100000 - Document - Cover Page link:presentationLink link:calculationLink link:definitionLink 100010 - Statement - BALANCE SHEETS link:presentationLink link:calculationLink link:definitionLink 100020 - Disclosure - Leases - Operating Lease Liabilities (Details) 2 link:presentationLink link:calculationLink link:definitionLink 100030 - Statement - BALANCE SHEETS (Parenthetical) link:presentationLink link:calculationLink link:definitionLink 100040 - Statement - STATEMENTS OF OPERATIONS link:presentationLink link:calculationLink link:definitionLink 100050 - Statement - STATEMENTS OF CHANGES IN STOCKHOLDERS' EQUITY link:presentationLink link:calculationLink link:definitionLink 100060 - Statement - STATEMENTS OF CHANGES IN STOCKHOLDERS' EQUITY (Parenthetical) link:presentationLink link:calculationLink link:definitionLink 100070 - Statement - STATEMENTS OF CASH FLOWS link:presentationLink link:calculationLink link:definitionLink 100080 - Disclosure - Organization link:presentationLink link:calculationLink link:definitionLink 100090 - Disclosure - Financings link:presentationLink link:calculationLink link:definitionLink 100100 - Disclosure - Summary of Significant Accounting Policies link:presentationLink link:calculationLink link:definitionLink 100110 - Disclosure - Debt link:presentationLink link:calculationLink link:definitionLink 100120 - Disclosure - Property and Equipment, net link:presentationLink link:calculationLink link:definitionLink 100130 - Disclosure - Accrued Expenses link:presentationLink link:calculationLink link:definitionLink 100140 - Disclosure - Related Party Transactions link:presentationLink link:calculationLink link:definitionLink 100150 - Disclosure - Settlement of a Related Party Relationship link:presentationLink link:calculationLink link:definitionLink 100160 - Disclosure - Leases link:presentationLink link:calculationLink link:definitionLink 100170 - Disclosure - Commitments and Contingencies link:presentationLink link:calculationLink link:definitionLink 100180 - Disclosure - Warrants link:presentationLink link:calculationLink link:definitionLink 100190 - Disclosure - Restructuring link:presentationLink link:calculationLink link:definitionLink 100200 - Disclosure - Income Taxes link:presentationLink link:calculationLink link:definitionLink 100210 - Disclosure - Preferred Stock and Stockholders' Equity (Deficit) link:presentationLink link:calculationLink link:definitionLink 100220 - Disclosure - Derivative Financial Instruments link:presentationLink link:calculationLink link:definitionLink 100230 - Disclosure - Stock Option Plan link:presentationLink link:calculationLink link:definitionLink 100240 - Disclosure - Employee Benefit Plan link:presentationLink link:calculationLink link:definitionLink 100250 - Disclosure - Joint Venture link:presentationLink link:calculationLink link:definitionLink 100260 - Disclosure - Summary of Significant Accounting Policies (Policies) link:presentationLink link:calculationLink link:definitionLink 100270 - Disclosure - Summary of Significant Accounting Policies (Tables) link:presentationLink link:calculationLink link:definitionLink 100280 - Disclosure - Debt (Tables) link:presentationLink link:calculationLink link:definitionLink 100290 - Disclosure - Property and Equipment, net (Tables) link:presentationLink link:calculationLink link:definitionLink 100300 - Disclosure - Accrued Expenses (Tables) link:presentationLink link:calculationLink link:definitionLink 100310 - Disclosure - Leases (Tables) link:presentationLink link:calculationLink link:definitionLink 100320 - Disclosure - Restructuring (Tables) link:presentationLink link:calculationLink link:definitionLink 100330 - Disclosure - Income Taxes (Tables) link:presentationLink link:calculationLink link:definitionLink 100340 - Disclosure - Derivative Financial Instruments (Tables) link:presentationLink link:calculationLink link:definitionLink 100350 - Disclosure - Stock Option Plans (Tables) link:presentationLink link:calculationLink link:definitionLink 100360 - Disclosure - Organization - Additional Information (Detail) link:presentationLink link:calculationLink link:definitionLink 100370 - Disclosure - Financings - Additional Information (Detail) link:presentationLink link:calculationLink link:definitionLink 100380 - Disclosure - Summary of Significant Accounting Policies - Additional Information (Detail) link:presentationLink link:calculationLink link:definitionLink 100390 - Disclosure - Summary of Significant Accounting Policies - Assets and Liabilities Measured at Fair Value on Recurring Basis (Detail) link:presentationLink link:calculationLink link:definitionLink 100400 - Disclosure - Summary of Significant Accounting Policies - Impact of Topic 606 Adoption on Financial Statements (Detail) link:presentationLink link:calculationLink link:definitionLink 100410 - Disclosure - Summary of Significant Accounting Policies - Stock-Based Compensation Expense Included in Statement of Operations (Detail) link:presentationLink link:calculationLink link:definitionLink 100420 - Disclosure - Summary of Significant Accounting Policies - Fair Value of Stock Options Assumptions Using Black-Scholes Option Valuation Model (Detail) link:presentationLink link:calculationLink link:definitionLink 100430 - Disclosure - Summary of Significant Accounting Policies - Earning Per share Basic and Diluted (Detail) link:presentationLink link:calculationLink link:definitionLink 100440 - Disclosure - Summary of Significant Accounting Policies - Potential Dilutive Shares Excluded from Computation of Diluted Net Loss Per Share (Detail) link:presentationLink link:calculationLink link:definitionLink 100450 - Disclosure - Debt - Schedule of Debt (Details) link:presentationLink link:calculationLink link:definitionLink 100460 - Disclosure - Debt - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 100470 - Disclosure - Property and Equipment, net - Component of Property and Equipment, Net (Detail) link:presentationLink link:calculationLink link:definitionLink 100480 - Disclosure - Property and Equipment, net - Additional Information (Detail) link:presentationLink link:calculationLink link:definitionLink 100490 - Disclosure - Accrued Expenses - Component of Accrued Expenses (Detail) link:presentationLink link:calculationLink link:definitionLink 100500 - Disclosure - Related Party Transactions - Additional Information (Detail) link:presentationLink link:calculationLink link:definitionLink 100510 - Disclosure - Leases - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 100520 - Disclosure - Leases - Components of Lease Expense (Details) link:presentationLink link:calculationLink link:definitionLink 100530 - Disclosure - Leases - Operating Lease Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 100540 - Disclosure - Commitments and Contingencies - Additional Information (Detail) link:presentationLink link:calculationLink link:definitionLink 100550 - Disclosure - Warrants - Additional Information (Detail) link:presentationLink link:calculationLink link:definitionLink 100560 - Disclosure - Restructuring - Additional Information (Detail) link:presentationLink link:calculationLink link:definitionLink 100570 - Disclosure - Restructuring - Future termination benefit payments resulting from the strategic reduction in force (Detail) link:presentationLink link:calculationLink link:definitionLink 100580 - Disclosure - Income Taxes - Significant Component of Deferred Tax Assets (Detail) link:presentationLink link:calculationLink link:definitionLink 100590 - Disclosure - Income Taxes - Reconciliation of Income Tax Expense (Benefit) (Detail) link:presentationLink link:calculationLink link:definitionLink 100600 - Disclosure - Income Taxes - Additional Information (Detail) link:presentationLink link:calculationLink link:definitionLink 100610 - Disclosure - Preferred Stock and Stockholders' Equity (Deficit) - Additional Information (Detail) link:presentationLink link:calculationLink link:definitionLink 100620 - Disclosure - Derivative Financial Instruments - Change in Derivative Liability (Detail) link:presentationLink link:calculationLink link:definitionLink 100630 - Disclosure - Derivative Financial Instruments - Fair Value Assumptions Used in Probability Weighted Approach and Monte Carlo Simulation Model for Derivatives (Detail) link:presentationLink link:calculationLink link:definitionLink 100640 - Disclosure - Stock Option Plan - Additional information (Detail) link:presentationLink link:calculationLink link:definitionLink 100650 - Disclosure - Stock Option Plan - Stock Option Activity Under Stock Option Plan (Detail) link:presentationLink link:calculationLink link:definitionLink 100660 - Disclosure - Stock Option Plan - Summary of Non-Vested Restricted Stock (Detail) link:presentationLink link:calculationLink link:definitionLink 100670 - Disclosure - Employee Benefit Plan - Additional Information (Detail) link:presentationLink link:calculationLink link:definitionLink 100680 - Disclosure - Joint Venture - Additional Information (Detail) link:presentationLink link:calculationLink link:definitionLink