly notified Precigen of its full termination of all rights under the License Agreement.

The decision to terminate the A&R License Agreement was made after a thorough review of our strategic priorities and business objectives, including recognizing that the non-viral Sleeping Beauty gene transfer platform patent will expire in 2026. The Company continues to prosecute certain of the intellectual property underlying the TCRs targeting driver mutations such as KRAS, TP53 and EGFR, and the hunTR TCR discovery platform used in the discovery of our proprietary TCR library. The Company continues to explore strategic alternatives, including, but not limited to, an acquisition, merger, reverse merger, sale of assets, strategic partnerships, capital raises or other transactions.

License Agreement and Research and Development Agreement —The University of Texas MD Anderson Cancer Center

In 2015, the Company, together with Precigen, entered into a license agreement, or the MD Anderson License with MD Anderson (which Precigen subsequently assigned to PGEN). Pursuant to the MD Anderson License, the Company, together with Precigen, holds an exclusive, worldwide license to certain technologies owned and licensed by MD Anderson including technologies relating to novel CAR T-cell therapies, non-viral gene transfer systems, genetic modification and/or propagation of immune cells and other cellular therapy approaches, Natural Killer, or NK Cells, and TCRs.

In 2015, the Company, Precigen and MD Anderson entered into the 2015 R&D Agreement to formalize the scope and process for the transfer by MD Anderson, pursuant to the terms of the MD Anderson License, of certain existing research programs and related technology rights, as well as the terms and conditions for future collaborative research and development of new and ongoing research programs.

As provided under the MD Anderson License, the Company provided funding for research and development activities in support of the research programs under the 2015 R&D Agreement. At various times, the Company amended the 2015 R&D Agreement to extend the term until December 31, 2026 and in 2019 entered into the 2019 R&D Agreement, pursuant to which the Company agreed to collaborate with respect to the TCR program.

The 2019 R&D Agreement will terminate on December 31, 2026 and either party may terminate the 2019 R&D Agreement following written notice of a material breach. The 2019 R&D Agreement also contains customary provisions related to indemnification obligations, confidentiality and other matters.

During the reporting period, the Company continued to engage with The University of Texas M.D. Anderson Cancer Center (“MD Anderson”) to wind down the TCR trials. The parties completed the final reconciliation of amounts due under the related R&D agreements, and the Company received the final invoice during the second quarter of 2025. Amounts due to MD Anderson and recorded in accounts payable were $143 and $257 as of December 31, 2025 and 2024, respectively.

On November 4, 2025, the Office of the Attorney General of Texas, on behalf of MD Anderson, issued a demand for payment. On December 17, 2025, the Company entered into a Settlement and Release Agreement with MD Anderson to resolve the matter. Pursuant to the agreement, the Company agreed to pay $285 thousand in six installments through May 30, 2026, in full satisfaction of the outstanding invoices. The agreement also provides for mutual general releases, subject to customary exceptions, including for breach of the settlement agreement and certain ongoing matters such as Protocol 2006-0676.

Patent and Technology License Agreement—The University of Texas MD Anderson Cancer Center and the Texas A&M University System

In August 2004, the Company entered into a patent and technology license agreement with MD Anderson and the Texas A&M University System, which the Company refers to, collectively, as the Licensors. Under this agreement, the Company was granted an exclusive, worldwide license to rights (including rights to U.S. and foreign patent and patent applications and related improvements and know-how) for the manufacture and commercialization of two classes of organic arsenicals (water- and lipid-based) for human and animal use. The class of water-based organic arsenicals includes darinaparsin.

Under the terms of the agreement, the Company may be required to make payments to the Licensors upon achievement of certain milestones in varying amounts which, on a cumulative basis could total up to an additional $4.5 million. In addition, the Licensors are entitled to receive low single digit royalties on net sales from a licensed product and will also be entitled to receive a portion of any fees that the Company may receive from a possible sublicense under certain circumstances. During the years ended December 31, 2025 and 2024, the Company did not incur any milestone expenses or royalty expenses under this agreement.

Collaboration Agreement with Solasia Pharma K.K.

In 2011, the Company entered into a License and Collaboration Agreement with Solasia Pharma K. K., or Solasia, which was amended in 2014 to include an exclusive worldwide license and further amended in 2021 to revise certain payment schedule details, or, as so amended, the Solasia License and Collaboration Agreement. Pursuant to the Solasia License and Collaboration Agreement, the Company granted Solasia an exclusive license to develop and commercialize darinaparsin in both intravenous and oral forms and related organic arsenic molecules, in all indications for human use.

As consideration for the license, the Company is eligible to receive from Solasia development- and sales-based milestones, a royalty on net sales of darinaparsin, once commercialized, and a percentage of any sublicense revenue generated by Solasia.

During the years ended December 31, 2025 and 2024, the Company earned royalty revenue totaling $5 and $10, respectively, on net sales under this agreement.

Insurance Contract

During the year ended December 31, 2025 , the Company's insurance arrangement for certain risks which were previously paid in full began to be in force for a period of six years. Accordingly, the Company began amortizing the prepaid expense related to the contract. The Company has classified the prepaid contract between its current portion and long term-portion. As of December 31, 2025, $222 is included in prepaid expenses and other current assets and $887 is included in prepaid expense and other non-current assets in the accompanying balance sheet.

Director Resignation

On April 15, 2025, Dr. Robert Hofmeister, Ph.D. resigned as a member of the Board of Directors of the Company with immediate effect. Dr. Robert Hofmeister's, Ph.D. resignation was not the result of any disagreement on any matter relating to the Company’s operations, policies or practices.

Changes in Corporate Governance

On July 1, 2025, Dale Curtis Hogue, Jr. resigned from his positions as Chief Executive Officer and a member of the Board of Directors of the Company, effective immediately. His resignation was not due to any disagreement with the Company. In connection with his departure, the Company entered into a Consulting Agreement with Mr. Hogue, effective July 1, 2025, under which he will provide strategic and advisory services to the Company at a rate of $250 per hour. The agreement remains in effect until terminated by either party.

On July 2, 2025, the Board appointed Holger Weis as Chief Executive Officer, effective immediately. Mr. Weis will continue to serve as Chair of the Board of Directors, but has relinquished his roles on the Audit and Compensation Committees, pursuant to applicable Nasdaq Listing Rules. In connection with his appointment, the Company entered into an Employment Agreement with Mr. Weis, providing for an annual base salary of $275 and a stock option to purchase 130,000 shares of common stock at an exercise price of $5.06 per share. One-quarter of the option vested immediately, with the remainder vesting in equal quarterly installments over three years.

On July 15, 2025, the Board of Directors of the Company appointed Mr. Michael A. Jerman as an independent director of the Company, effective immediately, to fill the vacancy on the Board of Directors created by the resignation of Mr. Hogue and the vacancies on the audit and compensation committees from Mr. Weis’s appointment as CEO. In connection with his appointment, Mr. Jerman was also named to the Audit Committee and the Compensation Committee of the Board, and will serve as the Chair of the Audit Committee. Upon his appointment, Mr. Jerman was awarded options to purchase Common Stock pursuant to the Company's Non-employee Director Compensation Policy.

On July 16, 2025, Melinda Lackey notified the Company of her decision to terminate the Consulting Agreement dated November 14, 2023 (the “Agreement”) pursuant to terms of the agreement, with such termination to be effective 30 days from the date of notice, or August 15, 2025. In

connection with the termination of the Agreement, Ms. Lackey resigned from her roles as Legal and Administrative Officer and Corporate Secretary of the Company as of the effective Date. Ms. Lackey’s departure is not the result of any disagreement with the Company on any matter relating to the Company’s operations, policies, or practices.

On August 14, 2025, the Board of Directors of the Company appointed Mr. Ferdinand Groenewald as Corporate Secretary effective upon the resignation of Ms. Lackey.

Sales Tax Contingency

The Company is subject to examination by certain state and local taxing authorities related to sales and use tax matters. The Company records a liability for such matters when it is probable that a liability has been incurred and the amount can be reasonably estimated. As of December 31, 2025, the Company has recorded an estimated liability of $54 to these matters. In addition, the Company may be exposed to additional loss; however, the Company cannot reasonably estimate the amount or range of additional loss at this time.

Property and Equipment, net

12 Months Ended

Dec. 31, 2025

Property, Plant and Equipment [Abstract]

Property and Equipment, net

Property and equipment, net, consists of the following:


	December 31,			December 31,
($ in thousands)	2025			2024
Office and computer equipment	$	-		$	15
Laboratory equipment		98			-
		98			15
Less: accumulated depreciation		(7	)		(15	)
Property and equipment, net	$	91		$	-

Depreciation expense for the year ended December 31, 2025 and 2024 was $7 and was $2, respectively.

Subsequent Events

12 Months Ended

Dec. 31, 2025

Subsequent Events [Abstract]

Subsequent Events

12. Subsequent Events

The Company evaluated all events and transactions that occurred after the balance sheet date through the date of this Annual Report on Form 10-K. Other than as described in the notes to the financial statements, the Company did not have any material subsequent events that impacted its financial statements or disclosures.

Director Compensation

On January 12, 2026, members of the Board of Directors of the Company elected to receive compensation in equity rather than in cash for their fourth quarter board service fees. Accordingly, the Company issued 16,867 shares of common stock with an aggregate fair value of $49.

Accrued Expenses - Component of Accrued Expenses (Details) - USD ($) $ in Thousands	Dec. 31, 2025	Dec. 31, 2024
Payables and Accruals [Abstract]
Preclinical services	$ 123	$ 97
Sales and use taxes	54	0
Professional services	23	79
Total	$ 200	$ 176

Summary of Significant Accounting Policies - Potential Dilutive Shares Excluded from Computation of Diluted Net Loss Per Share (Detail) - shares	12 Months Ended
	Dec. 31, 2025	Dec. 31, 2024
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Antidilutive securities excluded from computation of earnings per share, amount	699,405	59,789
Series A-1 Preferred Stock [Member]
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Antidilutive securities excluded from computation of earnings per share, amount	181,159
Series A-2 Preferred Stock [Member]
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Antidilutive securities excluded from computation of earnings per share, amount	189,309
Warrants [Member]
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Antidilutive securities excluded from computation of earnings per share, amount	106,452	26,552
Common stock options [Member]
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Antidilutive securities excluded from computation of earnings per share, amount	222,485	33,237

Organization

12 Months Ended

Dec. 31, 2025

Accounting Policies [Abstract]

Organization

Alaunos Therapeutics, Inc., which is referred to herein as “Alaunos,” or the “Company,” is a pre-clinical stage obesity and metabolic disorders company with a current focus on developing oral small molecules for obesity and other metabolic disorders. The Company was historically involved in the development of adoptive TCR therapies, designed to treat multiple solid tumor types in large cancer patient populations with unmet clinical needs.

The Company’s operations to date have consisted primarily of conducting research and development and raising capital to fund those efforts.

As of December 31, 2025 there were 2,349,480 shares of common stock outstanding and an additional 328,937 shares of common stock reserved for issuance pursuant to outstanding stock options and warrants.

The accompanying financial statements have been prepared on a going concern basis, which contemplates the realization of assets and satisfaction of liabilities and commitments in the normal course of business.

Liquidity and Going Concern

The Company has operated at a loss since its inception in 2003 and has minimal recurring revenue from operations. The Company anticipates that losses will continue for the foreseeable future. As of December 31, 2025, the Company had approximately $1.4 million of cash and cash equivalents. The Company’s accumulated deficit at December 31, 2025 was approximately $924.6 million. Given its current development plans and cash management efforts, the Company anticipates cash resources will be sufficient to fund operations into the second quarter of 2026. The Company’s ability to continue operations after its current cash resources are exhausted depends on future events including its ability to obtain additional financing or to achieve profitable results, as to which no assurances can be given. If adequate additional funds are not available when required, management may need to curtail its development efforts and planned operations to conserve cash until sufficient additional capital is raised. There can be no assurances that such a plan would be successful.

Based on the current cash forecast and the Company's dependence on its ability to obtain additional financing to fund its operations after the current resources are exhausted, about which there can be no certainty, management has determined that the Company's present capital resources will not be sufficient to fund its planned operations for at least one year from the issuance date of the financial statements which raises substantial doubt as to the Company's ability to continue as a going concern. This forecast of cash resources is forward-looking information that involves risks and uncertainties, and the actual amount of expenses could vary materially and adversely as a result of a number of factors.

Cybersecurity Risk Management, Strategy and Governance	12 Months Ended
Cybersecurity Risk Management, Strategy and Governance	Dec. 31, 2025
Cybersecurity Risk Management, Strategy, and Governance [Line Items]
Cybersecurity Risk Management Processes for Assessing, Identifying, and Managing Threats [Text Block]	Item 1C. Cybersecurity Cybersecurity Program We have implemented a cybersecurity program designed to support the effectiveness of our systems and our preparedness for information security risks. This program includes safeguards, such as: password protection; multi-factor authentication; monitoring and alerting systems for internal and external threats; and regular evaluations of our cybersecurity program. We use a risk-based approach with respect to our use and oversight of third-party service providers, tailoring processes according to the nature and sensitivity of the data accessed, processed, or stored by such third-party service provider. We also seek to include appropriate security terms in our contracts, where applicable as part of our oversight of third-party providers. Process for Assessing, Identifying and Managing Material Risks from Cybersecurity Threats We maintain an incident response program. In the event of a cybersecurity incident, designated personnel are responsible for assessing the severity of an incident and associated threat, containing the threat, remediating the threat, including recovery of data and access to systems, analyzing any reporting obligations associated with the incident, and performing post-incident analysis and program enhancements. We maintain an Incident Response Plan, which includes an Incident Response Process in the event of a significant cybersecurity incident. In the event of a significant cybersecurity incident, our head of administration will chair an incident response team to handle the incident. Such incident response team will include members of IT, finance (if applicable), legal, communications, human resources and any affected unit or department. IT, along with a designated forensic team, will use the Incident Response Process to guide the response. Governance Management Oversight The controls and processes employed to assess, identify and manage material risks from cybersecurity threats are implemented and overseen by our VP of Finance and our managed service provider. Our VP of Finance is responsible for the day-to-day management of the cybersecurity program, including the prevention, detection, investigation, response to, and recovery from cybersecurity threats and incidents, and is regularly engaged to help ensure the cybersecurity program functions effectively in the face of evolving cybersecurity threats. Our VP of Finance oversees the Incident Response Plan and briefs our board of directors on cybersecurity matters, including the nature and design of our cybersecurity program, and threats, events, and program enhancements. Board Oversight In its oversight role, our Board of Directors is expected to specifically consider risks, including with respect to privacy, information technology and cybersecurity and threats to technology infrastructure. On a regular basis, the VP of Finance reports to our Board of Directors on cybersecurity matters, including key risks, the potential impact of those exposures on our business, financial condition, results of operations, cash flows and prospects, and the programs and steps implemented by our management team to monitor and mitigate risks. Cybersecurity Risks Our cybersecurity risk management processes are integrated into our overall approach to risk management. Given our nature and size, we do not have a dedicated enterprise risk function, but our management team regularly considers and evaluates risks. As part of that risk management process, our management team identifies, assesses and evaluates risks impacting our operations, including those risks related to cybersecurity, and raises them for internal discussion, and where it is determined to be appropriate, issues are also raised to our Board of Directors for consideration. As of the date of this Annual Report on Form 10-K, we are not aware of any previous cybersecurity incidents that have materially affected or are reasonably likely to materially affect our business, financial condition, results of operations, cash flows and prospects. While we have implemented a cybersecurity program, the techniques used to infiltrate information technology systems continue to evolve. Accordingly, we may not be able to timely detect threats or anticipate and implement adequate security measures. For additional information regarding risks relating to privacy and cybersecurity, see "Item IA—Risk Factors—Risks Related to Our Business."
Cybersecurity Risk Management Processes Integrated [Flag]	true
Cybersecurity Risk Management Processes Integrated [Text Block]	Our cybersecurity risk management processes are integrated into our overall approach to risk management. Given our nature and size, we do not have a dedicated enterprise risk function, but our management team regularly considers and evaluates risks. As part of that risk management process, our management team identifies, assesses and evaluates risks impacting our operations, including those risks related to cybersecurity, and raises them for internal discussion, and where it is determined to be appropriate, issues are also raised to our Board of Directors for consideration. As of the date of this Annual Report on Form 10-K, we are not aware of any previous cybersecurity incidents that have materially affected or are reasonably likely to materially affect our business, financial condition, results of operations, cash flows and prospects. While we have implemented a cybersecurity program, the techniques used to infiltrate information technology systems continue to evolve. Accordingly, we may not be able to timely detect threats or anticipate and implement adequate security measures. For additional information regarding risks relating to privacy and cybersecurity, see "Item IA—Risk Factors—Risks Related to Our Business."
Cybersecurity Risk Management Third Party Engaged [Flag]	true
Cybersecurity Risk Third Party Oversight and Identification Processes [Flag]	true
Cybersecurity Risk Materially Affected or Reasonably Likely to Materially Affect Registrant [Flag]	false
Cybersecurity Risk Board of Directors Oversight [Text Block]	Management Oversight The controls and processes employed to assess, identify and manage material risks from cybersecurity threats are implemented and overseen by our VP of Finance and our managed service provider. Our VP of Finance is responsible for the day-to-day management of the cybersecurity program, including the prevention, detection, investigation, response to, and recovery from cybersecurity threats and incidents, and is regularly engaged to help ensure the cybersecurity program functions effectively in the face of evolving cybersecurity threats. Our VP of Finance oversees the Incident Response Plan and briefs our board of directors on cybersecurity matters, including the nature and design of our cybersecurity program, and threats, events, and program enhancements. Board Oversight In its oversight role, our Board of Directors is expected to specifically consider risks, including with respect to privacy, information technology and cybersecurity and threats to technology infrastructure. On a regular basis, the VP of Finance reports to our Board of Directors on cybersecurity matters, including key risks, the potential impact of those exposures on our business, financial condition, results of operations, cash flows and prospects, and the programs and steps implemented by our management team to monitor and mitigate risks.
Cybersecurity Risk Board Committee or Subcommittee Responsible for Oversight [Text Block]	In its oversight role, our Board of Directors is expected to specifically consider risks, including with respect to privacy, information technology and cybersecurity and threats to technology infrastructure. On a regular basis, the VP of Finance reports to our Board of Directors on cybersecurity matters, including key risks, the potential impact of those exposures on our business, financial condition, results of operations, cash flows and prospects, and the programs and steps implemented by our management team to monitor and mitigate risks.
Cybersecurity Risk Process for Informing Board Committee or Subcommittee Responsible for Oversight [Text Block]	Our VP of Finance oversees the Incident Response Plan and briefs our board of directors on cybersecurity matters, including the nature and design of our cybersecurity program, and threats, events, and program enhancements.
Cybersecurity Risk Role of Management [Text Block]	Management Oversight The controls and processes employed to assess, identify and manage material risks from cybersecurity threats are implemented and overseen by our VP of Finance and our managed service provider. Our VP of Finance is responsible for the day-to-day management of the cybersecurity program, including the prevention, detection, investigation, response to, and recovery from cybersecurity threats and incidents, and is regularly engaged to help ensure the cybersecurity program functions effectively in the face of evolving cybersecurity threats. Our VP of Finance oversees the Incident Response Plan and briefs our board of directors on cybersecurity matters, including the nature and design of our cybersecurity program, and threats, events, and program enhancements.
Cybersecurity Risk Management Positions or Committees Responsible [Flag]	true
Cybersecurity Risk Management Positions or Committees Responsible [Text Block]	The controls and processes employed to assess, identify and manage material risks from cybersecurity threats are implemented and overseen by our VP of Finance and our managed service provider. Our VP of Finance is responsible for the day-to-day management of the cybersecurity program, including the prevention, detection, investigation, response to, and recovery from cybersecurity threats and incidents, and is regularly engaged to help ensure the cybersecurity program functions effectively in the face of evolving cybersecurity threats.
Cybersecurity Risk Process for Informing Management or Committees Responsible [Text Block]	We maintain an incident response program. In the event of a cybersecurity incident, designated personnel are responsible for assessing the severity of an incident and associated threat, containing the threat, remediating the threat, including recovery of data and access to systems, analyzing any reporting obligations associated with the incident, and performing post-incident analysis and program enhancements. We maintain an Incident Response Plan, which includes an Incident Response Process in the event of a significant cybersecurity incident. In the event of a significant cybersecurity incident, our head of administration will chair an incident response team to handle the incident. Such incident response team will include members of IT, finance (if applicable), legal, communications, human resources and any affected unit or department. IT, along with a designated forensic team, will use the Incident Response Process to guide the response
Cybersecurity Risk Management Positions or Committees Responsible Report to Board [Flag]	true

STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands	12 Months Ended
STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands	Dec. 31, 2025	Dec. 31, 2024
Cash flows from operating activities:
Net loss	$ (4,176)	$ (4,679)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation	7	2
Change in fair value of warrant liability	31	0
Common stock issued for services rendered	382	0
Stock-based compensation	414	435
Changes in operating assets and liabilities:
Receivables	2	(4)
Prepaid expenses and other current assets	350	539
Accounts payable	97	(100)
Accrued expenses	24	(1,164)
Net cash flows from operating activities	(2,869)	(4,971)
Cash flows from investing activities:
Purchases of property and equipment	(98)	0
Net cash flows from investing activities	(98)	0
Cash flows from financing activities:
Proceeds from the issuance of common stock and pre funded warrants, net of offering costs	1,911	0
Proceeds from sale of Series A-1 preferred stock	500	0
Proceeds from sale of Series A-2 preferred stock	850	0
Net cash flows from financing activities	3,261	0
Net increase (decrease) in cash, cash equivalents	294	(4,971)
Cash and cash equivalents, beginning of period	1,091	6,062
Cash and cash equivalents, end of period	1,385	1,091
Supplementary disclosure of cash flow information:
Cash paid for interest	0	0
Noncash financing activities:
Recognition of warrant liability in connection with the equity line of credit agreement	178	0
Amounts included in accrued expenses and accounts payable related to property and equipment	$ 67	$ 0

BALANCE SHEETS (Parenthetical) - $ / shares	Dec. 31, 2025	Dec. 31, 2024
Common stock, par value	$ 0.001	$ 0.001
Common stock, shares authorized	50,000,000	50,000,000
Common stock, shares issued	2,349,480	1,601,252
Common stock, shares outstanding	2,349,480	1,601,252
Series A-1 Preferred Stock
Preferred stock, par value	$ 0.001	$ 0.001
Preferred stock, shares authorized	1,000	1,000
Preferred stock, shares issued	500	0
Preferred stock, shares outstanding	500	0
Series A-2 Preferred Stock
Preferred stock, par value	$ 0.001	$ 0.001
Preferred stock, shares authorized	1,000	1,000
Preferred stock, shares issued	850	0
Preferred stock, shares outstanding	850	0

Income Taxes (Tables)

12 Months Ended

Dec. 31, 2025

Income Tax Disclosure [Abstract]

Significant Component of Deferred Tax Assets

Significant components of the Company’s deferred tax assets at December 31, 2025 and 2024 are as follows:


	December 31,
(in thousands)	2025			2024
Deferred tax assets:
Net operating loss carryforwards	$	163,254		$	154,634
Start-up and pre-clinical studies		8,683			11,011
Research and development credit carryforwards		40,345			40,486
Stock-based compensation		766			699
Capitalized acquisition costs		556			1,050
Lease liability		—			—
Depreciation		0			1
Capitalized research expenses		0			5,400
Other		(20	)		0
		213,584			213,281
Less valuation allowance		(213,584	)		(213,281	)
Total deferred tax assets		—			—

Right-of-use asset		—			—
Total deferred tax liabilities	$	—		$	—
Net deferred taxes	$	—		$	—

Reconciliation of Income Tax Expense (Benefit)

A reconciliation of the U.S. federal statutory income tax expense (benefit) to our effective tax rate pursuant to the disclosure requirements of ASU 2023-09 for the year ended December 31, 2025 is as follows:


	Year Ended December 31,
(in thousands)	2025
Federal income tax at statutory rates	$	(859	)		21	%
State income tax, net of federal tax benefit		196			(5	)%
Research and development credits		-		— %
Research and development true-up		1,254			(31	)%
Stock-based compensation		18		— %
Federal/state rate change		(914	)		22	%
Change in valuation allowance		305			(7	)%
Effective tax rate	$	-			0	%

A reconciliation of the U.S. federal statutory income tax expense (benefit) to our effective tax rate for the years ended December 31, 2024 is as follows (in percentages):


	Year Ended December 31,
(in thousands)	2024
Federal income tax at statutory rates		21	%
State income tax, net of federal tax benefit		(2	)%
Research and development credits	— %
Research and development true-up		29	%
Stock-based compensation	— %
Federal/state rate change		0	%
Change in valuation allowance		(48	)%
Effective tax rate		—	%

Accrued Expenses (Tables)

12 Months Ended

Dec. 31, 2025

Payables and Accruals [Abstract]

Component of Accrued Expenses

Accrued expenses consist of the following:


($ in thousands)	2025		2024
Preclinical services	$	123	$	97
Sales and use taxes		54		-
Professional services		23		79
	$	200	$	176

Income Taxes

12 Months Ended

Dec. 31, 2025

Income Tax Disclosure [Abstract]

Income Taxes

There is no provision for income taxes because the Company has incurred operating losses since inception. The reported amounts of income tax expense for the years ended December 31, 2025 and 2024 differ from the amounts that would result from applying domestic federal statutory tax

rates to pretax losses primarily because of the changes in the valuation allowance. Significant components of the Company’s deferred tax assets at December 31, 2025 and 2024 are as follows:


	December 31,
(in thousands)	2025			2024
Deferred tax assets:
Net operating loss carryforwards	$	163,254		$	154,634
Start-up and pre-clinical studies		8,683			11,011
Research and development credit carryforwards		40,345			40,486
Stock-based compensation		766			699
Capitalized acquisition costs		556			1,050
Lease liability		—			—
Depreciation		0			1
Capitalized research expenses		0			5,400
Other		(20	)		0
		213,584			213,281
Less valuation allowance		(213,584	)		(213,281	)
Total deferred tax assets		—			—

Right-of-use asset		—			—
Total deferred tax liabilities	$	—		$	—
Net deferred taxes	$	—		$	—

Deferred income taxes reflect the net tax effects of temporary differences between the carrying amount of assets and liabilities for financial reporting purposes and the amounts used for income tax purposes. At December 31, 2025, the Company has aggregate net operating loss carryforwards for federal tax purposes of approximately $775 million, of which approximately $339 million expire at various dates through December 31, 2037 and approximately $436 million can be carried forward indefinitely. The Company has generated a gross net operating loss of approximate $10.9 million in Florida for the current year. The Company is reducing its approximately $498 million of state net operating loss carryforwards to $0 as these state net operating loss carryforwards all related to Massachusetts filings and, as of December 31, 2024 the Company no longer had any employees or property in Massachusetts and, as a result, the Company will no longer have income tax nexus in Massachusetts or an income tax filing obligation after the year ended December 31, 2024. Additionally, the Company has approximately $40.3 million of federal and state research and development credits at December 31, 2025, expiring in varying amounts through 2045, which may be available to reduce future taxes. The Company has reduced its Massachusetts credits carryforward to $0 as well at December 31, 2024.

The Company has provided a valuation allowance for the full amount of its net deferred tax assets since it is more likely than not that these future benefits will not be realized. However, these deferred tax assets may be available to offset future income tax liabilities and expenses. The valuation allowance increased by $303 in 2025 due primarily to net operating loss carryforwards and the increase in research and development credits.

Income taxes using the federal statutory income tax rate differ from the Company’s effective tax rate primarily due to non-deductible expenses related to the Company’s issuance of warrants along with the change in the valuation allowance on deferred tax assets.

Beginning in 2025 annual reporting, we adopted ASU 2023-09 prospectively. See Note 2 — Summary of Significant Accounting Policies – Recently Adopted Accounting Pronouncements for additional details on the adoption of ASU 2023-09. A reconciliation of the U.S. federal statutory income tax expense (benefit) to our effective tax rate pursuant to the disclosure requirements of ASU 2023-09 for the year ended December 31, 2025 is as follows:


	Year Ended December 31,
(in thousands)	2025
Federal income tax at statutory rates	$	(859	)		21	%
State income tax, net of federal tax benefit		196			(5	)%
Research and development credits		-		— %
Research and development true-up		1,254			(31	)%
Stock-based compensation		18		— %
Federal/state rate change		(914	)		22	%
Change in valuation allowance		305			(7	)%
Effective tax rate	$	-			0	%

A reconciliation of the U.S. federal statutory income tax expense (benefit) to our effective tax rate for the years ended December 31, 2024 is as follows (in percentages):


	Year Ended December 31,
(in thousands)	2024
Federal income tax at statutory rates		21	%
State income tax, net of federal tax benefit		(2	)%
Research and development credits	— %
Research and development true-up		29	%
Stock-based compensation	— %
Federal/state rate change		0	%
Change in valuation allowance		(48	)%
Effective tax rate		—	%

The Company adopted ASC 740, Accounting for Uncertain Tax Positions on January 1, 2007. ASC 740 clarifies the accounting for uncertainty in income taxes recognized in an enterprise’s financial statements in accordance with FASB Statement No. 109, “Accounting for Income Taxes.” ASC 740 prescribes a recognition threshold and measurement of a tax position taken or expected to be taken in a tax return. The Company did not establish any additional reserves for uncertain tax liabilities upon adoption of ASC 740. There were no adjustments to its uncertain tax positions in the years ended December 31, 2025 and 2024.

The Company has not recognized any interest and penalties in the statements of operations because of the Company’s net operating losses and tax credits that are available to be carried forward. When necessary, the Company will account for interest and penalties related to uncertain tax positions as part of its provision for federal and state income taxes. The Company does not expect the amounts of unrecognized benefits will change significantly within the next twelve months.

- Definition

The entire disclosure for income tax.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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-Section 50
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Reference 2: http://www.xbrl.org/2003/role/disclosureRef
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Reference 3: http://www.xbrl.org/2003/role/disclosureRef
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-Publisher FASB
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Reference 4: http://www.xbrl.org/2003/role/disclosureRef
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Reference 5: http://www.xbrl.org/2003/role/exampleRef
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-Section 55
-Paragraph 231
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482663/740-10-55-231

Reference 6: http://www.xbrl.org/2003/role/disclosureRef
-Topic 740
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 12C
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482685/740-10-50-12C

Reference 7: http://www.xbrl.org/2003/role/disclosureRef
-Topic 740
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 12B
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482685/740-10-50-12B

Reference 8: http://www.xbrl.org/2003/role/disclosureRef
-Topic 740
-SubTopic 270
-Name Accounting Standards Codification
-Section 50
-Paragraph 1
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147477891/740-270-50-1

Reference 9: http://www.xbrl.org/2003/role/disclosureRef
-Topic 740
-SubTopic 10
-Name Accounting Standards Codification
-Section S99
-Paragraph 1
-Subparagraph (SAB Topic 6.I.5.Q1)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147479360/740-10-S99-1

Reference 10: http://www.xbrl.org/2003/role/disclosureRef
-Topic 946
-SubTopic 20
-Name Accounting Standards Codification
-Section 50
-Paragraph 13
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147480990/946-20-50-13

Reference 11: http://www.xbrl.org/2003/role/disclosureRef
-Topic 235
-SubTopic 10
-Name Accounting Standards Codification
-Section S99
-Paragraph 1
-Subparagraph (SX 210.4-08(h)(2))
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+ Details

Warrants (Tables)

12 Months Ended

Dec. 31, 2025

Warrants Disclosure [Abstract]

Summary of Warrant Activity

The following is a summary of the Company's warrant activity for the years ended December 31, 2025:


(in thousands, except share and per share data)	Number of Shares			Weighted- Average Exercise Price		Weighted- Average Contractual Term (Years)
Outstanding, December 31, 2024		26,552		$	28.50	2.75
Granted		351,574			0.76
Exercised		(271,674	)		0.001
Outstanding, December 31, 2025		106,452		$	9.63		3.73

STATEMENTS OF CHANGES IN STOCKHOLDERS' EQUITY - USD ($) $ in Thousands	Total	Common Stock	Preferred Stock Series A-1 Preferred Stock	Preferred Stock Series A-2 Preferred Stock	Additional Paid In Capital	Accumulated Deficit
Balance at Dec. 31, 2023	$ 6,307	$ 2			$ 922,072	$ (915,767)
Balance (in shares) at Dec. 31, 2023		1,601,252
Stock-based compensation	435				435
Net loss	(4,679)					(4,679)
Balance at Dec. 31, 2024	2,063	$ 2			922,507	(920,446)
Balance (in shares) at Dec. 31, 2024		1,601,252
Stock-based compensation	414				414
Shares issued as consideration for board service fees ( in shares)		60,384
Shares issued as consideration for board service fees	195				195
Shares issued as consideration for services (in shares)		77,463
Shares issued as consideration for services	187				187
Sale of Series A-1 preferred stock (in shares)			500
Sale of Series A-1 preferred stock	500				500
Issuance of common stock in registered direct offering, net of offering costs (in shares)		338,725
Issuance of common stock in registered direct offering, net of offering costs	998				998
Issuance of prefunded warrants in registered direct offering	913				913
Reclassification of Warrant Liability to equity	209				209
Exercise of prefunded warrants		271,656
Sale of Series A-2 preferred stock (in shares)				850
Sale of Series A-2 preferred stock	850				850
Net loss	(4,176)					(4,176)
Balance at Dec. 31, 2025	$ 2,153	$ 2			$ 926,773	$ (924,622)
Balance (in shares) at Dec. 31, 2025		2,349,480	500	850

Summary of Significant Accounting Policies - Assets and Liabilities Measured at Fair Value on Recurring Basis (Details) - Fair Value, Measurements, Recurring [Member] - USD ($) $ in Thousands	Dec. 31, 2025	Dec. 31, 2024
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Cash equivalents	$ 1,135	$ 779
Quoted Prices in Active Markets for Identical Assets/Liabilities (Level 1) [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Cash equivalents	$ 1,135	$ 779

Segment Information

12 Months Ended

Dec. 31, 2025

Segment Reporting [Abstract]

Segment Information

11. Segment Information

The CODM for the Company is the Chief Executive Officer (the "CEO"). The Company’s CEO reviews operating results on an aggregate basis and manages the Company’s operations as a whole for the purpose of evaluating financial performance and allocating resources. This decision-making process reflects the way in which financial information is regularly reviewed and used by the CODM to evaluate performance, set operational targets, forecast future financial results, and allocate resources. Accordingly, the Company has determined that it has a single reportable and operating segment related to biopharmaceutical research and development.

The Company’s CODM assesses financial performance and allocates resources based on operating results which are also reported on the statements of operations. The measure of segment assets is reported on the balance sheet as total assets. The CODM utilizes combined operating

results by comparing actual results against budgeted amounts. As part of this process, net loss is a critical performance measure used to evaluate the Company’s operating performance and guide strategic decisions and resource allocations, including additional investments in research and development. The table below provides information about the Company’s revenue, significant segment expenses and other segment expenses.

The table below provides information about the Company’s revenue, significant segment expenses and other segment expenses.


	For the years ended December 31,
($ in thousands)	2025			2024
Revenues	$	5		$	10
Less segment expenses:
Research and development		1,363				362
General and administrative		2,867				4,460
Total operating and segment expense		4,230				4,822
Plus:
Change in fair value of warrant liability		(31	)			-
Other income, net		80				133
Segment Net loss	$	(4,176	)	$		(4,679	)

- Definition

The entire disclosure for reporting segments including data and tables. Reportable segments include those that meet any of the following quantitative thresholds a) it's reported revenue, including sales to external customers and intersegment sales or transfers is 10 percent or more of the combined revenue, internal and external, of all operating segments b) the absolute amount of its reported profit or loss is 10 percent or more of the greater, in absolute amount of 1) the combined reported profit of all operating segments that did not report a loss or 2) the combined reported loss of all operating segments that did report a loss c) its assets are 10 percent or more of the combined assets of all operating segments.

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+ Details