75000 - Document - Cover Page
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75010 - Statement - BALANCE SHEETS
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75020 - Statement - BALANCE SHEETS (Parenthetical)
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75030 - Statement - STATEMENTS OF OPERATIONS
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75040 - Statement - STATEMENTS OF CHANGES IN STOCKHOLDERS' EQUITY
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75050 - Statement - STATEMENTS OF CASH FLOWS
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75060 - Disclosure - Cybersecurity Risk Management, Strategy and Governance
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995457 - Disclosure - Organization
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995467 - Disclosure - Financings
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995477 - Disclosure - Summary of Significant Accounting Policies
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995487 - Disclosure - Debt
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995497 - Disclosure - Property and Equipment, net
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995507 - Disclosure - Accrued Expenses
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995517 - Disclosure - Related Party Transactions
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995527 - Disclosure - Leases
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995537 - Disclosure - Commitments and Contingencies
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995547 - Disclosure - Equity
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995557 - Disclosure - Warrants
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995567 - Disclosure - Restructuring
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995577 - Disclosure - Income Taxes
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995587 - Disclosure - Stock Option Plan
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995597 - Disclosure - Employee Benefit Plan
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995607 - Disclosure - Segment Information
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995617 - Disclosure - Joint Venture
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995627 - Disclosure - Subsequent Events
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995637 - Disclosure - Summary of Significant Accounting Policies (Policies)
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995647 - Disclosure - Summary of Significant Accounting Policies (Tables)
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995657 - Disclosure - Debt (Tables)
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995667 - Disclosure - Property and Equipment, net (Tables)
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995677 - Disclosure - Accrued Expenses (Tables)
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995687 - Disclosure - Leases (Tables)
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995697 - Disclosure - Warrants (Tables)
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995707 - Disclosure - Income Taxes (Tables)
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995717 - Disclosure - Stock Option Plan (Tables)
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995727 - Disclosure - Segment Information (Tables)
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995737 - Disclosure - Organization - Additional Information (Details)
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995747 - Disclosure - Financings - Additional Information (Detail)
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995757 - Disclosure - Summary of Significant Accounting Policies - Additional Information (Detail)
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995767 - Disclosure - Summary of Significant Accounting Policies - Assets and Liabilities Measured at Fair Value on Recurring Basis (Details)
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995777 - Disclosure - Summary of Significant Accounting Policies - Potential Dilutive Shares Excluded from Computation of Diluted Net Loss Per Share (Detail)
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995787 - Disclosure - Summary of Significant Accounting Policies - Schedule of Net loss Attributable to Common Shareholders (Details)
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995797 - Disclosure - Property and Equipment, net - Component of Property and Equipment, Net (Detail)
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995807 - Disclosure - Property and Equipment, net - Additional Information (Detail)
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995817 - Disclosure - Accrued Expenses - Component of Accrued Expenses (Details)
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995827 - Disclosure - Commitments and Contingencies - Additional Information (Details)
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995837 - Disclosure - Debt - Additional Information (Details)
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995847 - Disclosure - Related Party Transactions - Additional Information (Details)
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995857 - Disclosure - Leases - Additional Information (Details)
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995867 - Disclosure - Leases - Components of Lease Expense (Details)
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995877 - Disclosure - Leases - Operating Lease Liabilities (Details)
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995887 - Disclosure - Leases - Operating Lease Liabilities (Details) 2
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995897 - Disclosure - Equity - Additional Information (Details)
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995907 - Disclosure - Warrants - Summary of Warrant Activity (Details)
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995917 - Disclosure - Warrants - Additional Information (Details)
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995927 - Disclosure - Restructuring - Additional Information (Details)
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995937 - Disclosure - Income Taxes - Significant Component of Deferred Tax Assets (Detail)
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995947 - Disclosure - Income Taxes - Additional Information (Detail)
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995957 - Disclosure - Income Taxes - Reconciliation of Income Tax Expense (Benefit) (Detail)
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995967 - Disclosure - Income Taxes - Reconciliation of Income Tax Expense (Benefit) (Detail) 2
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995977 - Disclosure - Preferred Stock and Stockholders' Equity (Deficit) - Additional Information (Detail)
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995987 - Disclosure - Stock Option Plan - Additional information (Detail)
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995997 - Disclosure - Stock Option Plan - Share-Based Compensation Expense on All Employee and Non-Employee Awards (Detail)
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996007 - Disclosure - Stock Option Plan - Stock Option Activity Under Stock Option Plan (Detail)
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996017 - Disclosure - Stock Option Plan - Summary of Non-Vested Restricted Stock (Detail)
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996027 - Disclosure - Stock Option Plan - Assumptions for Volatility, Expected Life, Dividend Yield and Risk-Free Interest Rate (Detail)
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996037 - Disclosure - Employee Benefit Plan - Additional Information (Detail)
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996047 - Disclosure - Segment Information - Additional Information (Details)
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996057 - Disclosure - Segment Information - Summary of Segment Reporting Information (Details)
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996067 - Disclosure - Joint Venture - Additional Information (Details)
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996077 - Disclosure - Subsequent Events - Additional Information (Details)
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Additional Loans Committed
Additional Loans Committed
Additional loans committed.
Federal and State
Federal and State [Member]
Federal and State [Member]
Income Taxes [Table]
Income Taxes [Table]
Income Taxes [Table]
Volume weighted average price percentage
Volume Weighted Average Price Percentage
Volume weighted average price percentage.
Vested
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value
Vested shares, Weighted average exercise price
Clinical expenses.
Clinical Expenses
Clinical expenses
Shares issued as consideration for services (in shares)
Stock Issued During Period, Shares, Issued as consideration for services
Stock issued during period shares issued as consideration for services
Software [Member]
Software Development [Member]
Entity Incorporation, State or Country Code
Preferred Stock, Shares Issued
Shares sold
Preferred stock, shares issued
Defined benefit plan contributions by employer
Defined Benefit Plan, Plan Assets, Contributions by Employer
Annual license fee
Annual License Fees
Annual License Fees
Accounts payable
Increase (Decrease) in Accounts Payable
Increase (Decrease) in Accounts Payable, Total
Revision of Prior Period [Axis]
Long-term debt
Long-Term Debt, Excluding Current Maturities
Long-term debt
Debt obligations
Two thousand and twenty equity incentive plan [Member].
Two Thousand And Twenty Equity Incentive Plan [Member]
2020 Equity Incentive Plan [Member]
Plan Name [Axis]
Plan Name [Axis]
Equity [Abstract]
Entity Current Reporting Status
Loss Contingency, Damages Sought, Value
Unspecified monetary damages
Issuance of common stock upon exercise of warrants, net
Warrant exercise, net of commissions and expenses
Proceeds from Warrant Exercises
Capitalized acquisition costs
Deferred Tax Assets, Capitalized Acquisition Costs
Deferred tax assets capitalized acquisition costs.
Total deferred tax assets
Deferred Tax Assets, Net of Valuation Allowance
Weighted Average Exercise Price
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract]
Commitments and Contingencies
Commitments and Contingencies Disclosure [Text Block]
Common stock, shares authorized
Common Stock, Shares Authorized
Research and development credits
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Research and Development, Percent
Product and Service [Axis]
Document Fiscal Period Focus
Warrants
Warrants [Policy Text Block]
Disclosure of accounting policy for warrants.
At The Market Offering [Member]
Market Offering [Member]
At The Market Offering Member
At The Market Offering [Member]
Entity Shell Company
Class of Warrant or Right, Weighted- Average Exercise Price Granted
Class of warrant or right, weighted- average exercise price granted.
Weighted- Average Exercise Price, Granted
Other Income Expense [Member]
Other Income Expense [Member]
Other income expense member.
Operating Segments
Segment Reporting, Policy [Policy Text Block]
Cash balance
Cash and cash equivalents
Cash and Cash Equivalent
Cash and Cash Equivalents, at Carrying Value, Total
Cash and Cash Equivalents, at Carrying Value, Beginning Balance
Cash and Cash Equivalents, at Carrying Value, Ending Balance
Conditional milestone amount payable
Conditional Milestone Amount Payable
Conditional milestone amount payable.
Litigation Settlement, Fee Expense
Litigation expense
Research and Development Arrangement, Contract to Perform for Others, Type [Axis]
Cybersecurity Risk Management, Strategy, and Governance [Abstract]
Common stock, shares issued
Common Stock, Shares, Issued
Common Stock, Shares, Issued, Total
Cybersecurity Risk Management Positions or Committees Responsible Report to Board [Flag]
Cybersecurity Risk Board of Directors Oversight [Text Block]
Number of Days Option Exerciable
NumberofDaysOptionExerciable
Maximum amount of royalty payable.
Maximum Amount of Royalty Payable
Maximum royalty amount
Statement [Table]
Statement [Table]
Silicon Valley Bank [Member]
Silicon valley bank.
Silicon Valley Bank [Member]
Receivables
Increase (Decrease) in Receivables
Increase (Decrease) in Receivables, Total
Share-Based Payment Arrangement, Option, Exercise Price Range, Outstanding, Weighted Average Exercise Price
Share-Based Payment Arrangement, Option, Exercise Price Range, Outstanding, Weighted Average Exercise Price, Ending Balance
Share-Based Payment Arrangement, Option, Exercise Price Range, Outstanding, Weighted Average Exercise Price, Beginning Balance
Stock option purchase of common stock exercise price
Milestone payment made
Milestone Payment Made One
Milestone payment made One.
Statement [Line Items]
Statement [Line Items]
Aggregate Intrinsic Value
Share-based Compensation Arrangement by Share-based Payment Award, Options, Aggregate Intrinsic Value [Abstract]
Share-based Compensation Arrangement by Share-based Payment Award, Options, Aggregate Intrinsic Value [Abstract]
Warrants [Member]
Warrant [Member]
Entity Filer Category
Percentage of sub licensing income, attributable to related party.
Percentage of Sub licensing Income Payable to Related Party
Portion of income payable to related party
Number of Shares
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number of Shares [Roll Forward]
Total liabilities and stockholders' equity
Liabilities and Equity
Debt Instrument [Line Items]
Payables and Accruals [Abstract]
Impact of Topic 606 Adoption on Financial Statements
Accounting Standards Update and Change in Accounting Principle [Table Text Block]
Options exercisable, at end of period
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price
Reimbursement of historical costs
Aggregate Amount Potentially Reimburseable Amount
Aggregate Amount Potentially Reimburseable Amount.
Property, Plant and Equipment, Type [Axis]
Long-Lived Tangible Asset [Axis]
Severance costs
Severance Costs
Termination benefits
Underwriting Agreement [Member]
Underwriting Agreement [Member]
Underwriting Agreement
Valuation Allowance, Deferred Tax Asset, Increase (Decrease), Amount
Increase (decrease) in deferred tax assets
Cybersecurity Risk Third Party Oversight and Identification Processes [Flag]
Net operating loss carryforwards, expiration date
Operating Loss Carryforwards Research Expiration Dates
Operating Loss Carryforwards Research Expiration Dates
Deferred Revenue [Domain]
Cash and Cash Equivalents, Fair Value Disclosure
Cash equivalents
Maximum amount of additional milestones payable.
Maximum Amount of Additional Milestones Payable
Expected additional milestones payable
Less valuation allowance
Deferred Tax Assets, Valuation Allowance
Deferred Tax Assets, Valuation Allowance, Total
Extinguishment of Debt, Amount
Extinguishment of debt, amount
Federal income tax at statutory rates
Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent
Shares price, per share
Shares Issued, Price Per Share
Subsequent Event [Line Items]
Cybersecurity Risk Management Third Party Engaged [Flag]
Sublease area.
Sublease Area
Sublease Area
Documents Incorporated by Reference
Documents Incorporated by Reference [Text Block]
Effective tax rate
Effective Income Tax Rate Reconciliation, Percent
Income Tax Authority [Axis]
Income Tax Jurisdiction [Axis]
Deferred Tax Assets, Operating Loss Carryforwards, Not Subject to Expiration
Deferred tax assets operating loss carryforwards without expire date
Geographical [Domain]
Geographical [Domain]
Lease liability
Deferred Tax Assets Lease Liability
DeferredTaxAssetsLeaseLiability.
Pre Funded Warrants [Member]
Pre funded warrants.
Pre Funded Warrants [Member]
Agreement Type Axis [Axis]
Agreement Type Axis Axis
Prepaid Expense and Other Assets, Noncurrent
Prepaid expenses and other assets, non current
Other long-term assets
Additional paid-in capital
Additional Paid in Capital, Common Stock
Additional Paid in Capital, Common Stock, Beginning Balance
Additional Paid in Capital, Common Stock, Ending Balance
Debt Issuance Costs, Net
Debt Issuance Costs, Net, Total
Issuance costs
Boston, MA [Member]
MA [Member]
MA
Mr. Hogue
Hogue [Member]
Mr. Hogue.
Summary of Significant Accounting Policies
Significant Accounting Policies [Text Block]
Property, Plant and Equipment [Line Items]
Property, Plant and Equipment [Line Items]
Measurement Input, Risk Free Interest Rate [Member]
Risk-free Interest Rate
Lab equipment.
Lab Equipment [Member]
Lab Equipment [Member]
Vesting [Domain]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross
Stock option granted
Common stock shares awarded
Cybersecurity Risk Management, Strategy, and Governance [Table]
Schedule of Net Loss Attributable to Common Shareholders
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Research and Development, Amount
Research and development credits, Amount
Investment, Name [Axis]
Net loss per share, basic
Net loss per share, basic
Net income (loss) per share, basic
Earnings per share, Basic
Outstanding options issued
Beginning Balance
Ending Balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number
Salary and Wage, Officer, Excluding Cost of Good and Service Sold
Annual base salary
Total current liabilities
Liabilities, Current
Adjustments to reconcile net loss to net cash used in operating activities:
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity [Abstract]
Lessee, Operating Lease, Liability, to be Paid, Year Five
2028
Salary and Wage, Excluding Cost of Good and Service Sold, Total
Salary and Wage, Excluding Cost of Good and Service Sold
Annual salary in cash
Gain (Loss) On Modification Of Lease
Gain (Loss) On Modification Of Lease
Gain (loss) on modification of lease.
Domestic Tax Jurisdiction [Member]
Domestic Tax Authority [Member]
Subscription Arrangement [Member]
Subscription Arrangement [Member]
Consolidation Items [Domain]
Equity, Attributable to Parent [Abstract]
Stockholders' equity
Entity Small Business
Accrued expenses
Increase (Decrease) in Accrued Liabilities
Increase (Decrease) in Accrued Liabilities, Total
Accumulated deficit
Retained Earnings (Accumulated Deficit)
Retained Earnings (Accumulated Deficit), Total
Retained Earnings (Accumulated Deficit), Beginning Balance
Retained Earnings (Accumulated Deficit), Ending Balance
Accumulated deficit
Preferred Stock [Member]
Preferred Stock
Depreciation
Deferred Tax Assets, Depreciation
Deferred tax assets depreciation.
Entity Well-known Seasoned Issuer
Deferred Tax Assets, Operating Loss Carryforwards, Subject to Expiration
Deferred tax assets operating loss carryforwards with expire date
Cancelled
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period
Warrants and Rights Outstanding, Measurement Input
Warrant, measurement input
Sale Of Series A One Preferred Stock Shares
Sale of series a one preferred stock shares.
Sale of Series A-1 preferred stock (in shares)
Financings
Financing Arrangements Disclosure [Text Block]
Includes disclosures related to financing receivables and financing guarantees in which the company is the guarantor.
Amendment Flag
Warrant Floor Price
Warrant floor price.
Warrant Floor Price
Product and Service [Domain]
Effective Income Tax Rate Reconciliation at Federal Statutory Income Tax Rate, Amount
Federal income tax at statutory rates, Amount
Number of warrants
Warrants to purchase common stock
Warrants to purchase common stock
Chief Executive Officer [Member]
Chief Executive Officer [Member]
Net Loss per Share
Earnings Per Share, Policy [Policy Text Block]
LIABILITIES, PREFERRED STOCK AND STOCKHOLDERS' EQUITY
Liabilities and Equity [Abstract]
Entity Address, Postal Zip Code
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation
Net cash flows from operating activities
Sale Common Stock Over Period
Sale common stock over period.
Sale Common Stock Period
Segment Reporting, CODM, Profit (Loss) Measure, How Used, Description
Common Stock [Member]
Common Stock [Member]
Common Stock
Deferred board service fee
Deferred Board Service Fees
Deferred board service fees .
Cybersecurity Risk Role of Management [Text Block]
Reduced credits carryforward
Tax Credit Carryforward, Amount
Number Of share Exercised
Class of Warrants or Right Exercised
Class of warrants or right exercised.
Stock options granted exercise price
Granted
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Lessee, Operating Lease, Liability, to be Paid, Year Three
2026
Less: accumulated depreciation
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Total
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Beginning Balance
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Ending Balance
Payments due prior to the first marketing approval
Accruals Prior to First Marketing Approval
Payments due prior to the first marketing approval for TCR products.
Eden Biocell [Member]
Eden Biocell.
Research and Development Arrangement, Contract to Perform for Others, Type [Domain]
Entity Address, Address Line One
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
Assumptions for Volatility, Expected Life, Dividend Yield and Risk-Free Interest Rate
Fair Value Hierarchy and NAV [Axis]
Income Taxes
Income Tax, Policy [Policy Text Block]
Cybersecurity Risk Materially Affected or Reasonably Likely to Materially Affect Registrant [Flag]
Supplementary disclosure of cash flow information:
Supplemental Cash Flow Information [Abstract]
Underwriting Agreement with Jefferies [Member]
Underwriting Agreement with Jefferies [Member]
Underwriting Agreement With Jefferies Member
Operating Lease, Right-of-Use Asset
Right-of-use assets
Tax liability
Deferred Tax Liability Not Recognized, Amount of Unrecognized Deferred Tax Liability, Bad Debt Reserve for Tax Purposes of Qualified Lender
Deferred Tax Assets Gross
Deferred Tax Assets, Gross
Cybersecurity Risk Board Committee or Subcommittee Responsible for Oversight [Text Block]
Debt Instrument, Redemption, Period [Axis]
Class of Warrant or Right [Axis]
Document Type
Type of Arrangement and Non-arrangement Transactions [Axis]
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Arrangements and Non-arrangement Transactions [Domain]
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Entity Central Index Key
Cybersecurity Risk Process for Informing Board Committee or Subcommittee Responsible for Oversight [Text Block]
Agreement Termination Effective Date
Agreement termination effective date.
Agreement termination effective date
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Including Exchange Rate Effect and Discontinued Operation
Net increase (decrease) in cash, cash equivalents
Subsequent Event Type [Domain]
Subsequent Event Type [Domain]
Change in fair value of warrant liability
Fair Value Adjustment of Warrants
Change in fair value of warrant liability
Antidilutive securities excluded from computation of earnings per share, amount
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
the "2020 Plan" [Member]
Two Thousand Twenty Equity Incentive Plan [Member]
Two thousand twenty equity incentive plan.
Initial Public Offering of Common Stock
Common Stock, Par or Stated Value Per Share
Common stock, par value
Share Subscription Agreement [Member]
Share Subscription Agreement
Term A Tranche [Member]
Share-Based Payment Arrangement, Tranche One [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term
Outstanding, period
Administrative Fees Expense
Strategic and advisory services fee
Fair Value Assumptions Expected volatility Rate Maximum
Expected volatility, Maximum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Maximum
Non Vested Stock [Member]
Non Vested Stock [Member]
Non-Vested Stock [Member]
Gain (Loss) on Termination of Lease
Gain on lease termination
Gain on lease modification and termination
Document Financial Statement Error Correction [Flag]
Exercised
Exercise of employee stock options (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period
Debt Disclosure [Abstract]
Federal/state rate change
Effective Income Tax Rate Reconciliation Nondeductible Expense Federal Rate Change
Effective income tax rate reconciliation nondeductible expense federal rate change.
Total
Accrued expenses
Accrued Liabilities, Current
Current Fiscal Year End Date
Schedule of Long-Term Debt Instruments [Table]
Uncertain tax positions adjustment
Adjustments to Uncertain Tax Positions
Adjustments to uncertain tax positions.
Preferred Stock, Amount of Preferred Dividends in Arrears
Undeclared cumulative dividends
Entity Address, State or Province
Beginning Balance
Ending Balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number
Share-based payment award, unvested shares
Intrexon Corporation [Member]
Intrexon Corporation/Precigen
Intrexon Corporation/Precigen [Member]
Intrexon Corporation Member
Investment, Name [Domain]
Preferred stock, shares outstanding
Preferred Stock, Shares Outstanding
Preferred Stock, Shares Outstanding, Ending Balance
Preferred Stock, Shares Outstanding, Beginning Balance
Research and Development Costs
Research and Development Expense, Policy [Policy Text Block]
Common Stock, shares reserved for future issuance
Common stock reserved for future issuance
Common Stock, Capital Shares Reserved for Future Issuance
Defined Benefit Plan, Assumptions [Table Text Block]
Assumptions for Volatility, Expected life, Dividend Yield and Risk-free Interest Rate
Class of Warrant or Right [Domain]
Geographical [Axis]
Geographical [Axis]
Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Amount
State income tax, net of federal tax benefit, Amount
Share-Based Compensation Expense Included in Statements of Operations
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
Series A Two Preferred Stock [Member]
Series A two preferred stock.
Series A Two Preferred Stock [Member]
Series A-2 Preferred Stock
Preferred Stock, Redemption Price Per Share
Preferred stock price per share
Significant Component of Deferred Tax Assets
Schedule of Deferred Tax Assets and Liabilities [Table Text Block]
Equity Option [Member]
Stock Option [Member]
Sale Of Series A One Preferred Stock Value
Sale of series a one preferred stock value.
Sale of Series A-1 preferred stock
Subsequent Event [Member]
Subsequent Event [Member]
Securities Purchase Agreement [Member]
Securities Purchase Agreement.
Securities Purchase Agreement [Member]
Property, Plant and Equipment [Abstract]
Research and development credit carryforwards
Deferred Tax Assets, Tax Credit Carryforwards, Research
Measurement Input, Expected Term [Member]
Expected Term
Deferred Revenue Arrangement Type [Axis]
Antidilutive Securities [Axis]
Antidilutive Securities [Axis]
Subsidiary or Equity Method Investee [Line Items]
Interest Expense, Debt
Interest Expense, Debt, Total
Interest expense
State and Local Jurisdiction
State and Local Jurisdiction [Member]
Sale of Series A-2 preferred stock (in shares)
Sale Of Series A Two Preferred Stock Shares
Sale of series a two preferred stock shares.
Common stock options [Member]
Common stock options [Member]
Common stock options.
Lessee, Operating Lease, Option to Extend
Lease term, description
Description of payment terms
Line of Credit Facility, Frequency of Payment and Payment Terms
Preferred Stock, Value, Issued, Ending Balance
Preferred Stock, Value, Issued, Total
Preferred Stock, Value, Issued, Beginning Balance
Preferred Stock, Value, Issued
Preferred stock, stated value
Preferred stock value
Loss Contingency Accrual, Payments
Contingency accrual, payments
Due date [Domain]
Due Date Domain
Minimum [Member]
Minimum [Member]
Minimum
Granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value
Financial Instrument [Axis]
Current assets:
Assets, Current [Abstract]
Common stock issued for services rendered
Common Stock Issued for Services Rendered
Common stock issued for services rendered.
Payments to Fund Long-term Loans to Related Parties
Payments to Fund Long-Term Loans to Related Parties
Class of Warrant or Right, Number of Securities Called by Each Warrant or Right
Number of warrants issued
Convertible preferred stock aggregate purchase price
Convertible Preferred Stock Purchase Price
Convertible preferred stock purchase price.
License term expiration period
License Term Expiration Period
License term expiration period.
Segment Reporting [Abstract]
Assets and Liabilities Measured at Fair Value on Recurring Basis
Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block]
Current liabilities:
Liabilities, Current [Abstract]
Restructuring and Related Activities Disclosure [Text Block]
Restructuring
Office and computer equipment [Member]
Office And Computer Equipment [Member]
Office and Computer Equipment [Member].
Related Party Transactions [Abstract]
Balance (in shares)
Balance (in shares)
Shares, Outstanding
Termination costs
Termination costs
Termination Costs
Commitments and Contingencies
Commitments and contingencies (Note 5)
Stock-based compensation
Deferred Tax Assets, Tax Deferred Expense, Compensation and Benefits
Deferred Tax Assets, Tax Deferred Expense, Compensation and Benefits, Total
Beginning Balance
Ending Balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value
General and Administrative [Member]
General and Administrative Expense [Member]
Present value of lease payments
Operating Lease, Liability
Operating Lease, Liability, Total
Auditor Firm ID
Debt Instrument, Basis Spread on Variable Rate
Line of credit facility, interest rate
Preferred Stock, Dividend Rate, Percentage
Percentage of preferred stock dividends payablein shares
Series A-2 Preferred Stock [Member]
Series A-2 preferred stock.
Series A-2 Preferred Stock [Member]
Lessee, Lease, Description [Table]
Change in valuation allowance
Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Percent
Text Block [Abstract]
Debt instrument, initial maturity date
Debt Instrument, Maturity Date Range, Start
Accrued Income Taxes, Current
Sales and use taxes
Cybersecurity Risk Management Positions or Committees Responsible [Text Block]
Weighted average common shares outstanding used to compute basic net income (loss) per share
Weighted Average Number of Shares Outstanding, Basic
Weighted Average Number of Shares Outstanding, Basic, Total
Weighted average common shares outstanding, basic
Warrants Disclosure [Abstract]
Warrants Disclosure Abstract
Options exercisable, at end of period
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value
Leases, Operating [Abstract]
Reconciliation of Income Tax Expense (Benefit)
Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]
Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table]
Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]
Property, Plant and Equipment, Type [Domain]
Long-Lived Tangible Asset [Domain]
Stock options, granted
Granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Net of Forfeitures
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Net of Forfeitures, Total
Cybersecurity Risk Process for Informing Management or Committees Responsible [Text Block]
Deferred tax assets:
Deferred Tax Assets, Net [Abstract]
Subsequent Events
Subsequent Events [Text Block]
Accrued preclinical services current.
Accrued Preclinical Services Current
Preclinical services
Preclinical services
Series 1 Preferred Stock
Series 1 Preferred Stock [Member]
Series 1 Preferred Stock [Member]
Effective Income Tax Rate Reconciliation Nondeductible Expense Federal Rate Change, Amount
Effective Income Tax Rate Reconciliation Nondeductible Expense Federal Rate Change, Amount
Federal/state rate change, Amount
Related Party Transactions
Related Party Transactions Disclosure [Text Block]
Shares of authorized capital stock
Shares Authorized
The maximum number of shares permitted to be issued by an entity's charter and bylaws.
Stock-based compensation
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition
APIC, Share-based Payment Arrangement, Increase for Cost Recognition, Total
Recognition Of Warrant Liability In Connection With ELOC Agreement
Recognition of warrant liability in connection with ELOC agreement.
Recognition of warrant liability in connection with the equity line of credit agreement
Change in valuation allowance, Amount
Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Amount
Total stockholders' equity
Balance
Balance
Equity, Attributable to Parent
Preferred stock, par value
Preferred Stock, Par or Stated Value Per Share
Preferred stock par value or stated value
Basis of Presentation
Basis of Accounting, Policy [Policy Text Block]
Tri Arm [Member]
Tri Arm
Statement of Stockholders' Equity [Abstract]
Share-Based Payment Arrangement, Tranche Two [Member]
Term B Tranche [Member]
Equity method investments
Equity Method Investments
Use of Estimates
Use of Estimates, Policy [Policy Text Block]
Stock Option Plan
Stock Options And Restricted Stock Awards Text Block [Text Block]
Stock Options and Restricted Stock Awards.
Leasehold improvements [Member]
Leasehold Improvements [Member]
Entity Address, Address Line Two
Disclosure of Share-Based Compensation Arrangements by Share-Based Payment Award [Table Text Block]
Share-Based Compensation Expense on All Employee and Non-Employee Awards
Number of Shares
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding [Roll Forward]
Component of Accrued Expenses
Schedule of Accrued Liabilities [Table Text Block]
Debt Instrument, Name [Domain]
Noncash Investing and Financing Items [Abstract]
Noncash financing activities:
Segment Reporting, CODM, Individual Title and Position or Group Name [Extensible Enumeration]
Termination Date of CRADA Agreement
Agreement Termination Date
Agreement termination date
Plan Name [Domain]
Plan Name [Domain]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Entity [Domain]
Entity [Domain]
Prepaid Expenses And Other Current Assets [Policy Text Block]
Disclosure of accounting policy for its prepaid expenses and other current assets.
Prepaid Expenses and Other Current Assets
Credit Facility [Axis]
Credit Facility [Axis]
Equity interest in affilated entity
Equity Method Investment, Ownership Percentage
Cybersecurity Risk Materially Affected or Reasonably Likely to Materially Affect Registrant [Text Block]
Organization
Business Description and Basis of Presentation [Text Block]
Cybersecurity Risk Management Expertise of Management Responsible [Text Block]
Dune Lake Capital
Dune Lake Capital [Member]
Dune Lake Capital
Income Taxes [Line Items]
Income Taxes [Line Items]
Income Taxes [Line Items]
Number of Shares, Beginning Balance
Class of Warrant or Right, Outstanding
Number of Shares, Ending Balance
Weighted Average Contractual Term (Years)
Share-based Compensation Arrangement by Share-based Payment Award, Options, Weighted Average Remaining Contractual Term [Abstract]
Share-based Compensation Arrangement by Share-based Payment Award, Options, Weighted Average Remaining Contractual Term [Abstract]
Related Party [Axis]
Related and Nonrelated Parties [Axis]
Class of Warrant or Right [Table]
Property and Equipment
Property, Plant and Equipment, Policy [Policy Text Block]
Entity Address, City or Town
Schedule of Earnings Per Share, Diluted, by Common Class, Including Two Class Method
Schedule of Earnings Per Share, Diluted, by Common Class, Including Two Class Method [Table Text Block]
MD Anderson [Member]
MD Anderson [Member]
MD Anderson [Member]
Percentage of commission on gross proceeds from sale of common stock
Percentage Of Commission On Gross Proceeds From Sale Of Common Stock
Percentage Of Commission On Gross Proceeds From Sale Of Common Stock
Security Exchange Name
Credit Facility [Domain]
Credit Facility [Domain]
Property and equipment, Gross
Property, Plant and Equipment, Gross
Property, Plant and Equipment, Gross, Total
Property, Plant and Equipment, Gross, Beginning Balance
Property, Plant and Equipment, Gross, Ending Balance
Stock-based compensation
Employee Benefit and Share-Based Payment Arrangement, Noncash
Employee Benefit and Share-based Payment Arrangement, Noncash, Total
Milestone maximum payment
Milestone Payments, Maximum Amount
Milestone payments maximum amount.
Board of Directors [Member]
Board of directors.
Board of Directors [Member]
Measurement Input Type [Domain]
Antidilutive Securities, Name [Domain]
Antidilutive Securities, Name [Domain]
Cash, cash equivalents and restricted cash
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Total
Cash and cash equivalents, end of period
Cash and cash equivalents, beginning of period
Interest Paid, Excluding Capitalized Interest, Operating Activity
Cash paid for interest
Range [Domain]
Statistical Measurement [Domain]
Class of Warrant or Right, Exercise Price of Warrants or Rights
Warrant exercise per share
Weighted- Average Exercise Price Outstanding
Weighted- Average Exercise Price Outstanding
Weighted- Average Exercise Price Outstanding
Total current assets
Assets, Current
Document Period End Date
Other income (expense):
Other Income and Expenses [Abstract]
Stock offered during period shares.
Stock Offered During Period Shares
Stock issued during period
Equity Method Investments and Joint Ventures [Abstract]
Title of Individual [Axis]
Title and Position [Axis]
Fair Value Hierarchy and NAV [Domain]
ICFR Auditor Attestation Flag
Options exercisable, at end of period
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number
Stock Options and Restricted Stock [Member]
Employee Stock Option And Restricted Stock Member
Employee stock option and Restricted stock.
Debt Instrument, Description of Variable Rate Basis
Debt instrument description of variable rate basis
Statement of Financial Position [Abstract]
Restricted Stock Units (RSUs) [Member]
Revenue Recognition from Collaboration Agreements
Revenue [Policy Text Block]
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table]
Antidilutive Security, Excluded EPS Calculation [Table]
Vesting [Axis]
Class of Stock [Axis]
Class of Stock [Axis]
Total deferred tax liabilities
Deferred Tax Liabilities, Net
Deferred Tax Liabilities, Net, Total
Employee Benefit Plan
Compensation and Employee Benefit Plans [Text Block]
Cybersecurity Risk Management, Strategy, and Governance [Line Items]
Warrant Expiry date
Warrants and Rights Outstanding, Maturity Date
Warrant expiry date
Liabilities
Total liabilities
Operating expenses:
Operating Costs and Expenses [Abstract]
Less segment expenses:
Financial Instruments [Domain]
Measurement Input, Exercise Price [Member]
Excercise Price
The University of Texas MD Anderson Cancer Center and The Texas A & M University System [Member]
The University Of Texas M D Anderson Cancer Center And The Texas A And M University System [Member]
The University Of Texas M D Anderson Cancer Center And The Texas A And M University System
Payment under license agreement.
Payment Under License Agreement
Payment under license agreement
Warrants issued
Debt Conversion, Converted Instrument, Warrants or Options Issued
Threshold commitment period for exercise of rights to participate in future offerings.
Threshold Commitment Period for Exercise of Rights to Participate in Future Offerings
Threshold period for exercise or conversion of stock
Lessee, Operating Lease, Liability, to be Paid, Year Two
2025
Unvested Restricted Stock [Member]
Restricted Stock [Member]
Restricted Stock [Member]
Class of Warrant or Right, Weighted- Average Exercise Price Exercised
Class of warrant or right, weighted- average exercise price exercised.
Weighted- Average Exercise Price, Exercised
Weighted average common shares outstanding used to compute diluted net income (loss) per share
Weighted Average Number of Shares Outstanding, Diluted
Weighted Average Number of Shares Outstanding, Diluted, Total
Weighted average common shares outstanding, diluted
Entity File Number
Securities Act File Number
Class of Warrants or Right Granted
Class of warrants or right granted.
Number of Share Granted
Cover [Abstract]
Expected volatility, Minimum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Minimum
Measurement Input Type [Axis]
Research and development true-up
Effective Income Tax Rate Reconciliation Nondeductible Expense Research and Development True Up
Effective income tax rate reconciliation nondeductible expense research and development true up.
Additional Paid in Capital, Common Stock [Member]
Value received from shareholders in common stock-related transactions that are in excess of par value or stated value and amounts received from other stock-related transactions. Includes only common stock transactions (excludes preferred stock transactions). May be called contributed capital, capital in excess of par, capital surplus, or paid-in capital.
Additional Paid In Capital
Prepaid expenses and other current assets
Prepaid Expense and Other Assets, Current
Prepaid expenses and other current assets, current
Cancelled
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period
Amount of prepayments premium
Amount Of Prepayments Premium
Amount Of Prepayments Premium.
Aggregate potential benchmark payments
Aggregate potential benchmark payments
Aggregate potential benchmark payments.
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Authorized
Common stock awarded
Share-based payment award, number of shares authorized
Sale of Stock [Domain]
Professional and Contract Services Expense
Consulting service amount
Segment Information
Segment Reporting Disclosure [Text Block]
General and administrative
General and Administrative Expense
General and Administrative Expense, Total
Equity Purchase Agreement [Member]
Equity purchase agreement.
Equity Purchase Agreement
Preferred Stock, Convertible, Conversion Price
Preferred stock conversion price
Subsequent Event [Table]
Equity distribution agreement.
Equity Distribution Agreement [Member]
Equity Distribution Agreement [Member]
Other
Deferred Tax Assets, Other
Schedule of Warrant Activity [Table Text Block]
Schedule of warrant activity.
Summary of Warrant Activity
Schedule Of Equity [Table]
Schedule Of Equity [Table]
Schedule Of Equity [Table]
Property and equipment useful life
Property, Plant and Equipment, Useful Life
New Accounting Pronouncements
New Accounting Pronouncements, Policy [Policy Text Block]
Lessee, Operating Lease, Liability, Maturity
Lessee, Operating Lease, Liability, to be Paid, Maturity [Table Text Block]
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Summary Of Significant Accounting Policies [Table]
Summary Of Significant Accounting Policies [Table]
Summary Of Significant Accounting Policies [Table]
Extended term of agreement
Extended Term of Agreement
Extended term of agreement.
Consulting Services [Member]
Consulting services.
Consulting Services [Member]
Risk-free interest rate, Minimum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Minimum
Depreciation
Depreciation
Depreciation, Total
Share-Based Payment Arrangement, Nonvested Award, Excluding Option, Cost Not yet Recognized, Amount
Unrecognized compensation costs related to unvested restricted stock outstanding
Unrecognized Tax Benefits, Income Tax Penalties and Interest Expense
Unrecognized Tax Benefits, Income Tax Penalties and Interest Expense, Total
Interest and penalties
Eden Bio Cell [Member]
Eden Bio Cell
Common stock, shares outstanding
Common stock, shares outstanding
Common Stock, Shares, Outstanding
Common Stock, Shares, Outstanding, Beginning Balance
Common Stock, Shares, Outstanding, Ending Balance
Operating Lease, Liability, Current
Recognition in exchange of Operating Lease Liabilities
Series A One Preferred Stock [Member]
Series A one preferred stock.
Series A-1 Preferred Stock
Series A One Preferred Stock [Member]
Dividends [Domain]
Dividends [Domain]
Cybersecurity Risk Management Processes Integrated [Flag]
Document Transition Report
Net deferred taxes
Deferred Tax Assets, Net
Total operating expenses
Amounts expensed for services incurred
Operating Expenses
Commitments and Contingencies Disclosure [Table]
Commitments and Contingencies Disclosure [Table]
Commitments and Contingencies Disclosure [Table]
Research and development expense
Research and development
Research and Development Expense
Research and Development Expense, Total
Leases
Lessee, Operating Leases [Text Block]
Series A-1 Preferred Stock [Member]
Series A-1 preferred stock.
Series A-1 Preferred Stock [Member]
Statement of Cash Flows [Abstract]
Weighted Average Grant Date Fair Value
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value [Abstract]
Aggregate offering price
Stock Issued During Period, Value, New Issues
Issuance of common stock in registered direct offering, net of offering costs
Share-Based Payment Arrangement, Option, Activity [Table Text Block]
Stock Option Activity Under Stock Option Plan
Stock-based compensation
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Share-Based Payment Arrangement, Percent
Equity [Text Block]
Equity
Measurement Input, Expected Dividend Rate [Member]
Dividend Rate
Cybersecurity Risk Management Processes Integrated [Text Block]
Collaboration agreement with solasia pharma K.K.
Collaboration Agreement With Solasia Pharma KK [Member]
Collaboration Agreement with Solasia Pharma KK [Member]
Net loss
Net loss
Share - Based Compensation Arrangement by Share - Based Payment Award , Options , Vested in Period , Exercise Price
Share based compensation arrangement by share based payment award options vested in period exercise price .
Fully vested stock options at exercise price
Outstanding, at end of period
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value
Outstanding, at beginning of period
Outstanding, at end of period
Operating lease cost
Operating Lease, Cost
Warrants and Rights Outstanding, Term
Warrants fully vested upon issuance
Weighted- Average Contractual Term (Years)
Convertible preferred stock designated shares
Preferred Stock, Convertible, Shares Issuable
Gross Net Operating Loss
Gross net operating loss.
Gross net operating loss
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate
Dividend rate
Expected dividend yield
Operating Lease, Payments
Operating Lease, Payments
ASSETS
Assets [Abstract]
Construction-in-process
Construction in Progress [Member]
Prepaid expenses and other current assets
Increase (Decrease) in Prepaid Expense and Other Assets
Increase (Decrease) in Prepaid Expense and Other Assets, Total
Restructuring and Related Activities [Abstract]
Document Fiscal Year Focus
Cash flows from investing activities:
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation [Abstract]
Retirement Benefits [Abstract]
Accounts payable
Accounts Payable, Current
Accounts Payable, Current, Total
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested in Period, Fair Value
Fully vested stock options with aggregate fair value
Research and Development [Member]
Research and Development Expense [Member]
Agreement Type [Axis]
Agreement Type Axis
Proceeds From Sale Of Series A-2 Preferred Stock
Proceeds from sale of series A-2 preferred stock.
Proceeds from sale of Series A-2 preferred stock
Subsidiary or Equity Method Investee, Sale of Stock [Table]
Research Tax Credit Carryforward
Research Tax Credit Carryforward [Member]
Revision of Prior Period [Domain]
the "2012 Plan" [Member]
Two Thousand Twelve Equity Incentive Plan [Member]
Two Thousand Twelve Equity Incentive Plan [Member]
Fair Value Measurement, Policy [Policy Text Block]
Fair Value Measurements
Ziopharm [Member]
Ziopharm [Member]
Ziopharm [Member]
Proceeds from stock options exercised
Proceeds from Stock Options Exercised
Sale of common stock
Fair Value Disclosures [Abstract]
Commitments and Contingencies Disclosure [Abstract]
Measurement Input, Share Price [Member]
Share Price
Lessee, Operating Lease, Liability, to be Paid, Year One
2024
FLORIDA
Florida [Member]
Sale of stock consideration received on transaction
Sale of Stock, Consideration Received on Transaction
Issuance of common stock in connection with a public offering, net
Net loss attributable to common stockholders
Net Income (Loss) Available to Common Stockholders, Basic
Debt Instrument [Axis]
Derivative Instrument [Axis]
Thereafter
Lessee, Operating Lease, Liability, to be Paid, after Year Five
Options Outstanding
Share-Based Payment Arrangement [Abstract]
At The Market Offering [Member]
Sale of Stock [Axis]
Derivative Liabilities
Derivatives, Policy [Policy Text Block]
Joint Venture
Equity Method Investments and Joint Ventures Disclosure [Text Block]
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation
Net cash flows from investing activities
Title of 12(b) Security
Schedule of Segment Reporting Information, by Segment [Table]
Deferred Tax Liabilities, Net [Abstract]
Deferred tax liabilities:
Stock-based compensation, Amount
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Share-Based Payment Arrangement, Amount
Proceeds From Sale Of Series A-1 Preferred Stock
Proceeds from sale of series A-1 preferred stock.
Proceeds from sale of Series A-1 preferred stock
Cancelled
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price
Cancelled
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value
Forfeitured shares, Weighted average exercise price
Related Party [Domain]
Related and Nonrelated Parties [Domain]
Percentage Of Prepayments Premium
Percentage of prepayments premium.
Percentage of prepayments premium
Income Taxes
Income Tax Disclosure [Text Block]
Collaborative Arrangement and Arrangement Other than Collaborative [Table]
Class of Warrant or Right [Line Items]
Consultants [Member]
Consultants [Member]
Consultants [Member]
Debt Instrument, Redemption, Period [Domain]
Consolidated Entities [Axis]
Legal Entity [Axis]
Legal Entity [Axis]
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Increase (Decrease) in Operating Capital [Abstract]
Changes in operating assets and liabilities:
Component of Property and Equipment, Net
Property, Plant and Equipment [Table Text Block]
Beginning Balance
Ending Balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Silicon Valley Bank Loan [Member]
Silicon Valley Bank loan.
Silicon Valley Bank Loan [Member]
Income Tax Disclosure [Abstract]
Fair Value, Recurring and Nonrecurring [Table]
Annual expense incurred
Annual Expense Incurred
Annual expense incurred.
Shares issued as consideration for board service fees
Stock Issued During Period, Value, Issued for Services
Grant date fair value
Measurement Frequency [Domain]
Uncategorized [Abstract]
Uncategorized [Abstract]
Income Statement Location [Axis]
Statement of Income Location, Balance [Axis]
Trading Symbol
Cantor.
Cantor [Member]
Cantor [Member]
Property and Equipment, net
Property, Plant and Equipment Disclosure [Text Block]
Stock Issued During Period, Value, Issued as Consideration for Services
Stock issued during period value issued as consideration for services.
Shares issued as consideration for services
Term Loan [Member]
Term loan member
Schedule of Related Party Transactions, by Related Party [Table]
Related Party Transaction [Table]
Net operating loss carryforwards, expiration date
Operating Loss Carryforwards Expiration Dates State
Operating Loss Carryforwards Expiration Dates State
Fair Value Assumptions Risk Free Interest Rate Maximum
Risk-free interest rate, Maximum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Maximum
Effective Income Tax Rate Reconciliation, Nondeductible Expense Research and Development True Up, Amount
Effective Income Tax Rate Reconciliation, Nondeductible Expense Research and Development True Up, Amount
Research and development true-up, Amount
Director [Member]
Non-Employee Director [Member]
Subsequent Event Type [Axis]
Subsequent Event Type [Axis]
Underwriter par or stated value per share.
Underwriter Par or Stated Value Per Share
Underwriter par or stated value per share
Cash flows from financing activities:
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract]
Expected life in years
Fair Value Assumptions Expected Term1
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term
Fair Value, Recurring [Member]
Fair Value, Measurements, Recurring [Member]
Accrued Expenses
Accounts Payable and Accrued Liabilities Disclosure [Text Block]
Capitalized research expenses
Deferred Tax Assets Research Expenses Capitalized
Deferred tax assets research expenses capitalized.
Total lease payments
Lessee, Operating Lease, Liability, to be Paid
Lessee, Operating Lease, Liability, Undiscounted Excess Amount
Less: imputed interest
Periodic payment for agreement settlement
Agreement Settlement Periodic Payment
Agreement settlement periodic payment.
Equity Components [Axis]
Equity Components [Axis]
Other income (expense), net
Nonoperating Income (Expense)
Equity Component [Domain]
Equity Component [Domain]
Issuance & sale of common stock in public offering price per share
Public offering, net price per share
Public offering, net price per share
Reduction in Right of Use Assets for Modification and Termination
Reduction in right of use assets for modification and termination.
Reduction in right-of-use assets for modification and termination
Amounts Included In Accrued Expenses And Accounts Payable Related To Property And Equipment
Amounts included in accrued expenses and accounts payable related to property and equipment
Amounts included in accrued expenses and accounts payable related to property and equipment
Document Annual Report
Equity [Line Items]
Equity [Line Items]
Equity [Line Items]
Operating lease liability statement of financial position [extensible list]
Operating Lease, Liability, Statement of Financial Position [Extensible Enumeration]
Lease Income, Total
Lease Income
Lease income
Unvested Restricted Common Stock [Member]
Non Vested Restricted Stock [Member]
Non Vested Restricted Stock
Postemployment Benefits [Abstract]
Maximum [Member]
Maximum [Member]
Maximum
Range [Axis]
Statistical Measurement [Axis]
Exercised
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
Receivables
Receivables, Net, Current
Receivables, Net, Current, Total
Common Stock, Value, Issued
Common Stock, Value, Issued, Total
Common Stock, Value, Issued, Beginning Balance
Common Stock, Value, Issued, Ending Balance
Common stock aggregate fair value
Common stock $0.001 par value; 50,000,000 shares authorized, 2,349,480 and 1,601,252 shares issued and outstanding at December 31, 2025 and at December 31, 2024, respectively
Dividends [Axis]
Dividends [Axis]
Royalty [Member]
Net operating loss carryforwards
Deferred Tax Assets, Operating Loss Carryforwards
Deferred Tax Assets, Operating Loss Carryforwards, Total
Cybersecurity Risk Management Processes for Assessing, Identifying, and Managing Threats [Text Block]
Tax Credit Carryforward [Axis]
Tax Credit Carryforward [Axis]
State income tax, net of federal tax benefit
Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Percent
Operating lease area.
Operating Lease Area
Operating Lease Area
Entity Public Float
Preferred stock, shares authorized
Preferred Stock, Shares Authorized
Two Thousand Twelve Stock Option Plan [Member]
Two Thousand Twelve Stock Option Plan Member
Proceeds From The Issuance Of Common Stock And Pre Funded Warrants, Net Of Offering Costs
Proceeds from the issuance of common stock and pre funded warrants, net of offering costs.
Proceeds from the issuance of common stock and pre funded warrants, net of offering costs
Schedule of Debt [Table Text Block]
Schedule of Debt
Agreement Type [Domain]
Agreement Type Domain
Related Party Transaction [Line Items]
Related Party Transaction [Line Items]
Entity Registrant Name
Debt Disclosure [Text Block]
Debt
Lease termination date.
Lease Termination Date
Lease termination date
Entity Voluntary Filers
Other Nonoperating Income (Expense)
Other Nonoperating Income (Expense), Total
Other income , net
Subsequent Events [Abstract]
Banking and Thrift, Interest [Abstract]
Cybersecurity Risk Management Positions or Committees Responsible [Flag]
Consolidated Entities [Domain]
Effective tax rate, Amount
Effective tax rate, Amount
Income Tax Expense (Benefit)
Measurement Frequency [Axis]
Summary Of Significant Accounting Policies [Line Items]
Summary Of Significant Accounting Policies [Line Items]
Summary Of Significant Accounting Policies [Line Items]
Post Marketing Approval [Member]
Post Marketing Approval Member
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Entity Common Stock, Shares Outstanding
Concentrations of Credit Risk
Concentration Risk, Credit Risk, Policy [Policy Text Block]
he University of Texas MD Anderson Cancer Center [Member]
The University of Texas MD Anderson Cancer Center [Member]
The University of Texas MD Anderson Cancer Center.
Consolidation Items [Axis]
Net Proceeds From Issuance of Common Stock and Pre Funded Warrents
Net proceeds from issuance of common stock and pre funded warrents.
Net proceeds
Payments to Acquire Property, Plant, and Equipment, Total
Purchases of property and equipment
Payments to Acquire Property, Plant, and Equipment
Share-based payment award granted
Granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period
Total assets
Assets
Sale Of Series A two Preferred Stock Value
Sale of series a two preferred stock value.
Sale of Series A-2 preferred stock
Property, Plant and Equipment [Table]
Property, Plant and Equipment [Table]
Options exercisable, at end of period
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term
Income Statement [Abstract]
Derivative Liability, Fair Value of Collateral
Fair value of the derivative liability
Houston, TX [Member]
Houston Texas [Member]
Houston Texas [Member]
Exercise Of Prefunded Warrants Shares
Exercise of prefunded warrants shares.
Exercise of prefunded warrants
Accounting for Stock-Based Compensation
Share-Based Payment Arrangement [Policy Text Block]
Debt Instrument Redemption Period One
Debt Instrument, Redemption, Period One [Member]
License agreement commencing date
License Agreement Commencing Date
License agreement commencing date.
Additional Number Of Warrants Issued
Additional number of warrants issued.
Additional number warrants issued
Stock Issued During Period, Shares, New Issues
Additional common stock issuance
Issuance of common stock in registered direct offering, net of offering costs (in shares)
Vested
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period
Restricted shares vested
Net loss per share, diluted
Net loss per share, diluted
Net income (loss) per share, diluted
Earnings per share, Diluted
Schedule of Segment Reporting Information, by Segment [Table Text Block]
Summary of Segment Reporting Information
Operating Segments [Member]
Operating Segments [Member]
Relationship to Entity [Domain]
Title and Position [Domain]
City Area Code
Auditor Name
Laboratory equipment [Member]
Laboratory Equipment [Member]
Laboratory Equipment [Member]
Additonal tranche facility
Line of Credit Facility, Maximum Borrowing Capacity
Accrued Payments
Commitments and Contingencies Disclosure [Line Items]
Commitments and Contingencies Disclosure [Line Items]
Accrued Payments
Sublease term amendment
Sublease Term Commenced End Date Amendment
Sublease term commenced end date amendment.
Sale of Stock, Description of Transaction
Sale of Stock Description
Operating Lease, Weighted Average Remaining Lease Term
Weighted-average remaining lease term (years)
Segment Reporting Information [Line Items]
Total lease cost
Lease, Cost
Lease, Cost, Total
Net Proceeds from Underwriting
Assets and Liabilities Eliminated upon Consolidation [Abstract]
Assets and Liabilities Eliminated upon Consolidation [Abstract]
License Agreement Terms [Member]
Preferred Stock Dividends and Other Adjustments
Preferred Stock Dividends and Other Adjustments, Total
Cumulative preferred dividends
Cash and Cash Equivalents
Cash and Cash Equivalents, Policy [Policy Text Block]
Property and equipment, net
Property and equipment, net
Property, Plant and Equipment, Net
Property, Plant and Equipment, Net, Beginning Balance
Property, Plant and Equipment, Net, Ending Balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Number
Number of stock options granted and fully vested
Loss from operations
Operating Income (Loss)
Loss from operations
Retained Earnings [Member]
Accumulated Deficit
Due Date Axis
Due date [Axis]
Stock-based compensation expense
Stock based compensation expenses
Share-Based Payment Arrangement, Noncash Expense
Share-based Payment Arrangement, Noncash Expense, Total
Measurement Input, Price Volatility [Member]
Expected Volatility
Employees [Member]
Employees [Member]
Employees [Member]
Weighted-average discount rate
Operating Lease, Weighted Average Discount Rate, Percent
Fair Value, Inputs, Level 1 [Member]
Quoted Prices in Active Markets for Identical Assets/Liabilities (Level 1) [Member]
Class of Stock [Line Items]
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation
Net cash flows from financing activities
Components of Lease Expense
Lease, Cost [Table Text Block]
Deferred Tax Liability Right of Use Asset
Deferred Tax Liability Right of Use Asset.
Deferred Tax Liability Right of Use Asset, Total
Right-of-use asset
Auditor Location
Derivative Contract [Domain]
Loss Contingency, Name of Plaintiff
Loss contingency, name of plaintiff
Potentially Dilutive Shares Excluded from Computation of Diluted Net Loss Per Share
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Income Tax Authority [Domain]
Income Tax Jurisdiction [Domain]
Number of additional option available to the underwriter to purchase
Number of additional option available to the underwriter to purchase.
Number Of Additional Option Available To The Underwriter To Purchase
Entity Interactive Data Current
Income Statement Location [Domain]
Statement of Income Location, Balance [Domain]
Warrants Expiration Date
Warrants Expiration Date
Warrants expiration date
Cash flows from operating activities:
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation [Abstract]
Stock Issued During Period, Shares, Issued for Services
Shares issued as consideration for board service fees ( in shares)
Percentage of Original Principal Due as a Final Payment
Percentage of original principal due as a final payment.
Percentage of original principal due as a final payment
Line of Credit Facility, Current Borrowing Capacity
Loan and Security Agreement
Initial borrowing
Entity Tax Identification Number
Price per Share
Share Price
Par value per share
Issuance Of Prefunded Warrants In Registered Direct Offering Value
Issuance of prefunded warrants in registered direct offering avlue.
Issuance of prefunded warrants in registered direct offering
Local Phone Number
Share-Based Payment Arrangement, Option, Exercise Price Range, Shares Outstanding
Share-Based Payment Arrangement, Option, Exercise Price Range, Shares Outstanding, Ending Balance
Share-Based Payment Arrangement, Option, Exercise Price Range, Shares Outstanding, Beginning Balance
Stock option to purchase shares
Leases other than short-term lease
Short-Term Lease, Cost
Reclassification Of Warrant Liability To Equity Value
Reclassification of warrant liability to equity value.
Reclassification of Warrant Liability to equity
Auditor Opinion [Text Block]
Restructuring Costs
Restructuring Costs, Total
Restructuring costs
Warrant [Text Block]
The entire disclosure pertaining to the warrant.
Warrants
Accounting Policies [Abstract]
Series A One and Series A Two Convertible Preferred Stock [Member]
Series A One and Series A Two Convertible Preferred Stock [Member]
Series A one and series A two convertible preferred stock.
Previously Reported [Member]
Previously Reported [Member]
Revenue
Collaboration revenue
Revenue from Contract with Customer, Excluding Assessed Tax
Revenue from Contract with Customer, Excluding Assessed Tax, Total
Revenues
License Expense
Amount of expense related to License payments.
License expense
Lessee, Operating Lease, Liability, to be Paid, Year Four
2027
Class of Stock [Domain]
Class of Stock [Domain]
Options available for future grant
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant
Expected recognition period
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Professional services
Accrued Professional Fees, Current
Start-up and pre-clinical studies
Deferred Tax Assets Start Up And Pre Clinical Studies
Deferred tax assets start up and pre clinical studies.
Issuance of Common Stock to Underwriters
Stock, Class of Stock [Table]
Entity Emerging Growth Company
Tax Credit Carryforward, Name [Domain]
Tax Credit Carryforward, Name [Domain]