100000 - Document - Cover Page
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100010 - Statement - BALANCE SHEETS
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100020 - Disclosure - Debt - Schedule of Debt (Details) 2
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100030 - Disclosure - Leases - Operating Lease Liabilities (Details) 2
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100040 - Statement - BALANCE SHEETS (Parenthetical)
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100050 - Statement - STATEMENTS OF OPERATIONS
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100060 - Statement - STATEMENTS OF CHANGES IN STOCKHOLDERS' EQUITY
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100070 - Statement - STATEMENTS OF CASH FLOWS
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995455 - Disclosure - Organization
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995465 - Disclosure - Financings
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995475 - Disclosure - Summary of Significant Accounting Policies
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995485 - Disclosure - Debt
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995495 - Disclosure - Property and Equipment, net
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995505 - Disclosure - Accrued Expenses
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995515 - Disclosure - Related Party Transactions
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995525 - Disclosure - Leases
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995535 - Disclosure - Commitments and Contingencies
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995545 - Disclosure - Warrants
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995555 - Disclosure - Restructuring
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995565 - Disclosure - Income Taxes
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995575 - Disclosure - Stock Option Plan
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995585 - Disclosure - Employee Benefit Plan
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995595 - Disclosure - Joint Venture
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995605 - Disclosure - Subsequent Events
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995615 - Disclosure - Summary of Significant Accounting Policies (Policies)
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995625 - Disclosure - Summary of Significant Accounting Policies (Tables)
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995635 - Disclosure - Debt (Tables)
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995645 - Disclosure - Property and Equipment, net (Tables)
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995655 - Disclosure - Accrued Expenses (Tables)
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995665 - Disclosure - Leases (Tables)
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995675 - Disclosure - Income Taxes (Tables)
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995685 - Disclosure - Stock Option Plans (Tables)
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995695 - Disclosure - Organization - Additional Information (Detail)
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995705 - Disclosure - Financings - Additional Information (Detail)
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995715 - Disclosure - Summary of Significant Accounting Policies - Additional Information (Detail)
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995725 - Disclosure - Summary of Significant Accounting Policies - Assets and Liabilities Measured at Fair Value on Recurring Basis (Detail)
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995735 - Disclosure - Summary of Significant Accounting Policies - Stock-Based Compensation Expense Included in Statement of Operations (Detail)
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995745 - Disclosure - Summary of Significant Accounting Policies - Fair Value of Stock Options Assumptions Using Black-Scholes Option Valuation Model (Detail)
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995755 - Disclosure - Summary of Significant Accounting Policies - Earning Per share Basic and Diluted (Detail)
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995765 - Disclosure - Summary of Significant Accounting Policies - Potential Dilutive Shares Excluded from Computation of Diluted Net Loss Per Share (Detail)
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995775 - Disclosure - Debt - Schedule of Debt (Details)
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995785 - Disclosure - Debt - Additional Information (Details)
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995795 - Disclosure - Property and Equipment, net - Component of Property and Equipment, Net (Detail)
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995805 - Disclosure - Property and Equipment, net - Additional Information (Detail)
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995815 - Disclosure - Accrued Expenses - Component of Accrued Expenses (Details)
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995825 - Disclosure - Related Party Transactions - Additional Information (Details)
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995835 - Disclosure - Leases - Additional Information (Details)
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995845 - Disclosure - Leases - Components of Lease Expense (Details)
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995855 - Disclosure - Leases - Operating Lease Liabilities (Details)
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995865 - Disclosure - Commitments and Contingencies - Additional Information (Detail)
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995875 - Disclosure - Warrants - Additional Information (Details)
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995885 - Disclosure - Restructuring - Additional Information (Details)
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995895 - Disclosure - Income Taxes - Significant Component of Deferred Tax Assets (Detail)
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995905 - Disclosure - Income Taxes - Additional Information (Detail)
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995915 - Disclosure - Income Taxes - Reconciliation of Income Tax Expense (Benefit) (Detail)
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995925 - Disclosure - Preferred Stock and Stockholders' Equity (Deficit) - Additional Information (Detail)
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995935 - Disclosure - Stock Option Plan - Additional information (Detail)
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995945 - Disclosure - Stock Option Plan - Stock Option Activity Under Stock Option Plan (Detail)
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995955 - Disclosure - Stock Option Plan - Summary of Non-Vested Restricted Stock (Detail)
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995965 - Disclosure - Employee Benefit Plan - Additional Information (Detail)
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995975 - Disclosure - Joint Venture - Additional Information (Details)
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995985 - Disclosure - Subsequent Events - Additional Information (Details)
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Additional loans committed.
Additional Loans Committed
Additional Loans Committed
Federal and State [Member]
Federal and State [Member]
Federal and State
Income Taxes [Table]
Income Taxes [Table]
Income Taxes [Table]
Auditor Firm ID
Clinical expenses
Clinical Expenses
Clinical expenses.
2024
Lessee, Operating Lease, Liability, to be Paid, Year One
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Arrangements and Non-arrangement Transactions [Domain]
Document Transition Report
Expected volatility
Expected volatility
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term
Outstanding, at end of period
MD Anderson Related to the 2015 R&D Agreement [Member]
M D Anderson License and the Two Thousand Fifteen Research and Development Agreement [Member]
M D Anderson license and the two thousand fifteen research and development agreement.
Milestone payment.
Milestone Payment
One time milestone payment
Annual License Fees
Annual License Fees
Annual License fee
Geographical [Axis]
Geographical [Axis]
Vest in period.
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period
Other Liabilities, Noncurrent
Other non-current liabilities
Increase (Decrease) in Prepaid Expense and Other Assets, Total
Increase (Decrease) in Prepaid Expense and Other Assets
Prepaid expenses and other current assets
Restricted Stock Units (RSUs) [Member]
Deferred tax assets capitalized acquisition costs.
Deferred Tax Assets, Capitalized Acquisition Costs
Capitalized acquisition costs
Fair Value, Inputs, Level 1 [Member]
Quoted Prices in Active Markets for Identical Assets/Liabilities (Level 1) [Member]
Entity Public Float
2027
Lessee, Operating Lease, Liability, to be Paid, Year Four
Temporary Equity, Shares Authorized
Preferred stock, shares authorized
Income Tax, Policy [Policy Text Block]
Income Taxes
Property, Plant and Equipment, Useful Life
Property and equipment useful life
Revenue from Contract with Customer, Excluding Assessed Tax, Total
Revenue from Contract with Customer, Excluding Assessed Tax
Collaboration revenue
Revenue
Disclosure of accounting policy for warrants.
Warrants [Policy Text Block]
Warrants
At The Market Offering [Member]
At The Market Offering Member
Market Offering [Member]
At The Market Offering [Member]
Licensed Products Member
Licensed Products [Member]
Other income expense member.
Other Income Expense [Member]
Other Income Expense [Member]
Share-based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount, Total
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount
Unrecognized stock-based compensation expense related to non-vested restricted stock arrangements
Valuation Allowance, Deferred Tax Asset, Increase (Decrease), Amount
Increase (decrease) in deferred tax assets
Annual Grant [Member]
Annual Grant [Member]
Annual grant
Conditional milestone amount payable.
Conditional Milestone Amount Payable
Conditional milestone amount payable
Equity Method Investments and Joint Ventures [Abstract]
ICFR Auditor Attestation Flag
NumberofDaysOptionExerciable
Number of Days Option Exerciable
Maximum royalty amount
Maximum Amount of Royalty Payable
Maximum amount of royalty payable.
Gain on lease modification and termination
Gain on lease termination
Gain (Loss) on Termination of Lease
Silicon Valley Bank [Member]
Silicon Valley Bank [Member]
Silicon valley bank.
Represents Description Of Option To Terminate The Agreement Upon Not Meeting Certain Milestones.
Description Of Option To Terminate The Agreement Upon Not Meeting Certain Milestones
Description Of option To terminate Agreement
Title of Individual [Domain]
Relationship to Entity [Domain]
Tcell Receptor Member
T-Cell Receptor [Member]
T-Cell Receptor [Member]
Subsequent Events
Subsequent Events [Text Block]
Performance based payments.
Performance Based Payments [Member]
Milestone payment made One.
Milestone Payment Made One
Milestone payment made
Stock Issued During Period, Shares, Issued for Services
Issuance of common stock in licensing agreement (in shares)
Temporary Equity, Shares Issued
Preferred stock, shares issued
Share-based Compensation Arrangement by Share-based Payment Award, Options, Aggregate Intrinsic Value [Abstract]
Share-based Compensation Arrangement by Share-based Payment Award, Options, Aggregate Intrinsic Value [Abstract]
Aggregate Intrinsic Value
Portion of income payable to related party
Percentage of Sub licensing Income Payable to Related Party
Percentage of sub licensing income, attributable to related party.
Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block]
Assets and Liabilities Measured at Fair Value on Recurring Basis
Common Stock, Shares Subscribed but Unissued
Common stock
Stock Repurchased During Period, Shares
Repurchase of shares of restricted common stock
Repurchase of common stock (in shares)
Repurchase of Shares of Restricted Stock
Schedule of Stock by Class [Table]
Issuance of Common Stock to Underwriters
Aggregate Amount Potentially Reimburseable Amount.
Aggregate Amount Potentially Reimburseable Amount
Reimbursement of historical costs
Underwriting Agreement
Underwriting Agreement [Member]
Underwriting Agreement [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number of Shares [Roll Forward]
Number of Shares
Lease liabilities, non-current
Finance Lease, Liability, Noncurrent
Unamortized discount on Loan and Security Agreement
Unamortized discount on Loan and Security Agreement
Debt Instrument, Unamortized Discount
Debt Instrument, Unamortized Discount, Total
Employee Severance [Member]
Employee Severance [Member]
Payments to Fund Long-Term Loans to Related Parties
Payments to Fund Long-term Loans to Related Parties
Operating Loss Carryforwards Research Expiration Dates
Operating Loss Carryforwards Research Expiration Dates
Net operating loss carryforwards, expiration date
Related Party Transactions [Abstract]
Balance Sheet Location [Axis]
Balance Sheet Location [Axis]
Assets, Current
Total current assets
Expected additional milestones payable
Maximum Amount of Additional Milestones Payable
Maximum amount of additional milestones payable.
Vesting [Domain]
Liabilities and Equity
Total liabilities and stockholders' equity
Entity Address, State or Province
Deferred Tax Assets, Other
Other
Sublease Area
Sublease Area
Sublease area.
Stock Issued During Period, Value, New Issues
Issuance of common stock, net of expenses
Aggregate offering price
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number
Ending Balance
Beginning Balance
Outstanding options issued
Represents Potential Benchmark Payments Payable.
Potential Benchmark Payments Payable
Potential Benchmark Payments Payable
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value
Weighted average fair value of stock option granted
DeferredTaxAssetsLeaseLiability.
Deferred Tax Assets Lease Liability
Lease liability
Trading Symbol
Deferred Tax Assets, Net of Valuation Allowance
Total deferred tax assets
Debt Instrument, Redemption, Period [Axis]
Common Stock, Shares, Issued, Total
Common Stock, Shares, Issued
Common stock, shares issued
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Share-Based Payment Arrangement, Percent
Stock-based compensation
Operating Costs and Expenses [Abstract]
Operating expenses:
Agreement Type Axis Axis
Agreement Type Axis [Axis]
Dividends [Axis]
Dividends [Axis]
Prepaid Expense and Other Assets, Current
Prepaid expenses and other current assets
MA
MA [Member]
Boston, MA [Member]
Compensation and Employee Benefit Plans [Text Block]
Employee Benefit Plan
Consolidated Entities [Domain]
Mr. Hogue
Hogue [Member]
Hogue Member.
Schedule of Long-Term Debt Instruments [Table]
Shares, Outstanding
Balance (in shares)
Balance (in shares)
Lab Equipment [Member]
Lab Equipment [Member]
Lab equipment.
2026
Lessee, Operating Lease, Liability, to be Paid, Year Three
Common Stock, Capital Shares Reserved for Future Issuance
Common stock reserved for future issuance
Common Stock, shares reserved for future issuance
Subsidiary or Equity Method Investee [Line Items]
Less: long-term debt, current
Current portion of long-term debt
Long-Term Debt, Current Maturities
Long-term Debt, Current Maturities, Total
Entity Address, City or Town
Related Party Transaction [Line Items]
Related Party Transaction [Line Items]
Operating Lease, Weighted Average Discount Rate, Percent
Weighted-average discount rate
Debt
Debt Disclosure [Text Block]
Property, Plant and Equipment [Table Text Block]
Component of Property and Equipment, Net
Deferred Tax Assets, Operating Loss Carryforwards, Subject to Expiration
Deferred tax assets operating loss carryforwards with expire date
Subsequent Event [Member]
Subsequent Event Type [Axis]
Subsequent Event Type [Axis]
Term B Tranche [Member]
Share-Based Payment Arrangement, Tranche Two [Member]
Property and equipment estimated useful life, Description [Extensible Enumeration]
Property, Plant, and Equipment, Useful Life, Term, Description [Extensible Enumeration]
Gain (loss) on modification of lease.
Gain (Loss) On Modification Of Lease
Gain (Loss) On Modification Of Lease
Liabilities, Current [Abstract]
Current liabilities:
Assets, Current [Abstract]
Current assets:
Preferred Stock, Par or Stated Value Per Share
Preferred stock, par value
Statement of Stockholders' Equity [Abstract]
Recognition in exchange of Operating Lease Liabilities
Operating Lease, Liability, Current
Description of payment terms
Line of Credit Facility, Frequency of Payment and Payment Terms
Contribution payable on per annum basis.
Contribution Payable on Per Annum Basis
Contribution payable on per annum basis
Pre stock split shares authorized
Pre Stock Split Shares Authorized
Pre Stock Split Shares Authorized
Property, Plant and Equipment, Net, Ending Balance
Property, Plant and Equipment, Net, Beginning Balance
Property, Plant and Equipment, Net
Property and equipment, net
Property and equipment, net
Class of Stock [Domain]
Class of Stock [Domain]
Restructuring costs
Restructuring Charges
Restructuring Charges, Total
Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent
Federal income tax at statutory rates
Deferred tax assets depreciation.
Deferred Tax Assets, Depreciation
Depreciation
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Type of Arrangement and Non-arrangement Transactions [Axis]
Entity Central Index Key
Tenth Scheduled Payment
Tenth Scheduled Payment [Member]
Tenth Scheduled Payment.
Lease liabilities, current
Finance Lease, Liability, Current
Class of Warrant or Right, Number of Securities Called by Warrants or Rights
Number of Warrants
Number of securities into which the class of warrant converted
Plan Name [Domain]
Plan Name [Domain]
Includes disclosures related to financing receivables and financing guarantees in which the company is the guarantor.
Financing Arrangements Disclosure [Text Block]
Financings
Lessee, Operating Lease, Option to Extend
Lease term, description
Liabilities, Current
Total current liabilities
Entity Tax Identification Number
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table]
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table]
Increase (Decrease) in Operating Capital [Abstract]
Change in operating assets and liabilities:
Deposits Assets, Noncurrent
Deposits
Financial Instruments [Domain]
Line of Credit Facility [Table]
Investment, Name [Axis]
Share-Based Payment Arrangement, Expense, after Tax
Net share based employee compensation expense
Construction in Progress [Member]
Construction-in-process
Annual cash retainer received
Annual Cash Retainer
Annual cash retainer.
Lessee, Operating Leases [Text Block]
Leases
Payments due prior to the first marketing approval for TCR products.
Accruals Prior to First Marketing Approval
Payments due prior to the first marketing approval
Patent And Technology License Agreement [Member]
Patent And Technology License Agreement [Member]
Patent and technology license agreement.
Restricted Stock [Member]
Restricted Stock [Member]
Unvested Restricted Stock [Member]
Plan Name [Axis]
Plan Name [Axis]
Eden Biocell.
Eden Biocell [Member]
Geographical [Domain]
Geographical [Domain]
Assets
Total assets
Right-of-use assets
Operating Lease, Right-of-Use Asset
Line of Credit Facility [Line Items]
Entity Registrant Name
Issuance costs
Debt Issuance Costs, Net
Debt Issuance Costs, Net, Total
Underwriting Agreement With Jefferies Member
Underwriting Agreement with Jefferies [Member]
Underwriting Agreement with Jefferies [Member]
Related Party, Type [Domain]
Related Party [Domain]
Retained Earnings (Accumulated Deficit), Ending Balance
Retained Earnings (Accumulated Deficit), Beginning Balance
Retained Earnings (Accumulated Deficit), Total
Retained Earnings (Accumulated Deficit)
Accumulated deficit
Supplemental Cash Flow Information [Abstract]
Supplementary disclosure of cash flow information:
Retained Earnings [Member]
Accumulated Deficit [Member]
Class of Stock [Axis]
Class of Stock [Axis]
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number
Ending Balance
Beginning Balance
Consulting Agreement Provides for Compensation
Deferred Compensation Arrangement with Individual, Compensation Expense
Minimum
Minimum [Member]
Minimum [Member]
Represents Description Of First Benchmark Payable.
Description Of First Benchmark Payable
Description Of First Benchmark Payable
Proceeds from the exercise of stock options
Proceeds from Stock Options Exercised
Proceeds from stock options exercised
Significant Accounting Policies [Text Block]
Summary of Significant Accounting Policies
Operating Lease, Liability, Total
Operating Lease, Liability
Present value of lease payments
Termination benefits
Severance Costs
Severance costs
Term A Tranche [Member]
Share-Based Payment Arrangement, Tranche One [Member]
Revenue [Policy Text Block]
Revenue Recognition from Collaboration Agreements
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Minimum
Expected volatility, Minimum
Equity Component [Domain]
Equity Component [Domain]
Two thousand twenty equity incentive plan.
Two Thousand Twenty Equity Incentive Plan [Member]
the "2020 Plan" [Member]
Defined Benefit Plan, Plan Assets, Contributions by Employer
Defined benefit plan contributions by employer
Software Development [Member]
Software [Member]
Share Subscription Agreement
Share Subscription Agreement [Member]
Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract]
Adjustments to reconcile net loss to net cash used in operating activities:
Measurement Frequency [Axis]
Measurement Frequency [Axis]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract]
Weighted Average Exercise Price
Debt Disclosure [Abstract]
Non Vested Stock [Member]
Non Vested Stock [Member]
Unvested Stock [Member]
Line of credit facility, interest rate
Debt Instrument, Basis Spread on Variable Rate
Operating Lease, Liability, Statement of Financial Position [Extensible Enumeration]
Operating lease liability statement of financial position [extensible list]
Entity Current Reporting Status
Common Stock, Shares Authorized
Common stock, shares authorized
Research and Development Expense, Total
Research and Development Expense
Research and development
Research and development expense
Assets [Abstract]
ASSETS
Schedule of Earnings Per Share, Diluted, by Common Class, Including Two Class Method [Table Text Block]
Schedule of Earnings Per Share, Diluted, by Common Class, Including Two Class Method
Proceeds from Issuance of Common Stock
Proceeds from the issuance of common stock
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant
Options available for future grant
Effective income tax rate reconciliation nondeductible expense federal rate change.
Effective Income Tax Rate Reconciliation Nondeductible Expense Federal Rate Change
Federal/state rate change
Common stock $0.001 par value; 34,666,667 shares authorized, 16,012,522 shares issued and outstanding at December 31, 2023 and 28,000,000 shares authorized,16,027,384 shares issued and outstanding at December 31, 2022
Common Stock, Value, Issued, Ending Balance
Common Stock, Value, Issued, Beginning Balance
Common Stock, Value, Issued, Total
Common Stock, Value, Issued
Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Percent
Change in valuation allowance
Repayments of Long-Term Debt, Total
Repayments of Long-Term Debt
Repayment of long-term debt
Payment Type Axis
Payment Type [Axis]
Proceeds from the disposal of property and equipment
Proceeds from Sale of Property, Plant, and Equipment, Total
Proceeds from Sale of Property, Plant, and Equipment
Accrued Liabilities, Current
Accrued expenses
Total
Current Fiscal Year End Date
Share-based Payment Arrangement, Noncash Expense, Total
Share-Based Payment Arrangement, Noncash Expense
Stock based compensation expenses
Stock-based compensation expense
Payment Type Domain
Payment Type [Domain]
Auditor Name
Unrecognized Tax Benefits, Period Increase (Decrease), Total
Unrecognized Tax Benefits, Period Increase (Decrease)
Uncertain Tax Positions Adjustment
Operating Income (Loss)
Loss from operations
Loss from operations
Intrexon Corporation Member
Intrexon Corporation/Precigen [Member]
Intrexon Corporation/Precigen
Intrexon Corporation [Member]
Research and Development Expense [Member]
Research and Development [Member]
Eligibility of bonus percentage.
Eligibility Of Bonus Percentage
Eligible bonus percentage
Royalty [Member]
Accounts Payable and Accrued Liabilities Disclosure [Text Block]
Accrued Expenses
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Maximum
Expected volatility, Maximum
Fair Value Assumptions Expected volatility Rate Maximum
Securities Purchase Agreement [Member]
Securities Purchase Agreement.
Securities Purchase Agreement [Member]
Initial Grant [Member]
Initial Grant [Member]
Initial grant
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Net of Forfeitures, Total
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Net of Forfeitures
Granted
Stock options, granted
Leases, Operating [Abstract]
Impairment or Disposal of Long-Lived Assets, Policy [Policy Text Block]
Long-Lived Assets
Stock Issued During Period, Shares, Restricted Stock Award, Gross
Restricted stock awards (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value
Outstanding, at end of period
Loan and Security Agreement
Debt Instrument, Face Amount
Earnings Per Share, Policy [Policy Text Block]
Net Loss per Share
Other income , net
Other Nonoperating Income (Expense), Total
Other Nonoperating Income (Expense)
Common stock options.
Common stock options [Member]
Common stock options [Member]
Property, Plant and Equipment [Abstract]
Banking and Thrift, Interest [Abstract]
Entity Voluntary Filers
Subsequent Events [Abstract]
SVB Warrants [Member]
Svb Warrants [Member]
Svb Warrants [Member].
Svb Warrants [Member]
Effective income tax rate limitation on adjusted taxable income.
Effective Income Tax Rate Limitation On Adjusted Taxable Income
Relaxation of Adjusted taxable income, percentage
Due Date Domain
Due date [Domain]
Eight Scheduled Payment
Eighth Scheduled Payment [Member]
Eighth Scheduled Payment.
Commitments and Contingencies Disclosure [Abstract]
Other Assets, Noncurrent, Total
Other Assets, Noncurrent
Other non-current assets
Common stock shares awarded
Stock option granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross
Other
Other Accrued Liabilities, Current
Depreciation, Total
Depreciation
Depreciation
Cash paid for interest
Interest Paid, Excluding Capitalized Interest, Operating Activities
Deferred Tax Assets, Operating Loss Carryforwards, Not Subject to Expiration
Deferred tax assets operating loss carryforwards without expire date
Office and Computer Equipment [Member].
Office And Computer Equipment [Member]
Office and computer equipment [Member]
Equity, Attributable to Parent [Abstract]
Stockholders' equity:
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Lessee, Operating Lease, Liability, to be Paid, after Year Five
Thereafter
Lease, Cost [Table Text Block]
Components of Lease Expense
Entity [Domain]
Entity [Domain]
Loss on sale of equipment, net
Gain on disposal of equipment
Gain (Loss) on Disposition of Property Plant Equipment, Total
Gain (Loss) on Disposition of Property Plant Equipment
Additonal tranche facility
Line of Credit Facility, Maximum Borrowing Capacity
Termination costs
Termination Costs
Termination costs
Earnings Per Share [Abstract]
Maximum amount of royalty.
Maximum Royalty Amount
Maximum royalty amount
Lessee, Operating Lease, Liability, to be Paid, Maturity [Table Text Block]
Lessee, Operating Lease, Liability, Maturity
Investment, Name [Domain]
Debt instrument, initial maturity date
Debt Instrument, Maturity Date Range, Start
Deferred Tax Liabilities, Net, Total
Deferred Tax Liabilities, Net
Total deferred tax liabilities
Accounting Policies [Abstract]
Concentration Risk, Credit Risk, Policy [Policy Text Block]
Concentrations of Credit Risk
Issuance of common stock in connection with a public offering, net
Sale of Stock, Consideration Received on Transaction
Sale of stock consideration received on transaction
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Stock Option [Member]
Equity Option [Member]
MD Anderson Agreement and Worldwide License [Member]
MD Anderson Agreement and Worldwide License.
MD Anderson Agreement and Worldwide License [Member]
Net income (loss) per share, basic
Net loss per share, basic
Earnings per share, Basic
Net loss per share, basic
Commitments and Contingencies
Commitments and contingencies (Note 9)
Income Statement [Abstract]
Property, Plant and Equipment Disclosure [Text Block]
Property and Equipment, net
Related Party, Type [Axis]
Related Party [Axis]
Warrants Disclosure Abstract
Warrants Disclosure [Abstract]
Accounting Standards Update and Change in Accounting Principle [Table Text Block]
Impact of Topic 606 Adoption on Financial Statements
Operating Lease, Cost
Operating lease cost
Leases other than short-term lease
Short-Term Lease, Cost
Earning Per share Basic and Diluted
Earning Per share Basic and Diluted [Table]
Retirement Benefits [Abstract]
Fixed asset impairment charges
Tangible Asset Impairment Charges
Tangible Asset Impairment Charges, Total
Restructuring Type [Axis]
Statistical Measurement [Domain]
Range [Domain]
Net Cash Provided by (Used in) Operating Activities
Net cash used in operating activities
Accrued preclinical services current.
Accrued Preclinical Services Current
Preclinical services
Notice period
Advance Notice Period for Termination Agreement
Advance notice period for termination agreement.
Series 1 Preferred Stock [Member]
Series 1 Preferred Stock [Member]
Series 1 Preferred Stock
Document Period End Date
The maximum number of shares permitted to be issued by an entity's charter and bylaws.
Shares Authorized
Shares of authorized capital stock
Statistical Measurement [Axis]
Range [Axis]
Commitments and Contingencies Disclosure [Text Block]
Commitments and Contingencies
Operating Lease, Payments
Operating Lease, Payments
Lease income
Lease Income
Lease Income, Total
Second anniversary
Debt Instrument, Redemption, Period Two [Member]
Net income (loss) per share, diluted
Net loss per share, diluted
Earnings per share, Diluted
Net loss per share, diluted
Product and Service [Domain]
Tri Arm
Tri Arm [Member]
Non Operating Income Expense Inducement Of Warrants.
Non Operating Income Expense Inducement Of Warrants
Non-cash inducement warrant expense
Non-cash inducement warrant expense
Non-cash inducement warrant expense
Deferred Tax Assets, Operating Loss Carryforwards, Total
Deferred Tax Assets, Operating Loss Carryforwards
Net operating loss carryforwards
Debt Instrument, Name [Domain]
Stock Options and Restricted Stock Awards.
Stock Options And Restricted Stock Awards Text Block [Text Block]
Stock Option Plan
Fair Value Hierarchy and NAV [Domain]
Fair Value Hierarchy [Domain]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number
Options exercisable, at end of period
Increase (Decrease) in Other Noncurrent Liabilities
Other non-current liabilities
One Time Benchmark Payments Member
One Time Benchmark Payments [Member]
Fair Value, Recurring [Member]
Fair Value, Measurements, Recurring [Member]
Additional Paid in Capital, Common Stock, Ending Balance
Additional Paid in Capital, Common Stock, Beginning Balance
Additional Paid in Capital, Common Stock
Additional paid-in capital
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding [Roll Forward]
Number of Shares
Deferred Tax Assets, Net
Net deferred taxes
Organizational Changes
Organizational Changes [Policy Text Block]
Disclosure of accounting policy for organizational changes.
Agreement termination date
Agreement Termination Date
Termination Date of CRADA Agreement
Payments for Repurchase of Common Stock
Repurchase of common stock
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period
Exercise of employee stock options (in shares)
Exercised
Dune Lake Capital
Dune Lake Capital [Member]
Dune Lake Capital
Liabilities and Equity [Abstract]
LIABILITIES, PREFERRED STOCK AND STOCKHOLDERS' EQUITY
Income Taxes [Line Items]
Income Taxes [Line Items]
Income Taxes [Line Items]
Share-based Compensation Arrangement by Share-based Payment Award, Options, Weighted Average Remaining Contractual Term [Abstract]
Share-based Compensation Arrangement by Share-based Payment Award, Options, Weighted Average Remaining Contractual Term [Abstract]
Weighted Average Contractual Term (Years)
Warrants issued
Debt Conversion, Converted Instrument, Warrants or Options Issued
Entity Address, Postal Zip Code
Obligations due under contract.
Obligations Due Under Contract
Obligations due under contract
Entity Interactive Data Current
Private Placement [Member]
MD Anderson [Member]
MD Anderson [Member]
MD Anderson [Member]
Increase (Decrease) in Accounts Payable, Total
Increase (Decrease) in Accounts Payable
Accounts payable
Credit Facility [Domain]
Credit Facility [Domain]
Text Block [Abstract]
Less: imputed interest
Lessee, Operating Lease, Liability, Undiscounted Excess Amount
Percentage Of Commission On Gross Proceeds From Sale Of Common Stock
Percentage Of Commission On Gross Proceeds From Sale Of Common Stock
Percentage of commission on gross proceeds from sale of common stock
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period
Granted
Share-based payment award granted
Entity Well-known Seasoned Issuer
Revision of Prior Period [Axis]
Strategic advisor name
Strategic Advisor Name
Strategic advisor name.
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
Exercised
Entity Incorporation, State or Country Code
Cash and Cash Equivalents, Policy [Policy Text Block]
Cash and Cash Equivalents
Equity Components [Axis]
Equity Components [Axis]
Milestone payments maximum amount.
Milestone Payments, Maximum Amount
Milestone maximum payment
Restructuring and Related Activities [Abstract]
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value
Vested
Local Phone Number
Property, Plant and Equipment [Line Items]
Property, Plant and Equipment [Line Items]
Sale of Stock [Axis]
At The Market Offering [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price
Options exercisable, at end of period
Research Tax Credit Carryforward [Member]
Research Tax Credit Carryforward
Stock issued during period
Stock Offered During Period Shares
Stock offered during period shares.
Restricted Cash, Current
Restricted cash
Statement of Cash Flows [Abstract]
Non-Employee Director [Member]
Director [Member]
Employee stock option and Restricted stock.
Employee Stock Option And Restricted Stock Member
Stock Options and Restricted Stock [Member]
Income Tax Authority [Domain]
Income Tax Authority [Domain]
Property, Plant and Equipment, Policy [Policy Text Block]
Property and Equipment
Document Annual Report
Common stock, par value
Common Stock, Par or Stated Value Per Share
Initial Public Offering of Common Stock
Class Of Warrant Or Right Axis.
Class Of Warrant Or Right Axis [Axis]
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Expected recognition period
Long-Lived Tangible Asset [Axis]
Property, Plant and Equipment, Type [Axis]
Common stock awarded
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Authorized
Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]
Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table]
Maximum
Maximum [Member]
Maximum [Member]
ZiopLicenseAgreementWithTheNationalCancerInstituteMember
Ziop License Agreement With The National Cancer Institute [Member]
Ziop License Agreement With The National Cancer Institute [Member]
Proceeds from Issuance of Private Placement
Proceeds from private placement
Proceeds from private placement
The University Of Texas M D Anderson Cancer Center And The Texas A And M University System
The University Of Texas M D Anderson Cancer Center And The Texas A And M University System [Member]
The University of Texas MD Anderson Cancer Center and The Texas A & M University System [Member]
Temporary Equity, Shares Outstanding
Preferred stock, shares outstanding
Dividends
Dividends
Dividends, Total
Payment under license agreement
Payment Under License Agreement
Payment under license agreement.
Threshold period for exercise or conversion of stock
Threshold Commitment Period for Exercise of Rights to Participate in Future Offerings
Threshold commitment period for exercise of rights to participate in future offerings.
APIC, Share-based Payment Arrangement, Increase for Cost Recognition, Total
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition
Stock-based compensation
Fair Value, Recurring and Nonrecurring [Table]
Fair Value Measurements, Recurring and Nonrecurring [Table]
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect
Net decrease in cash, cash equivalents and restricted cash
Payables and Accruals [Abstract]
General and Administrative Expense [Member]
General and Administrative [Member]
Increase decrease in operating deposits.
Increase Decrease in Operating Deposits
Deposits
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period
Cancelled
Document Financial Statement Error Correction [Flag]
Stock Issued During Period, Shares, Restricted Stock Award, Forfeited
Cancelled restricted common stock (in shares)
Effective income tax rate reconciliation nondeductible expense research and development true up.
Effective Income Tax Rate Reconciliation Nondeductible Expense Research and Development True Up
Research and development true-up
Value received from shareholders in common stock-related transactions that are in excess of par value or stated value and amounts received from other stock-related transactions. Includes only common stock transactions (excludes preferred stock transactions). May be called contributed capital, capital in excess of par, capital surplus, or paid-in capital.
Additional Paid in Capital, Common Stock [Member]
Additional Paid In Capital [Member]
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Potentially Dilutive Shares Excluded from Computation of Diluted Net Loss Per Share
City Area Code
Research and Development Arrangement, Contract to Perform for Others, Type [Axis]
Postemployment Benefits [Abstract]
Net Cash Provided by (Used in) Operating Activities [Abstract]
Cash flows from operating activities:
Amount of prepayments premium
Amount Of Prepayments Premium
Amount Of Prepayments Premium.
Aggregate potential benchmark payments.
Aggregate potential benchmark payments
Aggregate potential benchmark payments
MD Anderson License and the Research and Development Agreement [Member]
MD Anderson License and the Research and Development Agreement.
MD Anderson License and the Research and Development Agreement [Member]
Property And Equipment And Right Of Use Assets Impairment
Property and equipment and right of use assets impairment
Property and equipment and right-of-use assets impairment
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Ending Balance
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Beginning Balance
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Total
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment
Less: accumulated depreciation
General and Administrative Expense, Total
General and Administrative Expense
General and administrative
Temporary Equity, Liquidation Preference
Preferred stock, liquidation preference
Weighted average common shares outstanding, basic
Weighted Average Number of Shares Outstanding, Basic, Total
Weighted Average Number of Shares Outstanding, Basic
Weighted average common shares outstanding used to compute basic net income (loss) per share
Equity Distribution Agreement [Member]
Equity Distribution Agreement [Member]
Equity distribution agreement.
Research and Development Arrangement, Contract to Perform for Others, Type [Domain]
Net Cash Provided by (Used in) Financing Activities [Abstract]
Cash flows from financing activities:
Research and Development Expense, Policy [Policy Text Block]
Research and Development Costs
Schedule Of Equity [Table]
Schedule Of Equity [Table]
Schedule Of Equity [Table]
Statement [Table]
Statement [Table]
Stock Option Activity Under Stock Option Plan
Share-Based Payment Arrangement, Option, Activity [Table Text Block]
Schedule of Related Party Transactions, by Related Party [Table]
Schedule of Related Party Transactions, by Related Party [Table]
Represents Minimum Royalties Amount Payable.
Minimum Royalties Amount Payable
Minimum royalties amount payable
Document Fiscal Period Focus
Lessee, Operating Lease, Liability, to be Paid
Total lease payments
Summary Of Significant Accounting Policies [Table]
Summary Of Significant Accounting Policies [Table]
Summary Of Significant Accounting Policies [Table]
Fair Value, Net Asset (Liability)
Fair Value, Net Asset (Liability), Total
MD Anderson License.
Md Anderson License [Member]
MD Anderson License
Related Party Transactions Disclosure [Text Block]
Related Party Transactions
2025
Lessee, Operating Lease, Liability, to be Paid, Year Two
Ares Trading [Member]
Ares Trading [Member]
ARES Trading License
Accrued Professional Fees, Current
Professional services
Statement [Line Items]
Statement [Line Items]
Accrued manufacturing costs, current.
Accrued Manufacturing Costs, Current
Manufacturing services
Eden Bio Cell
Eden Bio Cell [Member]
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Antidilutive securities excluded from computation of earnings per share, amount
Commitments and Contingencies Disclosure [Table]
Commitments and Contingencies Disclosure [Table]
Commitments and Contingencies Disclosure [Table]
Represents Aggregate Benchmark Payments Payable.
Aggregate Benchmark Payments Payable
Aggregate Benchmark Payments Payable
Lease, Cost, Total
Lease, Cost
Total lease cost
Subsequent Event [Line Items]
Warrant [Member]
Warrants [Member]
Fair value of warrants
Fair Value of Warrants
Fair Value of Warrants
Royalty fee
Royalty Expense
Royalty amount
Schedule of Deferred Tax Assets and Liabilities [Table Text Block]
Significant Component of Deferred Tax Assets
Common Stock [Member]
Common Stock [Member]
Common Stock [Member]
Debt Instrument [Line Items]
Unspecified monetary damages
Loss Contingency, Damages Sought, Value
Warrants and Rights Outstanding, Maturity Date
Warrant Expiry date
Temporary Equity, Par or Stated Value Per Share
Preferred stock, stated value
Collaboration Agreement With Solasia Pharma KK [Member]
Collaboration agreement with solasia pharma K.K.
Collaboration Agreement with Solasia Pharma K.K. [Member]
Employee Benefit and Share-based Payment Arrangement, Noncash, Total
Employee Benefit and Share-Based Payment Arrangement, Noncash
Stock-based compensation
Cash and Cash Equivalents, at Carrying Value, Ending Balance
Cash and Cash Equivalents, at Carrying Value, Beginning Balance
Cash and Cash Equivalents, at Carrying Value, Total
Cash and Cash Equivalents, at Carrying Value
Cash and cash equivalents
Cash balance
Stock Repurchased During Period, Value
Repurchase of common stock
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
Share-Based Compensation Expense Included in Statements of Operations
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value
Options exercisable, at end of period
Agreement termination notice period.
Agreement Termination Notice Period
Agreement termination, notice period
Entity Common Stock, Shares Outstanding
Antidilutive Securities, Name [Domain]
Antidilutive Securities, Name [Domain]
MD Anderson Warrant [Member]
Md Anderson Warrant Member
Md Anderson Warrant [Member]
MD Anderson Warrant [Member]
Schedule of Debt
Schedule of Debt [Table Text Block]
Cover [Abstract]
Dividends [Domain]
Dividends [Domain]
Vesting [Axis]
Document Fiscal Year Focus
Warrants exercised
Class Of Warrant Or Right Warrants Exercised
Class of warrant or right warrants exercised.
Litigation expense
Litigation Settlement, Expense
Sale of Stock [Domain]
Agreement Type Axis
Agreement Type [Axis]
Extinguishment of debt, amount
Extinguishment of Debt, Amount
Earning Per share Basic and Diluted
Earning Per share Basic and Diluted [Line Items]
Share-Based Payment Arrangement [Policy Text Block]
Accounting for Stock-Based Compensation
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value
Granted
Two Thousand Twelve Equity Incentive Plan [Member]
Two Thousand Twelve Equity Incentive Plan [Member]
the "2012 Plan" [Member]
Security Exchange Name
Ziopharm [Member]
Ziopharm [Member]
Domestic Tax Authority [Member]
Domestic Tax Authority
Tax relaxation on taxable income.
Tax Relaxation On Taxable Income
Relaxation of taxable income, percentage
New Accounting Pronouncements, Policy [Policy Text Block]
New Accounting Pronouncements
Preferred Stock, Shares Authorized
Preferred stock, shares authorized
Property, Plant and Equipment, Gross, Ending Balance
Property, Plant and Equipment, Gross, Beginning Balance
Property, Plant and Equipment, Gross, Total
Property, Plant and Equipment, Gross
Property and equipment, Gross
Treasury Stock, Shares, Acquired
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price
Cancelled
Legal Entity [Axis]
Legal Entity [Axis]
Financial Instrument [Axis]
Royalties amount payable thereafter
Royalties Amount Payable thereafter
Royalties amount payable thereafter.
Warrants fully vested upon issuance
Warrants and Rights Outstanding, Term
Stock Issued During Period, Value, Stock Options Exercised
Exercise of employee stock options
Entity Emerging Growth Company
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period, Intrinsic Value
Total intrinsic value of options
Amendment Flag
Defined Benefit Plan, Assumptions [Table Text Block]
Assumptions for Volatility, Expected life, Dividend Yield and Risk-free Interest Rate
Reduced credits carryforward
Tax Credit Carryforward, Amount
Schedule of Accrued Liabilities [Table Text Block]
Component of Accrued Expenses
Percentage of prepayments premium.
Percentage Of Prepayments Premium
Percentage of prepayments premium
Post Stock Split Shares Authorized
Post Stock Split Shares Authorized
Basis of Accounting, Policy [Policy Text Block]
Basis of Presentation
Equity Method Investment, Ownership Percentage
Equity interest in affilated entity
Consultants [Member]
Consultants [Member]
Consultants [Member]
New Warrants Member
New Warrants [Member]
Restructuring
Restructuring and Related Activities Disclosure [Text Block]
Deferred Tax Assets, Tax Deferred Expense, Compensation and Benefits, Total
Deferred Tax Assets, Tax Deferred Expense, Compensation and Benefits
Stock-based compensation
Number of warrants issued
Class of Warrant or Right, Number of Securities Called by Each Warrant or Right
Silicon Valley Bank Loan [Member]
Silicon Valley Bank loan.
Silicon Valley Bank Loan [Member]
Annual expense incurred.
Annual Expense Incurred
Annual expense incurred
Securities Act File Number
Entity File Number
Uncategorized [Abstract]
Uncategorized [Abstract]
Deferred Tax Assets, Gross
Deferred Tax Assets Gross
Cantor [Member]
Cantor [Member]
Cantor.
Term loan member
Term Loan [Member]
Operating Loss Carryforwards Expiration Dates State
Operating Loss Carryforwards Expiration Dates State
Net operating loss carryforwards, expiration date
Debt obligations
Long-term debt
Long-term debt
Long-Term Debt, Excluding Current Maturities
Cash and cash equivalents, end of period
Cash, cash equivalents and restricted cash, beginning of period
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Total
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents
Cash, cash equivalents and restricted cash
Underwriter par or stated value per share
Underwriter Par or Stated Value Per Share
Underwriter par or stated value per share.
Decrease in the carrying amount of right-of-use assets
The increase (decrease) during the period in the carrying value of right of use asset reported as assets.
Increase Decrease In Right Of Use Asset
Share-Based Payment Arrangement [Abstract]
Options Outstanding
Deferred tax assets research expenses capitalized.
Deferred Tax Assets Research Expenses Capitalized
Capitalized research expenses
Issuance of common stock, net of expenses in shares.
Issuance Of Common Stock Net Of Expenses In Shares
Issuance of common stock, net of expenses (in shares)
Accounts Payable, Current, Total
Accounts Payable, Current
Accounts payable
Debt Instrument [Axis]
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value
Ending Balance
Beginning Balance
Deferred Tax Assets, Valuation Allowance, Total
Deferred Tax Assets, Valuation Allowance
Less valuation allowance
Operating Expenses
Amounts expensed for services incurred
Total operating expenses
Public offering, net price per share
Public offering, net price per share
Issuance & sale of common stock in public offering price per share
Reduction in right-of-use assets for modification and termination
Reduction in Right of Use Assets for Modification and Termination
Reduction in right of use assets for modification and termination.
Auditor Location
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term
Expected life in years
Fair Value Assumptions Expected Term1
Stockholders equity reverse stock split
Stockholders' Equity, Reverse Stock Split
Entity Address, Address Line Two
Preferred stock, stated value
Preferred Stock, Value, Issued
Preferred Stock, Value, Issued, Ending Balance
Preferred Stock, Value, Issued, Beginning Balance
Preferred Stock, Value, Issued, Total
Entity Small Business
Entity Shell Company
Increase (Decrease) in Operating Assets [Abstract]
(Increase) decrease in:
Schedule of Nonvested Share Activity [Table Text Block]
Summary of Non-Vested Restricted Stock
Title of Individual [Axis]
Title of Individual [Axis]
Equity [Line Items]
Equity [Line Items]
Equity [Line Items]
Warrant exercise per share
Class of Warrant or Right, Exercise Price of Warrants or Rights
Warrant Exercise Per share
Employee compensation
Accrued Bonuses, Current
Non Vested Restricted Stock
Non Vested Restricted Stock [Member]
Unvested Restricted Common Stock [Member]
Class of Warrant or Right [Domain]
Share-Based Payment Arrangement, Nonvested Award, Excluding Option, Cost Not yet Recognized, Amount
Unrecognized compensation costs related to non-vested restricted stock outstanding
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value [Abstract]
Weighted Average Grant Date Fair Value
Entity Address, Address Line One
Cash and Cash Equivalents, Fair Value Disclosure
Cash equivalents
Antidilutive Securities [Axis]
Antidilutive Securities [Axis]
Loss contingency, name of plaintiff
Loss Contingency, Name of Plaintiff
Subsequent Event Type [Domain]
Subsequent Event Type [Domain]
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Minimum
Risk-free interest rate, Minimum
Gain on lease modification and termination
Gain (Loss) On Operating Lease Modification And Termination
Gain (loss) on operating lease modification and termination.
Income Statement Location [Axis]
Income Statement Location [Axis]
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Maximum
Risk-free interest rate, Maximum
Fair Value Assumptions Risk Free Interest Rate Maximum
Deferred tax liabilities:
Deferred Tax Liabilities, Net [Abstract]
Dividend rate
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate
Fair Value Assumptions Expected Dividend Rate
2028
Lessee, Operating Lease, Liability, to be Paid, Year Five
Operating Lease Area
Operating Lease Area
Operating lease area.
License Agreement With The National Cancer Institute Member
License Agreement with the National Cancer Institute [Member]
Equity Method Investments
Equity method investments
Two Thousand Twelve Stock Option Plan Member
Two Thousand Twelve Stock Option Plan [Member]
Par value per share
Share Price
Price per Share
Agreement Type Domain
Agreement Type [Domain]
Total debt
Loan and Security Agreement
Total debt
Long-Term Debt, Gross
Product and Service [Axis]
C A R Products Member
CAR Products [Member]
C A R Products [Member]
Title of 12(b) Security
Previously Reported [Member]
Previously Reported [Member]
Aggregate minimum annual royalties paid.
Aggregate Minimum Annual Royalties Paid
Aggregate minimum annual royalties paid
Lease termination date
Lease Termination Date
Lease termination date.
Clinical
Accrued clinical expenses current
Accrued clinical expenses current.
Schedule of Subsidiary or Equity Method Investee [Table]
Summary Of Significant Accounting Policies [Line Items]
Summary Of Significant Accounting Policies [Line Items]
Summary Of Significant Accounting Policies [Line Items]
Post Marketing Approval Member
Post Marketing Approval [Member]
Prepaid Expenses and Other Current Assets
Prepaid Expenses and Other Current Assets [Member]
Eligibility for bonus depreciation, percentage
Bonus Depreciation Eligibility, Percentage
Bonus Depreciation Eligibility, Percentage
Net Cash Provided by (Used in) Investing Activities [Abstract]
Cash flows from investing activities:
Amortization of financing costs
Amortization of Debt Issuance Costs
State and Local Jurisdiction [Member]
State and Local Jurisdiction
Segment Reporting, Policy [Policy Text Block]
Operating Segments
Long-Lived Tangible Asset [Domain]
Property, Plant and Equipment, Type [Domain]
Subsequent Event [Table]
The first benchmark payment due upon the initiation of the Company's first sponsored phase.
Initial Benchmark Payment Due
First benchmark payment
Houston Texas [Member]
Houston Texas [Member]
Houston, TX [Member]
Interest expense
Interest Expense, Debt
Interest Expense, Debt, Total
License agreement commencing date.
License Agreement Commencing Date
License agreement commencing date
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term
Options exercisable, at end of period
Additional number warrants issued
Additional number of warrants issued.
Additional Number Of Warrants Issued
Common Stock, Shares, Outstanding, Ending Balance
Common Stock, Shares, Outstanding, Beginning Balance
Common Stock, Shares, Outstanding
Common stock, shares outstanding
Common stock, shares outstanding
Risk-free interest rate
Risk-free interest rate
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value
Cancelled
Proceeds from Warrant Exercises
Warrant exercise, net of commissions and expenses
Issuance of common stock upon exercise of warrants, net
Tax Credit Carryforward [Axis]
Tax Credit Carryforward [Axis]
Other consulting services
Accrued consulting fees, current.
Accrued Consulting Fees, Current
Laboratory Equipment [Member]
Laboratory Equipment [Member]
Laboratory equipment [Member]
Income Statement Location [Domain]
Income Statement Location [Domain]
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Granted
Stock options granted exercise price
License Agreement Terms [Member]
Document Type
The increase (decrease) during the period in the carrying value of lease liabilities reported as liabilities.
Increase Decrease In Lease Liabilities
Lease liabilities
Accrued Payments
Commitments and Contingencies Disclosure [Line Items]
Commitments and Contingencies Disclosure [Line Items]
Accrued Payments
Sublease term commenced end date amendment.
Sublease Term Commenced End Date Amendment
Sublease term amendment
Initial borrowing
Loan and Security Agreement
Line of Credit Facility, Current Borrowing Capacity
Exercise price
Common Stock, Call or Exercise Features
Net cash provided by (used in) investing activities
Net Cash Provided by (Used in) Investing Activities
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period
Cancelled
Net cash provided by (used in) financing activities
Net Cash Provided by (Used in) Financing Activities
Debt Instrument, Redemption, Period [Domain]
Assets and Liabilities Eliminated upon Consolidation [Abstract]
Assets and Liabilities Eliminated upon Consolidation [Abstract]
Net Proceeds from Underwriting
Entity Filer Category
Deferred Tax Assets, Tax Credit Carryforwards, Research
Research and development credit carryforwards
Disclosure Of Earning Per share Basic and Diluted
Disclosure Of Earning Per share Basic and Diluted [Abstract]
Equity Method Investments and Joint Ventures Disclosure [Text Block]
Joint Venture
Balance Sheet Location [Domain]
Balance Sheet Location [Domain]
Other non-current assets
Increase (Decrease) in Other Noncurrent Assets
Increase (Decrease) in Accrued Liabilities, Total
Increase (Decrease) in Accrued Liabilities
Accrued expenses
Minimum sales revenue on which benchmark payments payable
Minimum Sales Revenue On Which Benchmark Payments Payable
Minimum sales revenue on which benchmark payments payable.
Due Date Axis
Due date [Axis]
Nonoperating Income (Expense)
Other income (expense), net
Third anniversary
Debt Instrument, Redemption, Period Three [Member]
Amounts included in accrued expenses and accounts payable related to property and equipment
Capital Expenditures Incurred but Not yet Paid
Liabilities
Total liabilities
Employees [Member]
Employees [Member]
Employees [Member]
Property, Plant and Equipment [Table]
Property, Plant and Equipment [Table]
Debt instrument description of variable rate basis
Debt Instrument, Description of Variable Rate Basis
Property and equipment and right-of-use assets impairment
Asset Impairment Charges
Asset Impairment Charges, Total
Equity, Attributable to Parent
Balance
Balance
Total stockholders' equity
Deferred Tax Liability Right of Use Asset, Total
Deferred Tax Liability Right of Use Asset.
Deferred Tax Liability Right of Use Asset
Right of use asset
Consolidated Entities [Axis]
Net loss
Net loss
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Research and Development, Percent
Research and development credits
Interest Expense, Total
Interest Expense
Interest expense
Business Description and Basis of Presentation [Text Block]
Organization
Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Percent
State income tax, net of federal tax benefit
Number of additional option available to the underwriter to purchase
Number Of Additional Option Available To The Underwriter To Purchase
Number of additional option available to the underwriter to purchase.
Fair Value Measurement, Policy [Policy Text Block]
Fair Value Measurements
Statement of Financial Position [Abstract]
Weighted average common shares outstanding, diluted
Weighted Average Number of Shares Outstanding, Diluted, Total
Weighted Average Number of Shares Outstanding, Diluted
Weighted average common shares outstanding used to compute diluted net income (loss) per share
Increase (Decrease) in Operating Liabilities [Abstract]
Increase (decrease) in:
Warrants expiration date
Warrants Expiration Date
Warrants Expiration Date
Black-Scholes Model [Member].
Black Scholes Model [Member]
Black-Scholes Model [Member]
Increase (Decrease) in Receivables, Total
Increase (Decrease) in Receivables
Receivables
Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]
Reconciliation of Income Tax Expense (Benefit)
Credit Facility [Axis]
Credit Facility [Axis]
Effective Income Tax Rate Reconciliation, Percent
Effective tax rate
Other Income and Expenses [Abstract]
Other income (expense):
Percentage of original principal due as a final payment.
Percentage of Original Principal Due as a Final Payment
Percentage of original principal due as a final payment
Weighted-average remaining lease term (years)
Operating Lease, Weighted Average Remaining Lease Term
Use of Estimates, Policy [Policy Text Block]
Use of Estimates
Income Tax Disclosure [Text Block]
Income Taxes
Debt extinguishment costs
Payment for Debt Extinguishment or Debt Prepayment Cost
Deferred Tax Assets, Net [Abstract]
Deferred tax assets:
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Ending Balance
Beginning Balance
Placement agent fees and other related expenses.
Placement Agent Fees And Other Related Expenses
Placement agent fees and other expenses
Maximum Sales Revenue On Which Benchmark Payments Payable
Maximum Sales Revenue On Which Benchmark Payments Payable
Annual salary in cash
Salary and Wage, Excluding Cost of Good and Service Sold
Salary and Wage, Excluding Cost of Good and Service Sold, Total
Leasehold Improvements [Member]
Leasehold improvements [Member]
Income Tax Authority [Axis]
Income Tax Authority [Axis]
CRADA Agreement [Member]
CRADA Agreement
CRADA Agreement [Member]
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Receivables, Net, Current, Total
Receivables, Net, Current
Receivables
Fair Value Disclosures [Abstract]
Debt Instrument, Redemption, Period One [Member]
Debt Instrument Redemption Period One
Warrants
The entire disclosure pertaining to the warrant.
Warrant [Text Block]
Fair Value Hierarchy and NAV [Axis]
Fair Value, Hierarchy [Axis]
Measurement Frequency [Domain]
Fair Value, Measurement Frequency [Domain]
Payments to Acquire Property, Plant, and Equipment, Total
Payments to Acquire Property, Plant, and Equipment
Purchases of property and equipment
Consulting service amount
Professional and Contract Services Expense
Type of Restructuring [Domain]
Class Of Warrant Or Right.
Class Of Warrant Or Right Domain [Domain]
Revision of Prior Period [Domain]
Amount of expense related to License payments.
License Expense
License Expense
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period
Vested
Common stock issuance
Issuance of common stock in connection with an at the market offering, net of commissions and expenses of $400 (Shares)
Stock Issued During Period, Shares, New Issues
Class of Warrant or Right [Axis]
Income Tax Disclosure [Abstract]
Tax Credit Carryforward, Name [Domain]
Tax Credit Carryforward, Name [Domain]
Deferred tax assets start up and pre clinical studies.
Deferred Tax Assets Start Up And Pre Clinical Studies
Start-up and pre-clinical studies